Brand/Generic Flashcards
Epzicom
Abacavir/Lamivudine
NRTI for HIV
(EAL)
abacavir: HLA-B*5701, potential MI risk
Acetaminophen/Codeine
Tylenol #3
Zovirax
Acyclovir
Tx for Herpes (HSV, Varicella, Zoster)
- dosed on IBW
- herpes labialis - 5x daily x 4 days
- herpes zoster - 5x daily for 7 days (start within 72 hours)
Differin
Adapalene
Retinoid for acne
Abuterol
ProAir
Proventil
Ventolin
Albuterol/Ipratropium
Combivent
Fosamax
Alendronate
Bisphoshonate for osteoporosis
- ONJ, femur fracture, esophagitis, hypocalcemia, renal impairment
- separate from antacids at least 2 hours
Zyloprim
Allopurinol
xanthane oxidase inhibitor for gout
- MUST use with colchicine or NSAID for initial 3-6 months due to high rate of gout attacks
- HLA-B*5801 - SJS/TEN, don’t use if +
- hepatotoxicity
Xanax
Alprazolam
benzodiazepine, CIV
pregnancy - crosses placenta
Entereg
Alvimopan
Gut motility stimulator - for hospitalized surgery patients to decrease risk of post-op ileus
Opioid antagonist
- Max doses: 15
- CI: therapeutic doses of opioids for > 7 days
Pacerone (PO)
Nexterone (IV)
Amiodarone
Class 3 anti-arrhythmic = K channel
- boxed warnings: pulmonary toxicity, hepatotoxicity, must be hospitalized for IV LD
- CI: iodine HS
- thyroid (iodine + conversion inhibition), photosensitivity (slate blue skin), optic and peripheral neuropathy, hypotension, bradycardia, corneal microdeposits
- GAL PLAT
- LATTIN
- t1/2 ~60 days
Elavil
Amitriptyline
Tricyclic Antidepressant - tertiary amines
- CI: w/ MAO, methylene blue, linezolid
- QT prolongation/fatal arrhythmias, anticholinergic (> with tertiary)
Norvasc
Amlodipine
DHP CCB
- peripheral edema/HA/flushing/palpitations/reflex tachycardia, gingival hyperplasia (more with non-DHPs)
Lotrel
Amlodipine/Benazepril
DHP-CCB/ ACEi
Amoxicillin/Clavulanate
Augmentin
Adderall
Amphetamine/Dextroamphetamine
CNS stimulant
- misuse can cause sudden death/serious CV events
Arimidex
Anastrozole
Aromatase Inhibitor for postmenopausal breast cancer
- ONLY POSTmenopausal women unless using GnRH agonist as well
- higher risk of CVD compared to SERMs
- higher risk of osteoporosis
- hot flashes/night sweats, arthralgia/myalgia
Eliquis
Apixaban
DOAC
Emend
Aprepitant (PO), fosaprepitant (IV)
Substance P NK-1 Antagonist
for CINV
- decrease dexamethasone dose - 3A4 inhibitors
Abilify
Aripiprazole
SGA - blocks D2 and 5HT2A receptors
- the 2 A’s: activating and akathisia
Reyataz
Atazanavir
Protease Inhibitor (stage 7)
- “A” for acidic environment required!
- Take with food (all PIs)
Tenormin
Atenolol
Beta Blocker
- Selective for B1 (AMEBBA)
- do NOT d/c abruptly
Tenoretic
Atenolol/Chlorthalidone
Strattera
Atomoxetine
Selective NE reuptake inhibitor for ADHD
- boxed warning: suicidal ideation
- CI: MAO within 14 days
- SE: decr appetite, insomnia, somnolence, dry mouth, HTN, tachycardia
- DO NOT OPEN CAPSULE - ocular irritant
Lipitor
Atorvastatin
HMG-CoA inhibitor
Astepro
Azelastine (nasal)
Antihistamine H-1 receptor for allergy
Azithromycin
Zithromax
Macrolides 50s ribosubunit (CLiMS)
Cortisporin
Bacitracin/Neomycin/Polymyxin B/ Hydrocortisone
Lioresal
Baclofen (intrathecal)
skeletal muscle relaxant
QVAR RediHaler
Beclomethasone
inhaled corticosteroids
Lotensin
Benazepril
ACE inhibitors
Tessalon Perles
Benzonatate
antitussive anesthesia of vagal sensory nerve fibers that mediate cough
Cogentin
Benztropine
Anticholinergic for Parkinson’s and symptoms of antipsychotics (EPS) – Primarily for TREMORS
- anticholinergic SEs
Diprolene Cream
Betamethasone diprionate
High potency corticosteroid 0.6
Lotrisone
Betamethasone / Clotrimazole
Bictarvy
Bictegravir / Emtricitabine / TAF
INSTI / NRTI
(BETA)
- don’t use CrCl < 30
- separate cations - take INSTI 2 hours before or 6 hours after
- all INTIs: weight gain, HA, insomnia
Lumigan
Bimatoprost
decreases IOP for open angle gluacoma
- another version for eyelash growth (Latisse)
- 1 drop QHS
Bromfed DM
Brompheniramine / Psuedoephedrine / Dextromethorphan
Antihistamine / anticongestant / Antitussive
Pulmicort
Budesonide
ICS
- only neb option of ICS - jet neb only
- DOC for asthma maintenance in pregnancy
Symbicort
Budesonide/ Formoterol
(symBUFort)
- can be used prn as a rescue inhaler in asthma (reduces exacerbations compared to albuterol alone)
Bumex
Bumetanide
Loop diuretic
Furosemide 40 mg = Bume 1 mg = Torsemide 20 mg
ototoxicity
Belbuca (buccal)
Butrans (patch)
Buprenorphine
Opioid partial agonist
Zyban
Bupropion (Wellbutrin)
Serotonin and NE reuptake inhibitor ?? used for depression and smoking cessation
Miacalcin
Calcitonin
for severe hypercalcemia (last line)
- nasal spray or injection (one nostril daily)
- hypocalcemia, MALIGNANCY risk, HSR to salmon derived products
Invokana
Canagliflozin
Invokamet
Canagliflozin/Metformin
Xeloda
Capecitabine
Prodrug of fluorouracil
Antimetabolite Pyrimidine analog chemotherapy
- DPD deficiency incr risk of toxicity
- hand-foot syndrome, diarrhea, mucositis
- leucovorin incr efficacy of 5-FU
Tegretol
Carbamazepine
AED, bipolar, trigeminal neuralgia
- HLA-B*1502
- therapeutic range: 4-12 mcg/mL
- boxed warnings: SJS/TEN, aplastic anemia, agranulocytosis
- CI: myelosuppression
- hyponatremia/SIADH
- fetal harm
- autoinducer
Sinemet
Carbidopa/Levodopa
- CI: non-selective MAOi within 14 days
- SE: dizziness, orthostasis, hallucinations, psychosis, dyskinesias, brown/black discoloration of urine, hemolysis risk (+ coombs test)
- do not d/c abruptly
Soma
Carisoprodol
CIV, antispasmodic
- poor 2C19 metabolizers wil have incr carisoprodol concentrations
Coreg
Carvedilol
- non-selective BB + alpha-1 blockers
- 1/3 options for HF
- TAKE WITH FOOD
- conversions to and from ER/IR are NOT 1:1
Celebrex
Celecoxib
COX-2 selective NSAID
- CI: sulfonamide allergy
- highest COX-2 selectivity (greatest risk of MI/stroke)
Keflex
Cephalexin
TussiCaps
Chlorpheniramine / Hydrocodone
Sensipar
Cinacalcet
ESRD hypercalemia or in hyperparathyroidism
- decreases PTH, Ca and PO4
Cipro
Ciprofloxacin
Celexa
Citalopram
SSRI
- max dose: 40 mg/day (QTc prolongation)
max 20 mg/day age > 60
- bleeding, hyponatremia
Cleocin (PO, injection)
Clindamycin
50S (CLiMS), mostly gram + coverage, some anaerobes
- no renal dose dose adjustment!
- boxed warning for C. diff colitis
- induction D-test performed on S. aureus - flattened zone indicates resistance (covers some CA-MRSA)
Clobex
Clobetasol
topical glucocorticoid, very high potency
Klonopin
Clonazepam
Catapres
Clonidine
Plavix
Clopidogrel 75 mg QD
- prodrug - 2C19
- DDI: omeprazole and esomeprazole decrease efficacy (2C19 inhibitors)
- TTP
- stop 5 days prior to elective surgery
Clozaril
Clozapine
Antipsychotic “last line”
- REMS severe neutropenia (to start ANC ≥ 1500, stop if ANC < 1000)
- neutropenia/agranulocytosis, myocarditis and cardiomyopathy, seizures
Tybost
Cobicistat
CYP3A4 inhibitor to enhance PI for HIV
- with food
- lots of DDIs - 3A4 and pgp inhibitor
Colcrys
Colchicine
treat or prevent gout flares
- CI: with pgp or strong 3A4 inhibitor
- warnings: myelosuppression
- max dose: 1.8 mg/day, start within 36 hours of symptom onset for flare
- SE: N, D, muscle damage
Welchol
Colesevelam
treats high cholesterol, approved for glycemic control in diabetes
- SE: increased TG, constipation, cramping
- take WITH meal
- colesevelam is option in pregnant patients
Amrix
Cyclobenzaprine (Flexeril)
Gengraf
Cyclosporine
Neoral, GenGraf (modified) – great F
Sandimmune (non-modified)
Restasis (optic)
- not interchangeable, greater F with modified
- SE: incr BP, nephropathy, hyperkalemia, hypomagnesia, hirsuitism, gingival hyperplasia, edema, incr BG, neurotoxicity, QT prolongation
- trough levels, many DDIs
Pradaxa
Dabigatran
Direct thrombin inhibitor (factor IIa)
- missed dose: take unless within 6 hours of next dose
- antidote: idarcizumab (praxbind)
- swallow capsule whole; do NOT administer via NG
- CI: mechanical heart valves
- SE: dyspepsia
Farxiga
Dapagliflozin
Prezista
Darunavir
Protease inhibitor (stage 7)
- caution with sulfa allergy
- take WITH food (PIs)
Pristiq
Desvenlafaxine
SNRI
DexPak
Decadron
Dexamethasone
Dexilant
Dexlansoprazole
PPI
- take withOUT regards to meals
- capsules can be opened - no chewing
Valium
Diazepam
Voltaren
Diclofenac
NSAID COX nonselective
Bentyl
Dicyclomine
treats GI spasms from IBS (antispasmodic)
- used for diarrhea
- anticholinergic
Lanoxin
Digoxin (Digox)
therapeutic ranges:
1. afib: 0.8 - 2 mcg/mL
2. HF: 0.5 - 0.9 mcg/mL
- oral to IV –> decr dose 25-50%
- digoxin level drawn 12-24h after dose
- with inhibitors –> decr dose 50%
- hypo - kalemia, magnesemia, hypercalcemia increase the risk of digoxin toxicity
Cardizem
Diltiazem (Tiazac)
non-DHP CCB
- May worsen HF!!
- constipation, edema, bradycardia, increased LFTs
Benadryl
Diphenhydramine
Lomotil
Diphenoxylate/ Atropine
CV
Aggrenox
Dipyridamole / ASA
dipyridamole MOA: inhibits the uptake of adenosine into plts –> inhibit plt aggregation
- hypotension
- not interchangeable with the two products separated
Tivicay
Dolutegravir
Triumeq
Dolugravir / Abcavir / Lamivudine
(TALD)
- HLA-B*5701
Dovato
Dolutegravir / Lamivudine
- don’t use if viral load > 500,000 copies in tx naive pt, +HBV, or no genotyping testing
Aricept
Donepezil
acetylcholinesterase inhibitor
- QHS dosing to decr nausea
- cardiac effects –> bradycardia
Pulmozyme
Dornase alfa
treats cystic fibrosis
Order of CF drugs:
1. bronchodilator - albuterol (open airway)
2. hypertonic saline (mobilize mucus)
3. dornase alpha (decrease viscosity to promote airway clearance)
4. chest physiotherapy (mobilize mucus to improve airway clearance)
5. Inhaled antibiotics
Cardura
Doxazosin
non-selective alpha blocker, BPH
- itraoperative floppy iris syndrome (IFIS)
- bedtime dosing
- XL version = OROS (ghost tablet)
Vibramycin
Doxycycline
Marinol
Dronabinol
Cymbalta
Duloxetine
SNRI
Atripla
Efavirenz / Emtracitabine / TDF
(a triple E and Td)
- empty stomach qhs (neuropsych symp with efavirenz)
Genvoya
Elvitegravir / Cobistat / Emtricibine / TAF
(GEETAC)
Stribild
Elvitegravir / Cobistat / Emtricibtabine / TDF
(SCEnTED)
Jardiance
Empagliflozin
Descovy
Emtricitabine / TAF
(Dis the ETA or DETA)
Truvada
Emtricitabine / TDF
(TETd)
Vasotec
Enalapril
Baraclude
Entecavir
NRTI treatment for Hep B
- E –> empty stomach
Calciferol
Ergocalciferol
vitamin D2
Lexapro
Escitalopram
SSRI, S enantiomer of citalopram
- Max dose: 20 mg/day (QTc prolongation)
- hyponatremia/SIADH
- increased bleeding risk
Nexium
Esomeprazole
PPI, PO and injection (IV - panto, esomep)
- avoid with clopidogrel
- capsule can be opened - dont chew
Premarin
Estrogen
used in post-menopausal women for vasomotor symptoms
- unopposed estrogen (with uterus) can increase risk of endometrial cancer
- increased risk of breast cancer, VTE, stroke
Lunesta
Eszopiclone
for insomnia
CIV
Yasmin / Yaze
Ethinyl estradiol / drospirenone
drospirenone: increased K, increased risk of clotting, decreases bloating
Nuvaring
Ethinyl estridiol / etonogesterol
- inserted x 3 weeks, removed for week 4
- if left in > 4 weeks, confirm not pregnant, put new ring in and use backup x 7days
Seasonique
Ethinyl estradiol / levonorgestrel
- extended, only 4 periods per year/ q3mo
Junel
Leostrein
Microgestin
Ethinyl estradiol / norethindrone
Ortho Tri-Cyclen
Tri-Sprintec
Ethinyl estradiol / norgestimate
Zarontin
Ethosuximide
for absence seizures
- SJS/TEN, blood dyscrasias
Zetia
Ezetimibe
inhibits absorption of cholesterol in small intestine
- myalgias
- main effect on decr LDL
Pepcid
Famotidine
antihistime H2 receptor for GERD
Tricor
Trilipix
Antara
Fenofibrate
PPARa activators –> increases catabolism of VLDL –> decr TGs
- CI: severe liver disease, including primary biliary cirrhosis
- do NOT give gemfibrozil with ezetimibe or statins
- can incr LDL when TGs are high, increased LFTs
- myalgias (increase risk when coadministered with statins)
Duragesic
Fentanyl
- can start when ≥ 60 mg morphine equivalence per day for ≥ 7 days
- CYP3A4 substrate (MORFH = methadone, oxycodone, remifentanil, fentanyl, hydrocodone)
Dificid
Fidaxomicin
cdiff infection
Proscar
Propecia
Finasteride
5-alpha reductase for urinary retention, alopecia
- CI: women of childbearing age
- sexual side effects, breast enlargement
- 6 months of tx may be required for max benefit
- should shrink prostate/ decr PSA levels
Diflucan
Fluconazole
Prozac
Fluoxetine
SSRI
- long t1/2, wait 5 weeks before starting MAOi, no taper required
- activating, take in AM
- Sarafem - for PMDD (Sara has PMDD so thats why she needs Sarafem)
Flovent
Arnuity Ellipta
Fluticasone
Advair Diskus
Fluticasone / salmeterol
Breo Ellipta
Fluticasone / vilanterol
(FVeo)
Lasix
Furosemide
IV:PO 1:2
Neurontin
Gabapentin
Lopid
Gemfibrozil
do not use with statins or ezetimibe (myopathy risk)