Diuretics Flashcards

0
Q

Major site of NaCl and NaCO3 reabsorption

Reabsorption of amino acids, glucose and numerous cations

Uric acid site of transport

A

PCT -BIBO!

Acted upon by CAI

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1
Q

Site of action of diuretics

A

Carbonic anhydrase inhibitor: PCT
Loop diuretics: Thick Ascending Limb
Thiazides: DCT
Potassium-sparing diuretics: CCT (cortical CT)
Osmotic diuretics: PCT, Descending limb of loop of Henle, CD

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2
Q

CAI used for glaucoma and mountain sickness

A

Acetazolamide

SimD: Dorzolamide, Brinzolamide, Dichlorphenamide, Methazolamide

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3
Q

IMPORTANT SE of Acetazolamide

A

ACIDazolamide causes ACIDosis

Hyperchloremic metabolic acidosis, potassium wasting, renal calcium stones, HepEnceph on cirrhotic pxs

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