Diuretics Flashcards
0
Q
Major site of NaCl and NaCO3 reabsorption
Reabsorption of amino acids, glucose and numerous cations
Uric acid site of transport
A
PCT -BIBO!
Acted upon by CAI
1
Q
Site of action of diuretics
A
Carbonic anhydrase inhibitor: PCT
Loop diuretics: Thick Ascending Limb
Thiazides: DCT
Potassium-sparing diuretics: CCT (cortical CT)
Osmotic diuretics: PCT, Descending limb of loop of Henle, CD
2
Q
CAI used for glaucoma and mountain sickness
A
Acetazolamide
SimD: Dorzolamide, Brinzolamide, Dichlorphenamide, Methazolamide
3
Q
IMPORTANT SE of Acetazolamide
A
ACIDazolamide causes ACIDosis
Hyperchloremic metabolic acidosis, potassium wasting, renal calcium stones, HepEnceph on cirrhotic pxs