Cholinoreceptor Blockers Flashcards
FIRST CHOICE Treatment for Organophosphate Poisoning DUMBBELSS Diarrhea Urination Miosis Bronchospasm Bradycardia Excitation Lacrimation Sweating Salivation
Atropine
Nonselective antimuscarinic cholinoreceptor blocker for both cycloplegia (ciliary muscle paralysis) and mydriasis (pupillary dilatation)
Atropine
Cholinesterase regenerator used as Antidote for organophosphate poisoning and nerve gas poisoning
MUST BE ADMINISTERED BEFORE 6-8 HOURS
Pralidoxime
Muscarinic cholinergic antagonist used as treatment for tremors for Parkinson’s disease
Benztropine
SimD: Biperiden, Trihexyphenydil
TRy to PARK your BENZ here, BIP!
Muscarinic cholinergic antagonist used as TOC for Asthma and COPD
Ipatropium
SimD: Tiotropium
For patients with COPD and heart disease bec it is less toxic
Symptoms of Atropine toxicity
Hot as a hare - atropine fever Dry as a bone - decreased secretions Red as a beet - atropine flush Blind as a bat - blurred vision Mad as a hatter - CNS toxicity Tachycardia, arrhythmia
Nicotinic cholinergic antagonist used as obsolete Tx for hypertension
Causes ORTHOSTATIC HYPOTENSION
Hexamethonium
SimD: Trimethaphan
Only DEPOlarizing neuromuscular blocker
Succinylcholine
Kapag nakapagDEPOsit ka sa toilet, SUCCess yun!
Nondepolarizing neuromuscular blockers
Tubocurarine
Pancuronium
Atracurium
Vecuronium