DISEASES OF INFANCY AND CHILDHOOD I

Question 1

________________ represent primary errors of morphogenesis in which there is an intrinsically abnormal developmental process

Answer 1

malformations

Question 2

______________ result from secondary destruction of an organ or body region that was previously normal in development

Answer 2

disruptions

Question 3

____________ like disruptions represent an extrinsic disturbance of development rather an intrinsic error of morphogenesis

Answer 3

deformations

Question 4

__________ is a cascade of anomalies triggered by one initiating aberration

Answer 4

sequence

Question 5

_________ is a plant tetratogen contained in the corn lily; pregnant sheep who feed on this plant give birth to lambs with severe craniofacial abnormalities including holoprosencephaly and cyclopia

Answer 5

cyclopamine

Question 6

__________ is an an antiepileptic and a recognized tetratogen during pregancy
disrupts expression of __________ proteins

Answer 6

homeobox proteins

Question 7

thee most common cause is ____________ also known as hyaline membrane disease because of the deposition of a layer of hyaline proteinaceous material in the peripheral airspaces of infants who succumb to this condition

Answer 7

neonatal respiratory distress syndrome