Dietary supplements/Natural meds Flashcards
Dietary supplements are regulated by…
the Dietary Supplement Health and Education Act (DSHEA) of 1994
What is DSHEA?
Act that states manufacturers of dietary supplements must proved that the products are safe….but NOT effective
Under DSHEA, who must prove that dietary supplements are not safe?
The FDA is responsible for “proving” a supplement is not safe for it to be removed from the market
Supplement manufacturers can make what claims?
claims about nutrient content
relationship to health
normal body function/structure comment
What company/establishment establishes standards for for dietary supplements?
United states pharmacopeia (USP)
St Johns wort induces CYP3A4 and what other enzymes?
P-gp
2C19»_space; 2C9 >1A2
Other side effects of st johns wort:
photosensitivity
decr seizure threshold
serotonin syndrome w/ other serotonergic drugs
Natural products that can incr bleeding risk
5 G’s: garlic, ginger, ginkgo, ginseng, glucosamine
fish oils
vit E
willow bark (salicyclate)
Natural products that can cause hepatotoxicity
black cohosh (for menopause) kava (stress/anxiety)
Natural products that can cause cardiac toxicity:
Ephedra (taken off the market)
Bitter orange
Any stimulants used to promote weight loss
Name for Vitamin A
Retinol
Name for Vit B1
thiamine
What can thiamine deficiency lead to?
Wernicke’s encephalopathy (mental confusion, ataxia, tremor)
can lead to permanent brain damage if not treated
Name of Vit B2
riboflavin
Name of Vit B3
Niacin