ADHD Flashcards

1
Q

Primary symptoms of ADHD

A

inattention
hyperactivity
impulsivity

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2
Q

first line treatment for ADHD

A

psychotherapy

pharmacotherapy: stimulants

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3
Q

Inattention symptoms

A

6 or more symptoms for children up to 16 y/o
5 or more for pts 17 and older:

fails to pay attention
does not follow through on instructions
fails to finish schoolwork
difficulty organizing tasks
looses things 
easily distracted
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4
Q

Hyperactivity & impulsivity symptoms

A

6 or more symptoms for children up to 16 y/o
5 or more for pts 17 and older:

fidgets/squirms
can't be seated for long periods of time
talks excessively
has trouble waiting for turns
interrupts others
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5
Q

natural product used in ADHD

A

fish oil

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6
Q

ER formulations are preferred in children (t/f)

A

True

children would require 2nd dose at school for better symptom control

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7
Q

Which stimulants are usually 1st line and why?

A

Methylphenidate

better side effect profile

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8
Q

What drugs can be used to help with sleep if pts have trouble sleeping on stimulants

A

Clonidine IR
benadryl
Intuniv
Kapvay

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9
Q

Stimulant MOA

A

block the reuptake of NE and dopamine

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10
Q

Stimulant titration

A

up titrated every 7 days

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11
Q

Stimulants need to be tapered off when stopping (t/f)

A

False

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12
Q

Stimulant boxed warning

A

Risk for misuse and abuse

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13
Q

Stimulant contraindications

A
w/in 14 days of a MAO inhibitor
history of CV disease
serious anxiety disorder
glaucoma
hyperthyroidism
tourette's (other tic disorders)
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14
Q

Stimulant warnings

A

Severe CV events
Pre-existing psychiartic disorders (incr suicide risk)
Incr risk of seizures
Loss of appetite (decr growth in children)
Risk of serotonin syndrome w/ serotonergic drugs

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15
Q

stimulant side effects

A
nausea
insomnia
HA
irratability
blurry vision dry mouth
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16
Q

Ritalin dosage forms

A

Tab
chewable tab
Solution (Methylin)

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17
Q

ER methylphenidate that releases some drug IR and some as ER

A

Ritalin LA
Aptensio XR
both caps

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18
Q

Methylphenidate ER brands

A

Concerta (OROS tablet)
Metadate ER
Methylin ER

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19
Q

Methylphenidate ER caps can be sprinkled onto applesauce and given right away (t/f)

A

true

20
Q

Qullichew ER

A

methylphenidate XR chew tab

can be cut in half

21
Q

Quillivant XR

A

methylphenidate XR suspension
25 mg/ml
shake for at least 10 secs before giving

22
Q

Cotempla XR-ODT

A

methylphenidate XR ODT

23
Q

Daytrana

A

methylphenidate transdermal patch

24
Q

Daytrana onset of action

A

2 hours

25
Q

Daytrana duration of action

A

9 hours

Apply to alternating hips daily

26
Q

General max dose of all methylphenidate formulations

A

60 mg/day

ConcertaL 72 mg/day

27
Q

Focalin

A

dexmethylphenidate

when converting from Ritalin: give 1/2 of methylphenidate dose

28
Q

Evekeo

A

Amphetamine tab

29
Q

Adzenys ODT

A

amphetamine ODT

30
Q

Dyanavel XR

A

amphetamine suspension

31
Q

What foods can decrease levels of amphetamines?

A

acidic foods/juice, vitamin C

32
Q

Vyvanse

A

lisdexamfetamine

caps and chewable tab

33
Q

Capsule cannot be opened (t/f)

A

False

can be opened and mixed with water, yogurt or orange juice

34
Q

Desoxyn

A

Methamphetamine

35
Q

Strattera

A

atomoxetine

36
Q

Strattera MOA

A

selective NE reuptake inhibitor

37
Q

Strattera boxed warnigns

A

suicidal ideation

38
Q

Strattera main side effects

A
HA
insomnia
somnolence
hypertension, tachycardia
dry mouth 
nausea, abd pain
39
Q

Strattera caps can be opened and mixed with liquids (t/f)

A

False

do not open caps, very irritating to stomach

40
Q

Strattera metabolism

A

CYP 2D6 substrate

41
Q

Intuniv

A

Guanfacine ER

42
Q

Intuniv dosing

A

4 mg max when used with stimulants

7 mg max when used alone

43
Q

Intuniv metabolism

A

CYP3A4

44
Q

Kapvay

A

clonidine ER

45
Q

Kapvay dosing

A

0.1 mg qHS

Max: 0.4 mg/day

46
Q

alpha-2 agonist side effects

A

somnolence
dizziness
HA
fatigue

Must be tapered: decr dose every 3-7 days to decr chance of rebound HTN, nervousness, anxiety

47
Q

Strattera can cause renal/hepatic damage

A

Hepatic