diabetes Flashcards
insulin pumps are usually given too
TYPE 1
what is a job of insulin pump
is to mimic the body in production of the baseline insulin
if you are type 2 diabetic what type of insulin will you generally need
intermediate/long acting since you still have some function
side effects of insulin
can drop levs too low causing hypo
due to anabolic hormone causes lip hypotrophy so always change sites of injection
alcohol and diabtes relationship
drinking increases risk of type 2 diabtest
generally alcohol raises blood sugar as it has a lot of calories and can lead to weight gain
however if you are taking insulin and alcohol your risk of hypoglycemia is increased as it prevents the liver from releasing the excess glucose stored.
hypoglcyemia
tx
usually below 4 mmol
glucogel
glucose or dextrose tablets
if unconscious glucagon injection
ideal hb1ac for a diabetic is
why do we care about the levels
6.5%
because over the hreshold you are at risk of complications relared to diabets
what is hb1ac
test for diagnosing type 2, or lookingat how well controlled your type 2 is looks at your rbc for the last 3 months and how controlled your blood sugars are
once the glucose binds to the rbc it stays there so you know.
hb1ac vs normal blood test
normal : looks at your sugar now
hb1 ac _ in the past 3 moths
c peptide
is in direct proportiion to the amount of insulin so helps differentiate between type 1 and type 2 not really a diagnostic tool
what other confition is closely linked to type 1
thyroid disease
random glucose over ?
11
high glycemic index
cause a rapid spike in insulin levels so short
sick day rules and why
when you are ill your blood sugar increases as a way to cope with the stress, in normal people the body just produces more insulin to counter the effects.
so diabetes who are ill will often high higher levels than usual
its important not to stop taking insulin
to keep eating/hydrating
pt should regularly check their glucose levles
normal gfr
> 90
side effects of metfrmine
gi upset- will stop if they perists
lactic cidosis risk increased with renal problems
microvascular complications -daibtes
nephro
retinopathy
neuropathy
macrovascular diabetes
brain
pvd
heart
different types of insulin
rapid acting - usually 15 mins before
short acting - usually 30 mins before
intermediate
long acting
what is mixed insulin
you take mixed insulin, that means you take it before meals and don’t need to take background (or basal) insulin at a different time.
signs of diabetes
polyuria
dipsia
polyphagia
loss of weight
numbness/pareesthia
autonomic dysfunction - urinary (nerves that empty bladder reduced so can leas to retention and hence UTI increased and sometimes incontinence)
erectile dysfunction , bowels
orthostatic hypo
gastroporiss
sweat glands - both
group of drugs
biguinides - metformin
sulfonoreus - glicazide
SGLT- dapaglipozin
DPP4 inhibitors - stigaliptin
1st 2nd line
- metformin
- glicazide
3.
Which is more important in the management of type 2 diabetes; blood pressure control or blood glucose control
bP control
why does diabetes increase risk of stroke
sugar damages the walls of the vessels
this increases the risk of atherosclerosis
having diabtes also increases risk of clot formation affects the clotting factors
also havng diabtes also increases the risk of hypertension which is a rf for stroke
what is the major cause of death in people with type 2 diabetic
cardiovascular disease
What is the normal glycated haemoglobin level for non-diabetic
less than 6%
Something we really want to focus on in a patient that has diabetes
But pressure control is even more important than sugar control
Destinations you would perform to diagnose somebody with diabetes
Random blood glucose ≥ 11.1mmol/l
Fasting plasma glucose ≥ 7mmol/l
2-hour glucose tolerance ≥ 11.1mmol/l
HbA1C ≥ 48mmol/mol (6.5%)
for diabetics with hypertension whats first line
ace as they are renoprotective
target range for blood pressure
<140/90 - same for normal people under 80
target bp for people over 80
<150/90
how to reat gastropereis
need to stimulate motility so metoclorpromide and domperidone
sometimes it can actually be cause by bacteria so abx are given