Dermatology 3 Flashcards

1
Q

Basal cell carcinoma is also known as?

A

rodent ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the most common skin malignancy?

A

basal cell carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Basal cell carcinoma

Malignant tumour of _________ ________
Normally affects ______ ______ ____ individuals

A

Malignant tumour of epidermal keratinocytes
Normally affects middle aged-older individuals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

RF for BCC

A

Risk factors include pale skin type, UV sun exposure,
immunosuppression, previous skin cancer, inherited syndromes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Common sites of BCC

A

Common sites include face, arms, legs (sun exposed areas)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Name the different types of BCC

A

Nodular

Superficial

Sclerosing

Pigmented

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which BCC is most common type on the face?

A

Nodular BCC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which BCC tends to occur in younger patients?

A

Superficial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which BCC is skincoloured waxy, scar-like ?

A

Sclerosing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which BCC is brown, blue or greyish lesion that may resemble melanoma?

A

Pigmented

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the managemenf of BCC

A

• Surgical excision is usual treatment of choice - allows histological examination of
the tumour and margins
• Radiotherapy when surgery is inappropriate
• Topical treatment (imiquimod cream) or photodynamic therapy for superficial
subtype
• Prognosis is excellent especially for smaller lesions - locally invasive if untreated
but metastatic spread is extremely rare
• High risk of developing further lesions (~50% ppl develop further lesion within 5
years) and affected individuals at ^ risk of developing other forms of skin cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which skin malignacy is most common in black people?

A

Squamous Cell Carinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

TRUE OR FALSE

BCC

Usually grow over weeks – months, can be painful, often ulcerated

A

FASLE

SCC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

RF for SCC

A

Risk factors include UV sun exposure, (HPV infection in Black
people), immunosuppression and smoking (particularly SCC of lips)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Common sites SCC

A

Most SCCs are found on sun-exposed sites, particularly the face,
lips, ears, hands, forearms, lower legs & anogenital region in Black
people

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Management of SCC

A
  • Surgical excision - treatment of choice
  • Radiotherapy - for large, non-resectable tumours
  • Early stage tumours >90% 5 year survival
  • Approximately 10% rate of metastasis overall
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

________ ____– excessive
keratin production results in a
hard horn; this can overlie SCC,
pre-cancerous lesions or warts

A

Cutaneous horn – excessive
keratin production results in a
hard horn; this can overlie SCC,
pre-cancerous lesions or warts

18
Q

______________ – a rapidly
growing keratinising skin nodule
which can look identical to SCC
but resolves without treatment.

A

Keratoacanthoma – a rapidly
growing keratinising skin nodule
which can look identical to SCC
but resolves without treatment.

19
Q

Actinic Keratoses is also known as

A

solar keartosis

20
Q

Where does Actinic Keratoses develop usually?

A

Develop in areas of sun damage (face,
backs of hands, bald scalps), usually
older individuals. Rarely seen in Black
people

21
Q

Actinic Keratoses is a maligannt tumour

TRUE OR FALSE

A

FALSE

Premalignant - small minority (<1%)
may eventually progress to SCC

22
Q

Actinic Keratoses treatment options?

A

• Treatment options include cryotherapy and curettage for individual lesions or topical 5-fluorouracil for field treatment

23
Q

WHat is bowne’s disease

A

SCC in situ

24
Q

Where is bowen’s disease found?

A

Commonly found on the lower leg or trunk, more
often in women.

25
Bowen's Disease can be mistaken for?
Bowen’s disease may resemble discoid eczema, psoriasis or superficial basal cell carcinoma.
26
Bowen's disease treatment?
Treated by cryotherapy, curettage, topical 5- fluorouracil or imiquimod, or photodynamic therapy.
27
What is the ABCDE rule for Malignant melanoma
28
What is the weighted 7 point checklist? Malignant melanoma
29
What is a Malignant melanoma
An invasive malignant tumour of the epidermal melanocytes, which has the potential to metastasise
30
RF for Malignant melanoma
* Increasing age * UV exposure * Previous invasive melanoma or melanoma in situ * Previous non-melanoma skin cancer * Many melanocytic naevi (moles) especially if atypical naevi * Strong family history of melanoma with 2 or more first-degree relatives affected * Fair skin that burns easily
31
Different types of malignant melanoma?
Superficial Spreading Mucosal and Ocular Melanomas Lentigo Maligna Melanoma Nodular Melanoma
32
Which melanoma is common on the face in elderly population; Related to long-term cumulative UV exposure
Lentigo Maligna Melanoma
33
Which melanoma is * Common on the lower limbs * Young and middle-aged adults * Related to intermittent high intensity UV exposure
Superficial Spreading
34
Which melanoma arise on lips, eyelids, vulva, penis, anus and on sclera
Mucosal and Ocular Melanomas
35
36
Which melanoma is * Common on the trunk * Young and middle aged adults * Related to intermittent high- intensity UV exposure
Nodular Melanoma
37
Management for Malignant melanoma?
Surgical excision - definitive treatment •Sentinel lymph node biopsy for higher risk lesions •Surgery if nodal disease •Radiotherapy – only for metastatic disease •Targeted or immunotherapy if systemic metastases
38
Recurrence of melanoma based on _______ thickness (thickness of tumour): Explain this?
Recurrence of melanoma based on **Breslow** thickness (thickness of tumour): * \<0.76mm thick – low risk, * 0.76mm-1.5mm thick – medium risk, * \>1.5mm thick – high risk
39
Prognosis of rmelanoma?
* 5 year survival rates based on the TNM classification: * Stage 1 (T \<2mm thick, N0, M0) – 90%, * Stage 2 (T\>2mm thick, N0, M0) – 80% * Stage 3 (N≥1, M0) – 40-50% * Stage 4 (M ≥ 1) – 20-30%
40