Dental development Flashcards
What are the 3 embryonic layers that the body tissues develop from?
Ectoderm e.g. spinal chord
Mesoderm e.g. muscles
Endoderm- e.g. respiratory system
What is the ectomesenchyme?
The tissue which makes up the Neural crest, a cell type between the ectoderm and the neural tube.
What does the ectoderm develop?
Tooth enamel.
What does the ectomesenchyme develop?
The tooth and supporting structures
Developing face and jaw.
What condition is this?
What has caused it?
Mandibulofacial dysostosis.
Caused by failure of the ectomesenchymal cells to migrate.
This causes reduction in mandibular size and less teeth.
What happens in the initiation stage of tooth development.
Development of the Primary epithelial Band.
This splits into the
Vestibular lamina (forms the buccal sulcus)
Dental lamina (forms the enamel organ )
What happens in the morphogenesis stage of tooth development?
The dental lamina develops into the:
Enamel organ
Neural crest develops Dental papilla.
Enamel organ forms a cap over the dental papilla.
Describe the parts of the enamel organ .
Internal enamel epithelium
External enamel epithelium
Cervical loop (where they meet)
What is the placode?
Another word for the enamel organ.
What condition is this?
Hypohidrotic ectodermal dysplasia.
Abnormal development of the structures that develop from the ectoderm.
Causing conical shaped and missing teeth.
What happens in cytodifferentiation?
Enamel organ develops into 4 layers:
IEE
EEE
Stratum intermedium
Stellate reticulum
There is an extension on the lingual side of the dental lamina for the tooth’s permanent succesor.
What happens in the matrix secretion stage?
Dentine and enamel are secreted.
How is dentine formed?
Dental papila cells differentiate into Odontoblasts.
These lay down pre-dentine (mostly collagen).
This is then mineralised to produce hydroxyapatite.
What condition is this?
and why does it happen?
Dentinogenesis imperfecta.
It is a hereditary condition involving the production of dentine.
How is enamel produced?
- Differentiation- ameloblasts. These enlongate and the nucleus migrates to the basal end.
- secretion- Ameloblasts secrete amelogens. to lay down the partially mineralised matrix
- The matrix proteins are removed to increase mineral content.
- protective- The ameloblasts regress to form the reduced enamel epithelium.
What is this disease, and what causes it?
Amelogenesis imperfecta.
Caused by abnormal maturation of enamel.
