Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CRR > Coronary Circulation > Flashcards

Coronary Circulation Flashcards

1
Q

What does left side contain?

A

Oxygenated blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does diffusion coefficient allow?

A

Oxygen to diffuse across max of 1mm tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How does the heart have its own circulation?

A

Coronary arteries , squeeze shut during heart contraction and fill during relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What 2 coronary arteries branch from aorta?

A

Left coronary artery passes anterior to LA and divides into Anterior inerventricular (LAD) and Circumflex branches

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What does LAD do?

A

Extend along anterior inerventricular sulcus and supplies blood to both ventricules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What does circumflex do?

A

runs along coronary sulcus and provides LV and RA with blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What does Right coronary artery do?

A

Inferior to RA with small atrial branches supply RA with blood
branches to posterior intraventricular and right marginal branches

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does posterior interventricular branch do?

A

Follow post.Interve.Sulc and supplies both ventricle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does right marginal branches do?

A

Follows coronary sulcus and RV with blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does coronary veins do?

A

Deoxygenated blood drains from coronary capillaries to veins transfers blood to thin wall coronary sinus drains RA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What does coronary sinus do?

A

Supply deoxygenated blood via great cardiac (anterior) and Middle cardiac vein (posterior)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

When does ischaemia occur?

A

Partial obstruction of coronary artery cause myocardial ischemia causes hypoxia decreased ATP - modifies actin/myosin, inhibits na/k pump and inihibits ATP K channe;s - induce angina pectoralis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does Angina Pectoralis occur?

A

Severe pair in neck chin or left arm
tight sensation in chest
additional exertions at rest
lead to myocardial infarction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is myocardial infarction?

A

Myocardial cells induce by blockage of blood supply to region of heart, forms scar tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What happens to Heart muscle in MI?

A

loose contractile strength
Scar tissue isolate AV node
Ventricular fibrillation - asynchronous contracts of ventricles
Defibrillation depolarises cell to resynchronize

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is CAD? coronary artery disease

A 
Medical problem
accumulation of atherosclerotic plaques in coronary arteries
low blood flow
leads to- no  sigh
chest pain
heart attack
17
Q

What are lipoproteins?

A

Lipids transported in blood with proteins, inner tryglycerides and hydrophobic shells of phospholipisds cholesterol and apoproteins

18
Q

What is Lipoprotein classification?

A

HDL-C particles
LDL-C particles
VLDL low desne lipprotein
Chylomicrons

19
Q

How are lipoproteins transported?

A

different pathways by apoprotein in phospholipid shell

20
Q

What is apoprotein function?

A

ligands for receptors enabling direct transport B100 in LDLC particles for steroid synthesis

21
Q

What happens to cholesterol and triglycerides?

A

absorbed by ileum and transported via chylomicrons in lymph to blood

22
Q

What happens in muscle and adipose tissue?

A

Triglycerides are hydrolysed and tissues taken up by fatty acids and glycerol

23
Q

What are chylomicrons?

A

Still contain cholesterol esters pass to liver bind to receptors, endocytosed

24
Q

Wheres cholesterol stored?

A

In liver, oxidised to bile acids secreted in bile and endogenous pathway

25
Q

What is process for formation of atherosclerotic plaque?

A 
Initial early
inflammatory
cell filtrate
intermediate
advance
26
Q

What are statins?

A

inhibit HMG-CoA and mevalonate pathway for hypercholesterolemia

27
Q

What are Fibrates?

A

Increase hepatic LDLC uptake in hypercholesterolemia

28
Q

What are Bile acid binding resins?

A

Reduce cholesterol absorption from intestines LDL recepttors for clearnace from blood cause diarrohea

CRR (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions