Circulation 3 Flashcards
What is circulatory shock
Circulatory failure causes poor perfusion of vital organs
In practice, shock = Low blood pressure and its physiological consequences
What are the main causes of shock
- Hypovolaemic
- Septic
- Cardiogenic
- Other
What does normal BP require
Enough blood in system (5 litres in adult)
Smooth muscle in vessels having certain ‘tone’
Heart pumping blood
(tone=amount of tension in muscle)
Explain the physiological mechanisms which try to maintain blood pressure in shock
-2 carotid bodies and 2 sinuses on either side of neck
-Consist of groups of cells which sense partial pressure of oxygen
-Cartoid bodies ‘sense’ BP change, send signal to brainstem, signals heart to pump harder/faster
-Physiological response to low blood pressure = faster pulse (heart rate)
-Adrenaline causes heart to pump harder/faster
What is another way in which BP is maintained
Increased vascular tone in vessels in limbs and abdomen, blood pushed up to chest and head
Keeps vital organs alive
Describe Hypovolaemic shock
Low bp - severe reduction in amount of blood in circulation
High pulse - physiological response to low bp
Describe cardiogenic shock
heart unable to pump sufficent blood to brain and vital organs
Describe septic shock
Bacterial infection affects BP
Cardiac muscle looses it’s tone – slow HR = bradycardia
What is vascular tone
contractile activity of vascular smooth muscle cells in walls of small arteries and arterioles
Describe the complications of shock
Brain injury (ischaemic infarction of brain tissue)
Decreased perfusion of kidneys, initially reversible, then more severe (ischaemic necrosis of renal tubules)