Chapter 6 - The Integumentary System Flashcards
Contains the epidermis or superficial epithelium and dermis
Cutaneous membrane or skin
Located primary in dermis and come out through epidermis , contains hair , nails , and exocrine glands
Accessory structures
Abrasion , fluid loss , immune system , chemicals
Protect
Salts, water, organic wastes
Excrete
Cells that make keratin, a protien that makes cells harder and tougher
Keratinocytes
Maintenance of body temperature
Synthesis of vitamin d3
Storage of lipids
Sensation of touch , pressure , pain and temperature
Functions of skin
epidermal ridges begin here as interdigitations with dermal papillae
Stratum germinativum or stratum basale
Stem cells for keratinocytes are here as well as merkel cells and melanocytes
Dividing cells push other cells up through the layers to the outer stratum cornermen
Stratum germinativum or stratum Basele
Means “spiny layer”
Also contains langerhans cells (immune system)
Stratum spinosum
Means “grainy layer”
Cells produce keratin and keratohylalin ; these proteins dry and toughen the cells leading to flattening
Cells die as the move upward through this layer
Stratum granulosum
Thin layer of clear keratin packed cells found only in thick skin
Stratum lucidum
The outermost layer of dead keratinized cells and water resistant
Stratum cornermen
Deeper four-fifth of the dermis
Reticular layer
Composed of areolar tissue , one - fifth of dermis
Papillary layer
Fibrous connective tissue , blood vessels , sweat glands and hair follicles are there
Dermis
Due to epidermal pigmentation and dermal circulation
The color of skin
Most important pigment for determining skin color
Melanin
Black, brown, yellow brown protein produced in ___
Melanocytes
Genetically controlled
Skin color
A pigment of minor importance
Carotene
Found in orange colored foods and squash
Carotene
Cause orange- yellow color in light skinned person
Carotene
A blue appearance to skin or mucus membrane due to lack of oxygen ; particularly seen on lips and nails
Cyanosis
A yellow color to the skin and whites of the eyes due to inability of liver to secrete bike ; bilirubin , a yellow pigment from breakdown of RBCs , builds up the body
Jaundice
A hormone that can stimulate increased melanin production in melanocytes
Melanocytes stimulating hormone
May cause skin darling , like Addison’s disease
Msh producing tumors
A condition where individuals lose their melanocytes, depigmentation is iregular both in extent and size of light spots and how light the spots are. Genetic and is an autoimmune disease
Vitiligo
Major risk factor for skin cancer
uV exposure from the sun
A scaly area
Keratosis
Most common but least dangerous ; takes many years to metastasize
Basal cell carinoma
Fairly common in older individuals; takes many months to a few years to metastasize
Squamous cell carcinoma
Least common , but extremely dangerous , takes weeks to months to metastasize
Malignant melanoma
Irregular shape to a mole
Asymmetry
Indistinct or irregular border to a mole
Border
Mixture of colors , or very dark colors , may also ooze or bleed
Color
A mole that is large than about 5mm in diameter , a little bigger than a pencil eraser
Diameter
Major cause of wrinkles
UV exposure
The active form of vitamin D3
Calcitriol
Redness from blood
Erythema
Necessary for proper nervous system development and maintenance
Folate
Areolar tissue containing capillaries , lymphatics and sensory neurons ; named for the dermal papillae , little bumps or hills that project upward between the epidermal ridges
Papillary layer
Dense irregular connective tissue with collagen and elastic fibers , contains all the cells expected in proper connective tissue , deep to papillary layer ,
Reticular layer
2 of the biggest factors contributing to early wrinkle formation
UV exposure and smoking
A cut parallel to the direction between the fibers gap less and heal with much less scarring than a cut across fibers . Used by surgeons to help minimize healing time and scaring
Line of cleavage
The network of arteries at the border of the reticular layer and the subcutaneous layer
Cutaneous plexus
The network of arteries in the papillary layer
Papillary plexus