Chapter 5: the structure and fucntion of large biological molecules Flashcards
All living things are made up of four classes of large biological molecules:
carbohydrates, lipids, proteins, and nucleic acids
Within cells, small organic molecules are joined together to form
larger molecules
___ are large molecules composed of thousands of covalently connected atoms
Macromolecules
Molecular structure and function are ___
inseparable
A ___ is a long molecule consisting of many similar building blocks
polymer
A polymer is a long molecule consisting of many similar building blocks These small building-block molecules are called ___
monomers
Three of the four classes of life’s organic molecules are polymers:
Carbohydrates Proteins Nucleic acids
A ___ occurs when two monomers bond together through the loss of a water molecule
dehydration reaction (dehydration synthesis)

Polymers are disassembled to monomers by ___, the addition of a water molecule, a reaction that is essentially the reverse of the dehydration reaction
hydrolysis

Each cell has thousands of different kinds of macromolecules
An immense variety of polymers can be built from a small set of monomers
___ include sugars and the polymers of sugars
Carbohydrates
The simplest carbohydrates are ___, or single sugars
monosaccharides
___ consist of two monosaccharides joined by a dehydration synthesis reaction
Disaccharides
Carbohydrate macromolecules are ___, polymers composed of many monosaccharides (sugar building blocks)
polysaccharides
Monosaccharides have molecular formulas that are usually multiples of CH2O
Glucose (C6H12O6) is the most common monosaccharide. Other examples are fructose and galactose.
Monosaccharides are classified by
The number of carbons in the carbon skeleton
trioses, pentoses, hexoses

Though often drawn as linear skeletons, in aqueous solutions many sugars form rings
Monosaccharides serve as a major fuel for cells and as raw material for building molecules

Two monosaccharides can join to form a disaccharide via dehydration synthesis reaction
This covalent bond is called a ___
glycosidic linkage
Examples of disaccharides include ___
maltose, sucrose and lactose

___ the polymers of sugars (may have a few hundred to a few thousand monosaccharides joined).
These have different functions in the cell:
Storage roles
Structural roles
Polysaccharides,
___, a storage polysaccharide of plants, consists entirely of glucose monomers
Starch
___ is a storage polysaccharide in animals
Humans and other vertebrates store glycogen mainly in liver and muscle cells
Glycogen
The polysaccharide ___ is a major component of the tough wall of plant cells
Like starch, cellulose is a polymer of glucose, but the glycosidic linkages differ
cellulose
Enzymes that digest starch can’t ___ cellulose
hydrolyze
Cellulose in human food passes through the digestive tract as ___
insoluble fiber
Some microbes use enzymes to digest cellulose (these are called ___)
cellulase enzymes
___, another structural polysaccharide, is found in the exoskeleton of arthropods(ie beetles, lobsters)
Chitin
Chitin also provides structural support for the cell walls of many fungi
Chitin is similar to cellulose except it has a nitrogen containing functional group on each glucose monomer.
Lipids are the one class of large biological molecules that ___
do not form polymers
The unifying feature of lipids is having little or no ___
affinity for water
Lipids are ___ becausethey consist mostly of hydrocarbons, which form nonpolar covalent bonds
hydrophobic
Fats are constructed from two types of smaller molecules: ___
glycerol and fatty acids
___ is a three-carbon alcohol with a hydroxyl group attached to each carbon
Glycerol

A ___consists of a carboxyl group attached to a long carbon skeleton
fatty acid

Fatty acids vary in length (number of carbons) and in the number and locations of double bonds
___ fatty acids have the maximum number of hydrogen atoms possible and no double bonds
Saturated

___ fatty acids have one or more double bonds
Unsaturated

Fats made from saturated fatty acids are called ___, and are solid at room temperature
Most animal fats are saturated
saturated fats
Fats made from unsaturated fatty acids are called ___ or oils, and are liquid at room temperature
Plant fats and fish fats are usually unsaturated
unsaturated fats
A diet rich in saturated fats may contribute to cardiovascular disease through plaque deposits
___is the process of converting unsaturated fats to saturated fats by adding hydrogen
Hydrogenation
Hydrogenating vegetable oils also creates unsaturated fats with trans double bonds
These trans fats may contribute more than saturated fats to cardiovascular disease
Humans and other mammals store their fat in ___
adipose cells
The major function of fats is ___
energy storage
Adipose tissue also cushions vital organs and insulates the body