!! Chapter 40 Principles of Fluid, Electrolytes, and Acid-Base Balance Flashcards
Water in the body functions primarily to:
- Transport nutrients to cells and wastes from cells
- Transport hormones, enzymes, blood platelets, and red and white blood cells
- Facilitate cellular metabolism and proper cellular chemical functioning
- Act as a solvent for electrolytes and nonelectrolytes
- Help maintain normal body temperature
- Facilitate digestion and promote elimination
- Act as a tissue lubricant
What is the total body water/fluid in a healthy person?
Approximately 50% to 60% of body weight in a healthy person.
Body fluid is located in what 2 fluid compartments?
- intracellular fluid
- extracellular fluid
The fluid constituting about 70% of the total body water or 40% of the adult’s body weight.
Intracellular fluid
The fluid accounting for about 30% of the total body water or 20% of the adult’s body weight.
Extracellular fluid
The extracellular fluid includes two major areas:
- the intravascular and interstitial compartments
- and third minor compartment is the transcellular fluid
The liquid component of the blood that surrounds tissue cells and includes lymph (i.e., fluid found within the vascular system)
Intravascular fluid/plasma
What 2 things separate the intracellular and extracellular compartments?
The capillary walls and cell membranes
What 3 factors cause variations in fluid content?
- person’s age
- body fat
- biological sex
__ cells contain little water, whereas __ tissue is rich in water.
Fat
Lean
Similarly, the decreasing percentage of body fluid in older people is related to an increase in ___.
Fat cells
How does the human body obtain fluids?
- 1st: Ingestion of liquids (provides the largest amount of water)
- 2nd: Food
- a by product of metabolism
___ has considerably more body fluid and ECF than an ___; more prone to fluid volume deficits
An infant
Adults
Liquids that hold a substance in solution (water)
Solvents
Substances dissolved in a solution (electrolytes and nonelectrolytes)
Solutes
Fluctuations in fluid intake and output can:
destabilize the balance between fluids and electrolytes.
The equilibrium between the acidity and alkalinity of body fluids is
acid–base balance.
Water passes from an area of lesser solute concentration to greater concentration until equilibrium is established
Osmosis
Tendency of solutes to move freely throughout a solvent (“downhill”)
Diffusion
Requires energy for movement of substances through the cell membrane from the lesser solute concentration to the higher solute concentration
Active transport
Passage of fluid through a permeable membrane from the area of higher to lower pressure
Capillary Filtration
What process is this:
- Solvent and solute particles move to equalize concentrations.
- No semipermeable membrane is involved.
Diffusion
What process is this:
- Only solvent particles move. Solute particles do not move.
- The movement is through a semipermeable membrane.
Osmosis
Osmolarity of a Solution:
same concentration of particles as plasma.
Isotonic
Osmolarity of a Solution:
greater concentration of particles than plasma
Hypertonic
Osmolarity of a Solution:
lesser concentration of particles than plasma
Hypotonic
A ___ solution has a greater osmolarity, causing water to move out of the cells and to be drawn into the intravascular compartment, causing the cell to shrink.
Hypertonic
What are the 4 Fluid Losses?
Kidneys: urine
Intestinal tract: feces
Skin: perspiration
Insensible water loss (fever)
What are the 9 primary organs of homeostasis?
- kidneys
- cardiovascular system
- lungs
- adrenal glands
- pituitary gland
- thyroid gland
- nervous system
- parathyroid glands
- GI tract
What increases the blood flow in the body and increases renal circulation?
The thyroid gland
What inhibits and stimulates mechanisms influencing fluid balance?
The nervous system
What regulates the level of calcium in ECF?
Parathyroid glands
What absorbs water and nutrients that enter the body through this route?
GI tract
What stores and releases ADH?
Pituitary gland
What helps the body conserve sodium, save chloride and water, and excrete potassium?
Adrenal glands
What regulates oxygen and carbon dioxide levels of the blood?
Lungs
What pumps and carries nutrients and water in body?
Cardiovascular system
What filters 170 L of plasma and excrete 1.5 L of urine?
Kidneys
Substance containing hydrogen ions that can be liberated or released.
Acid
Substance that can trap hydrogen ions.
Base
What are the 3 Major Homeostatic Regulators of Hydrogen Ions?
Buffer systems
Respiratory mechanisms
Renal mechanisms
What are 3 types of buffer systems?
- carbonic acid- NA bicarbonate
- phosphate
- protein