!! Chapter 40 Principles of Fluid, Electrolytes, and Acid-Base Balance Flashcards
Water in the body functions primarily to:
- Transport nutrients to cells and wastes from cells
- Transport hormones, enzymes, blood platelets, and red and white blood cells
- Facilitate cellular metabolism and proper cellular chemical functioning
- Act as a solvent for electrolytes and nonelectrolytes
- Help maintain normal body temperature
- Facilitate digestion and promote elimination
- Act as a tissue lubricant
What is the total body water/fluid in a healthy person?
Approximately 50% to 60% of body weight in a healthy person.
Body fluid is located in what 2 fluid compartments?
- intracellular fluid
- extracellular fluid
The fluid constituting about 70% of the total body water or 40% of the adult’s body weight.
Intracellular fluid
The fluid accounting for about 30% of the total body water or 20% of the adult’s body weight.
Extracellular fluid
The extracellular fluid includes two major areas:
- the intravascular and interstitial compartments
- and third minor compartment is the transcellular fluid
The liquid component of the blood that surrounds tissue cells and includes lymph (i.e., fluid found within the vascular system)
Intravascular fluid/plasma
What 2 things separate the intracellular and extracellular compartments?
The capillary walls and cell membranes
What 3 factors cause variations in fluid content?
- person’s age
- body fat
- biological sex
__ cells contain little water, whereas __ tissue is rich in water.
Fat
Lean
Similarly, the decreasing percentage of body fluid in older people is related to an increase in ___.
Fat cells
How does the human body obtain fluids?
- 1st: Ingestion of liquids (provides the largest amount of water)
- 2nd: Food
- a by product of metabolism
___ has considerably more body fluid and ECF than an ___; more prone to fluid volume deficits
An infant
Adults
Liquids that hold a substance in solution (water)
Solvents
Substances dissolved in a solution (electrolytes and nonelectrolytes)
Solutes
Fluctuations in fluid intake and output can:
destabilize the balance between fluids and electrolytes.
The equilibrium between the acidity and alkalinity of body fluids is
acid–base balance.
Water passes from an area of lesser solute concentration to greater concentration until equilibrium is established
Osmosis
Tendency of solutes to move freely throughout a solvent (“downhill”)
Diffusion
Requires energy for movement of substances through the cell membrane from the lesser solute concentration to the higher solute concentration
Active transport
Passage of fluid through a permeable membrane from the area of higher to lower pressure
Capillary Filtration
What process is this:
- Solvent and solute particles move to equalize concentrations.
- No semipermeable membrane is involved.
Diffusion
What process is this:
- Only solvent particles move. Solute particles do not move.
- The movement is through a semipermeable membrane.
Osmosis
Osmolarity of a Solution:
same concentration of particles as plasma.
Isotonic
Osmolarity of a Solution:
greater concentration of particles than plasma
Hypertonic
Osmolarity of a Solution:
lesser concentration of particles than plasma
Hypotonic
A ___ solution has a greater osmolarity, causing water to move out of the cells and to be drawn into the intravascular compartment, causing the cell to shrink.
Hypertonic
What are the 4 Fluid Losses?
Kidneys: urine
Intestinal tract: feces
Skin: perspiration
Insensible water loss (fever)
What are the 9 primary organs of homeostasis?
- kidneys
- cardiovascular system
- lungs
- adrenal glands
- pituitary gland
- thyroid gland
- nervous system
- parathyroid glands
- GI tract
What increases the blood flow in the body and increases renal circulation?
The thyroid gland
What inhibits and stimulates mechanisms influencing fluid balance?
The nervous system
What regulates the level of calcium in ECF?
Parathyroid glands
What absorbs water and nutrients that enter the body through this route?
GI tract
What stores and releases ADH?
Pituitary gland
What helps the body conserve sodium, save chloride and water, and excrete potassium?
Adrenal glands
What regulates oxygen and carbon dioxide levels of the blood?
Lungs
What pumps and carries nutrients and water in body?
Cardiovascular system
What filters 170 L of plasma and excrete 1.5 L of urine?
Kidneys
Substance containing hydrogen ions that can be liberated or released.
Acid
Substance that can trap hydrogen ions.
Base
What are the 3 Major Homeostatic Regulators of Hydrogen Ions?
Buffer systems
Respiratory mechanisms
Renal mechanisms
What are 3 types of buffer systems?
- carbonic acid- NA bicarbonate
- phosphate
- protein
Which of the chemical buffer systems is the most important buffer system of the body in that it buffers as much as 90% of the hydrogen of ECF?
Carbonic acid- sodium bicarbonate buffer system.
For normal cellular functioning to occur, the pH of body fluids must remain between:
7.35 - 7.45
What two compensatory mechanisms are designed to help maintain homeostasis?
- respiratory (changes RR to balance CO2 and Oxygen)
- renal (metabolic) (can keep Hydrogen or release them into urinary tract depending on what they need)
What are the Four acid–base imbalances that can occur?
Respiratory acidosis and alkalosis and metabolic acidosis and alkalosis
Occur when carbonic acid or bicarbonate levels become disproportionate.
Acid-Base imbalances
Deficiency in amount of water and electrolytes in ECF with near-normal water/electrolyte proportions.
(Fluid is outside the cells
Decrease in circulation volume)
Hypovolemia
Decreased volume of water and electrolyte change
Dehydration
Distributional shift of body fluids into potential body spaces
Third-space fluid shift
Excessive retention/loss of water and sodium at the same time in the ECF
Hypovolemia
Above-normal amounts of water in extracellular spaces
Overhydration
Excessive ECF accumulates in tissue spaces, causing swelling.
Edema
Movement of fluid from space surrounding cells to blood
Interstitial-to-plasma shift
Fluid imbalances involve:
either volume or distribution of water or electrolytes
occurs with excessive loss or inadequate intake of fluid. (FVD)
Fluid volume deficit
occurs when water and sodium are lost at the same rate.
Isotonic fluid deficit or hypovolemia
occurs when water is lost in excess of sodium.
Hypertonic fluid volume deficit or dehydration
A change of 1 kg (2.2 lb) is equivalent to __ of fluid.
1 L (1000 mL)
A significant and visible indication of fluid volume excess
edema
Characterized by a lasting indentation in the skin when pressure is applied.
pitting edema
Occurs when there is obvious swelling. The tissue is too firm and hard to be indented.
Brawny edema
How do you grade an edema?
1+ : slight indentation (2mm), returns back to normal quick
2+ : deeper indentation (4mm), indentation lasts longer
3+ : Obvious indentation (6mm), indentation lasts several seconds
4+ : deep indentation (8mm), indentation remains several minutes
When fluid volume deficit is present, the skin __
remains pinched, or tented, after release.
In severe fluid volume deficit:
Mucous membranes are dry and sticky, with furrows in the tongue. Cracked lips.
Skin turgor can provide an indicator of ___.
fluid volume imbalance.
What are the 4 Parameters of Assessment?
Nursing history and physical assessment
Fluid intake and output
Daily weights
Laboratory studies
What are 4 Lab Studies to Assess for Imbalances?
Complete blood count
Serum electrolytes, blood urea nitrogen, and creatinine levels
Urine pH and specific gravity
Arterial blood gases
What are 6 Risk Factors for Imbalances?
Pathophysiology underlying acute and chronic illnesses
Abnormal losses of body fluids
Burns
Trauma
Surgery
Therapies that disrupt fluid and electrolyte balance
What are 3 Nursing Diagnoses Related to Imbalances?
Excess fluid volume
Deficient fluid volume
Risk for deficient fluid volume
What 2 tests show kidney function?
BUN and Creatinine
What do diffusion and osmosis both do?
Equalizes the concentration of two solutions
What are the 4 types of Isotonic solutions?
- D5W
- 0.9% NaCl (NS)
- D5 0.225% NaCl (NS)
- Lactated Ringers
What are the pH ranges for acid-base balances?
- Death: 6.80 and below
- Acidosis: 6.80 - 7.35
- Normal: 7.35 - 7.45
- Alkalosis: 7.45 - 7.80
- Death: 7.80 and above
What is a third-space fluid shift?
When fluid shifts to a different part of the body. ex; ascites (fluid in their stomach)
What is an example of fluid volume deficit?
- could be blood loss due got trauma
- vomiting
- not enough intake
Specific gravity range?
(dilute) 1.010 - 1.025 (concentrated)
What are diuretics?
water pills that decrease salt amount and increase water amount in the body. Pulls fluid from the system, and is eliminated through renal.
What are the 2 types of ions?
- Cations: pos charge
- Anions: neg charge
What are the major electrolytes?
- NA
- Potassium
- Calcium
- Magnesium
- Chloride
- Bicarbonate
- Phosphate
What electrolyte controls and regulates volume of body fluids?
Sodium
What electrolyte is the chief regulator of cellular enzyme activity and water content?
Potassium
What electrolyte involves nerve impulse, blood clotting, muscle contraction, and B12 absorption?
Calcium
What electrolyte involves the metabolism of carbohydrates and proteins, and the vital actions involving enzymes?
Magnesium
What electrolyte maintains osmotic pressure in blood, produces hydrochloric acid?
Chloride
What is the body’s primary buffer system?
Bicarbonate
What electrolyte is involved in important chemical reactions in the body, cell division, and hereditary traits?
Phosphate
What are the electrolyte levels?
magnesium, phosphorus, potassium, calcium, chloride, sodium.
magnesium: 1.3-2.1 mEq/L
phosphorus: 2.5-4.5 mEq/L
potassium: 3.5-50 mEq/L
calcium: 8.5-10.5 mg/dL
chloride: 95-105 mEq/L
sodium: 135-145 mEq/L
SODIUM IMBALANCES
Hyponatremia/Hypernatremia
POTASSIUM IMBALANCES
Hypokalemia (levels lower than 3.5 mEq/L)
Hyperkalemia (levels higher than 5.0 mEq/L)
CALCIUM IMBALANCES
Hypocalcemia (levels below 8.5 mg/dL)
Hypercalcemia (10.5 mg/dL)
MAGNESIUM IMBALANCES
Hypomagnesemia (levels less than 1.3 mEq/L)
Hypermagnesemia (levels more than 2.1 mEq/L)
PHOSPHORUS IMBALANCES
Hypophosphatemia (levels below 1.7 mEq/L)
Hyperphosphatemia (levels above 2.6 mEq/L)
Humans are made up of:
60% water and 40% solid
How much water is intracellular vs extracellular?
66% or 2/3 intracellular and 33% or 1/3 extracellular
ECF (extracellular fluid) is made up of:
Interstitial fluid: 80%
Plasma: 20%
Inside the cell is __, the outside of the cell is ___.
- negative
- positive
What condition is someone experiencing when they have fever and chills during a transfusion?
Febrile reaction
A decrease in arterial blood pressure will result in the release of:
renin
Symptoms of hypocalcemia:
- blood clotting
- seizure activity
- report of numbness/tingling
- muscle cramps
What is the standard drop factor of microdrip tubing?
60 gtt/mL
The primary extracellular electrolytes are:
sodium, chloride, bicarbonate
How do you calculate flow rate?
ml per hours x drop factor (gtt/mL) divided by minutes.
What are substances that are capable of breaking into particles called ions?
Electrolytes
Major electrolytes in the __ include sodium, chloride, calcium, and bicarbonate.
ECF
Major electrolytes in the __ include potassium, phosphorus, and magnesium
ICF