Chapter 25 (Digestion) Study Guide Flashcards
Why does the digestive system work as a disassembly line? (2 reasons)
1) To break down nutrients into forms that can be used by the body
2) To absorb them so they can be distributed to the tissues
What are the five stage of digestion? Where does ingestion usually occur?
1) Ingestion: typically at the oral cavity (mouth)
2) Digestion: mechanical and chemical breakdown of food
3) Absorption
4) Compaction
5) Defecation
1) Define mechanical digestion. Where does mechanical digestion occur?
2) Define chemical digestion. Chemical digestion is carried out by enzymes produced by what organs?
1) Mechanical digestion occurs with the grinding of the teeth and churning of the stomach, which break down food into smaller particles.
2) Chemical digestion is the hydrolysis of macromolecules into their monomers, and is carried out by digestive enzymes produced by salivary glands, stomach, pancreas, and small intestine
Which nutrients are already present in usable form without digestion and can be directly absorbed?
Vitamins, amino acids, minerals, cholesterol, and water
1) What enzyme is used to digest starch? What two organs produce the enzyme?
2) What are the three disaccharides?
3) What 3 enzymes digest disaccharides into monosaccharides? Where are they produced?
4) What are the three monosaccharides?
1) Amylase; produced by the salivary glands and pancreas.
2) Disaccharides: Maltose, sucrose, and lactose
3) Maltase, sucrase, and lactase digest disaccharides into monosaccharides. Produced in the small intestine.
4) Monosaccharides: Glucose, galactose, and fructose.
1) What are proteins broken down into?
2) What enzyme breaks down proteins in the stomach? How is that enzyme activated?
3) What enzyme breaks down proteins in the small intestine that was produced by the pancreas? How and where is this enzyme activated?
4) Why must these enzymes be released in an inactive form?
1) Proteins are broken down into large polypeptides, then peptides, then amino acids.
2) Stomach: Pepsin digests proteins; pepsinogen is activated into pepsin by HCl and later by pepsin.
3) Small intestine: Trypsin (produced by the pancreas) digests proteins.Trypsinogen is converted into trypsin, which is activated in the duodenum of the small intestine by enteropeptidase.
4) If released in an active form, these enzymes would begin to digest your own body’s proteins.
1) Fats (triglycerides) are broken down into what monomers?
2) What enzyme is used?
3) Why is bile needed?
4) Is bile an example of mechanical digestion or chemical digestion?
1) A monoglyceride and 2 fatty acids (which can then be broken down into a glycerol and 3 fatty acids.)
2) Lipase is the enzyme used
3) Bile is needed for lipase to work well becauses it emulsifies (breaks down) fats.
4) Bile is an example of mechanical digestion.
1) What are nucleic acids broken down into?
2) What group of enzymes are used?
1) DNA or RNA is broken down into nucleotides, which are then broken down into pentose sugars, nitrogen bases, and phosphate ions.
2) Nucleases are used
Define:
1) Absorption
2) Compaction
3) Defecation
1) Absorption: uptake of nutrients into epithelial cells of GI tract and then into the blood or lymph
2) Compaction: absorbing water and consolidating the indigestible residue into feces
3) Defecation: elimination of feces; usually at anus
1) What organs make up the gastrointestinal (GI) tract?
2) What are the accessory organs?
1) GI tract: stomach and intestines
2) Accessory organs: teeth, tongue, salivary glands, liver, gallbladder, and pancreas
What are the digestive tract layers from deepest to most exterior? (4)
1) Mucosa
2) Submucosa
3) Muscularis externa
4) Serosa
A) Where is the mucosa layer of the digestive tract? What does it line?
B) What are its three layers? Describe them
A) The deepest digestive tract layer that lines the lumen; its 3 layers are:
B)
1) Epithelium: Simple columnar in most of digestive tract, stratified squamous mouth through esophagus, and in lower anal canal
2) Lamina propria: loose connective tissue layer
3) Muscularis mucosa: thin layer of smooth muscle that creates grooves and ridges that enhance surface area and contact with food
Define MALT and where it’s found
Mucosa-associated lymphatic tissue (MALT): Found in the mucosa and serves for defense against pathogens
What is found in the submucosa layer of the digestive tract? What primary tissue type does it come from?
1) Blood vessels, lymphatic vessels, a nerve plexus, and in some places mucus-secreting glands (dump mucus into lumen).
-MALT extends into submucosa in some GI areas.
2) It’s a thicker layer of loose connective tissue
Describe the two layers of the muscularis externa. What is the purposes of sphincters (valves)?
1) Inner circular layer: in some places this layer thickens to form valves (sphincters) that regulate the passage of material through the tract
2) Outer longitudinal layer
1) What tissues make up the serosa?
2) When does the serosa become the adventitia?
1) Areolar tissue (thin layer) topped by simple squamous mesothelium
2) The pharynx, esophagus, and rectum have adventitia
1) The esophagus, stomach, and intestines have a nervous network called the ________ nervous system.
2) What does the system regulate and how?
3) What are the two plexuses of this nervous system?
1) Enteric
2) Regulates motility, secretions and blood flow. It can be independent of CNS and is primarily parasympathetic stimulated (sympathetic inhibits). It’s a neuronal network in the walls of esophagus, stomach, intestines.
3) Submucosa (Meissner) plexus and Muscularis externa (myenteric) plexus
Name and describe the two plexuses of the enteric nervous system
1) Submucosa (Meissner) plexus controls glandular secretions in muscosa and movement of muscularis mucosae
2) Muscularis externa (myenteric) plexus controls peristalsis and other contractions
1) What do the mesenteries do and what does it provide?
2) The lesser omentum extends from what?
3) The greater omentum extends from?
1) Mesenteries are connective tissue sheets that hold abdominal viscera in place but allow movement
2) Lesser omentum: extends from lesser curvature of the stomach to the liver
3) Greater omentum: hangs from greater curvature of the stomach; drapes small intestine like an apron
1) What is the purpose of the mesentery
2) What is the purpose of the mesocolon?
3) What does it mean to be retroperitoneal?
1) Mesentery: anchors small intestine to posterior wall
2) Mesocolon: anchors the colon to the abdominal wall
3) Retroperitoneal: Behind and outside the peritoneal cavity (ex: duodenum, pancreas, and parts of the large intestine)
1) What are short myenteric reflexes triggered by, and what do they do?
2) What are long vagovagal reflexes triggered by, and what do they do?
3) What three hormones are controlling the motility and secretion?
1) Short (myenteric) reflexes: Stretch or chemical stimulation in GI tract; triggers peristaltic contractions of swallowing
2) Long (vagovagal) reflexes: sensory information from GI tract interpreted by CNS. Parasympathetic stimulation of digestive motility and secretion
3) Gastrin, CCK and secretin control motility and secretion
1) The mouth is known as what two terms?
2) What extrinsic muscle alters the tongue’s position?
1) The oral or buccal cavity
2) The genioglossus muscle
Name the 4 groups of functions of the mouth
1) Ingestion (food intake)
2) Taste and other sensory responses to food
3) Chewing (mastication) and chemical digestion
4) Swallowing, speech, and respiration
What type of tissue is the mouth lined with and why is it slightly different in different areas?
Stratified squamous epithelium lines mouth:
-Keratinized in areas subject to food abrasion: gums and hard palate
-Nonkeratinized in other areas: floor of mouth, soft palate, and insides of cheeks and lips
1) What is the lingual frenulum?
2) What is the purpose of the lingual glands?
1) Lingual frenulum: secures the tongue to the floor of the mouth
2) Lingual glands: serous and mucous glands amid the extrinsic muscles; secrete a portion of the saliva
List the 4 functions of the tongue
1) Speech
2) Taste
3) Chewing
4) Swallowing
1) What does the palate separate?
2) What does it make it possible to do?
3) Where is the uvula located?
1) Palate separates the oral and nasal cavities
2) To breathe while chewing food
3) At the end of the soft palate
1) Define dentition.
2) What are the incisors used for?
3) What are canines used for?
4) What are premolars and molars used for?
1) Dentition: The teeth
2) Incisors: act to cut, nip or bite off food
3) Canine: act to puncture and shred food
4) Premolars and molars: broad surface for crushing, shredding, and grinding
1) How many adult teeth are there?
2) What is a dental caries?
3) What is gingivitis?
4) What is periodontal disease?
1) 32 adult teeth
2) Dental caries: Also called cavities, bacteria metabolize sugars and release acids that dissolve the minerals of enamel and dentin.
3) Gingivitis: inflammation of the gums
4) Periodontal disease: destruction of the supporting bone around the teeth which may result in tooth loss
1) What is mastication? What is it the first step of?
2) What two muscles are involved in chewing?
1) Mastication: Chewing; breaks food into smaller pieces to be swallowed and exposes more surface to digestive enzymes. The first step of mechanical digestion.
2) The masseter and temporalis perform the the raising and lowering of the jaw in chewing.
What are the 6 functions of saliva?
1) Moistens mouth
2) Begins starch and fat digestion
3) Cleanses teeth
4) Inhibits bacterial growth
5) Dissolves molecules so they can stimulate the taste buds
6) Moistens food and binds it together into bolus to aid in swallowing
1) What is the composition of saliva?
2) What does salivary amylase do and when?
3) What does lingual lipase do and when?
1) Saliva is a hypotonic solution of 97.0% to 99.5% water and the solutes salivary amylase, lingual lipase, mucus, lysozyme, IgA, and electrolytes.
2) Salivary amylase: begins starch digestion in the mouth
3) Lingual lipase: enzyme that is activated by stomach acid and digests fat after food is swallowed
1) What does the mucus in saliva do?
2) What does lysozyme in saliva do?
3) What does the IgA in saliva do?
1) Mucus: binds and lubricates a mass of food, aids swallowing
2) Lysozyme: enzyme that kills bacteria
3) Immunoglobulin A (IgA): antibody that inhibits bacterial growth
pH range: 6.8 to 7.0
1) What are the two types of salivary glands?
2) What is the purpose of intrinsic salivary glands?
1) Intrinsic and extrinsic
2) Intrinsic salivary glands all secrete saliva at a fairly constant rate, keeps your mouth moist throughout the day.
Name the 4 intrinsic salivary glands and where they’re located
1) Lingual glands: in tongue
2) Labial glands: in lips
3) Palatine glands: in roof of mouth
4) Buccal glands: in cheeks
There are three pairs of extrinsic salivary glands, name them and where they’re located. include which is related to mumps.
1) Parotid: located beneath the skin anterior to earlobe. Mumps is an inflammation and swelling of this gland caused by a virus.
2) Submandibular gland: located halfway along the body of the mandible; its duct empties at the side of the lingual frenulum
3) Sublingual gland: located in the floor of the mouth; has multiple ducts that empty into the floor of the mouth
1) Define salivation.
2) About how much saliva is produced per day by the extrinsic salivary glands?
3) Salivary amylase begins to digest what?
4) What is a bolus?
1) Salivation: The secretion of saliva
2) Extrinsic salivary glands secrete about 1 to 1.5 L of saliva per day
3) Salivary amylase begins to digest starches into sugars.
4) Bolus: A mass swallowed as a result of saliva binding food particles into a soft, slippery, easily swallowed ball
1) What drives the production of saliva, is it sympathetic or parasympathetic?
2) If you are have less and thicker mucus, is it sympathetic or parasympathetic?
1) Parasympathetic fibers stimulate the glands to produce an abundance of thin, enzyme-rich saliva (from either ingested food or the thought or smell of food)
2) Less, and thicker, saliva with more mucus: Sympathetic
1) When food is not being swallowed, what sphincter is contracted? Why?
2) What tissue lines the esophagus?
3) What is the outmost layer called in the esophagus?
1) The upper esophageal sphincter remains contracted when food isn’t being swallowed to keep air out of the esophagus.
2) It’s made of nonkeratinized stratified squamous epithelium
3) Adventitia
1) What is the name of the sphincter that opens into the stomach?
2) Why is that sphincter necessary?
3) Define heartburn.
4) Define deglutition; what coordinates it?
1) The lower esophageal (cardiac) sphincter.
2) Food pauses at the cardiac sphincter because of constriction to prevent stomach contents from regurgitating into the esophagus, which protects esophageal mucosa from erosive stomach acid
3) Heartburn: burning sensation produced by acid reflux into the esophagus
4) Deglutition: Swallowing, coordinated by the medulla oblongata