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HLST124: Microbiology > Chapter 23: Microbial Diseases of the Cardiovascular System > Flashcards

Chapter 23: Microbial Diseases of the Cardiovascular System Flashcards

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Biology 101 flashcards
1
Q

Septicemia

A
  • persistant pathogens or their toxins enter the blood
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2
Q

Sepsis

A

SIRIS

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3
Q

Septic shock

A

final stage

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4
Q

what is an example of septicemia

A

lymphangitis

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5
Q

what is an example of spesis

A

pueperal sepsis

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6
Q

pueperal sepsis is caused by

A

s. pyogenes (GAS)

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7
Q

pueperal sepsis

A
  • caused by s. pyogenes (GAS)
  • abdominal cavity infection
  • treatment: penicillin
  • often not caught
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8
Q

what is the treatment for pueperal sepsis

A

penicillin
- often not caught

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9
Q

Rhematic fever

A
  • “sequal to”
  • GAS
  • symptoms: fever, arthritis (nodules form), inflammation of the mitral valve 9valve replacement), chest pain, murmurs, death
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10
Q

what bacteria is rhematic fever caused by

A

s pyogenes

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11
Q

how does s pyogenes attach

A

m proteins

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12
Q

gangreen produces what toxin

A

Alpha toxin

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13
Q

alpha toxin

A
  • produced by Gangreen
  • breaks plasma membrane of blood vessels
  • inhibits formation of lecithin
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14
Q

gangreen causes

A

gun shot wounds, diabetics, improper abortion, fracture, deep wounds

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15
Q

Gangreen

A
  • produces alpha toxin
  • causes necrosis
  • symptoms: pain, fluid blood, blackening of skin (necrosis), gas formation (“pop and crackle noise) –> CO2, Hydrogen
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16
Q

what bacteria causes gangreen

A

Clostridium perfringes

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17
Q

progression of gangreen

A

Ischemia, necrosis, gangreen, gas gangreen

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18
Q

Ischemia

A

loos of blood suppy to the tissue

19
Q

necrosis

A

dealth of the tissue

20
Q

what toxins does anthrax produce

A
  • protective antigen
  • lethal toxin
  • edema toxin
21
Q

protective toxin

A

entery

22
Q

lethal toxin

A

evades phagocytosis

23
Q

edema toxin

A

swelling of entery

24
Q

Anthrax treatment

A

vaccine (not common)
- 6 doses + yearly

25
Q

anthrax was discovered by

A

robert koch

26
Q

what bacteria casues anthrax

A

bacillus anthracis
- endospore
- bioweapon
- spread through soil

27
Q

what are the three manifestations of Anthrax

A
  • GI
  • Pulmonary
  • skin/ cutaneous
28
Q

Gi manifestation of anthrax

A
  • hemmoraging
  • 50% morality rate
  • caused by undercooked, contaminated meat
29
Q

Pulmonary manifestation of anthrax

A
  • septicemia
  • 1005 mortality rate
  • inhalation of endospores
30
Q

Skin / Cutaneous manifestation of anthrax

A
  • eschar
  • 20% mortality rate
  • treatment: pencillin, cipro
31
Q

how is anthrax treated

A

Ciprofloxacin

32
Q

Spotted fever is caused by which bacteria

A

Rikettsia rickettsi

33
Q

spotted fever caused a

A

macular rash
- accompanied by fever and headache

34
Q

What micorbail doseases of the cardiovascular system are caused by protozoa

A

Malaria

35
Q

what are the hosts of malaria

A

mosqutios, humans

36
Q

life cycle of malaria in mosquitos

A

Sporozoite –> blood –> liver –> Meroites –> rupture –> blood RBC’s (ring stage)–> burst –> more merozoids produced –> male and female gametes –> zygote –> Sporozoite

37
Q

life cycle of malaria in humans

A

Sporozoite –> blood –> liver –> Meroites –> rupture –> blood RBC’s (ring stage)–> burst –> more merozoids produced –> released –> blood:RBC’s

38
Q

HHSV -4 / EBV

A

abnormalities in B cells
- growth + latency

39
Q

HHSV-4 / EBV causes (4)

A
  • Birkitt’s lymphoma
  • nasopharynx cancer
  • mono
  • chronic fatigue syndrome
40
Q

Birkitt;s lymphoma

A
  • fast growing tumor of the jaw
41
Q

Mono

A

-“kissing disease” (transmitted via saliva
- long incubation period (4-8weeks)
- affects 1.5 million collage students per year
- symptoms: fever, sore throat, fatigue, swollen lymph nodes, enlarged spleen

42
Q

chronic fatigue syndrome symptoms

A
  • decrease muscle
  • decrease memory
  • increase titer of EBV
43
Q

HHSV-5 / Cytomegalovirus (CMV)

A
  • inflammation of T cells
  • have inclusions (owl eyes)
  • transmitted: saliva, semen, vaginal fluid, placenta
  • causes retinitis (blindness)

HLST124: Microbiology (18 decks)

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