Chapter 2: Integrative Approaches to Psychopathlogy Flashcards
____ dimensions of the multidimensional integrative approach to psychopathology focus on factors from genetics and neuroscience
BIOLOGICAL
___ dimensions of the multidimensional integrative approach to psychopathology focus on factors from behavioral and cognitive processes
PSYCHOLOGICAL dimensions. includes learned helplessness, social learning, etc.
____ influences of the multidimensional integrative approach to psychopathology focus on social factors
interpersonal dimensions
_____ influences of the multidimensional integrative approach to psychopathology focus on age-related factors and critical period influences
DEVELOPMENTAL
a one dimensional model is ___ in approach and attributes causes of behavior to:
a one dimensional model is LINEAR in appraoch and attributes causes of behavior to a SINGLE CAUSE
______ model encompases 2 or more influences.
multidimensional model.
a normal human cell has ___ chromosomes arranged in __- pairs.
a normal human cell has 46 chromosomes arranged in 23 pairs.
most of our development and behaviour is polygenic, meaning:
it is influenced by many genes, which also may be influenced by the environment.
genome
an individuals complete set of genes
quantitative genetics
estimates the effects of genes on individual differences.
molecular genetics and a technique used
actual structure and functioning of genes.
-DNA microarrays: identify gene networks that may be contributing to a particular trait.
briefly describe the interaction of genetic and environmental effects
- genetic structure of the cell may actually change as a result of learning. the environment may occasionally turn genes on. the receptor activation may change, resulting in dif biochemical functioning in the brain.
diathesis stress model
individuals inherit from multiple genes tendencies to express certain traits and behaviors.
- when the right kind of life event occurs (stress), a disorder may develop due to predisposition
what is a diathesis
an inherited tendency/condition that makes a person susceptible to developing a disorder.
gene-environment correlational method/hypothesis
the idea that genetic endowment may increase probability of responding negatively to stressful events . people with genetically determined tendencies may create the very environmental risk factors that trigger a genetic vulnerability to the disorder.
describe the anxious rat pup study and its relevance to epigenetics and critical periods.
studied epigenetics. rats born to an anxiousmom but raised with non-anxious moms grew up more calm than their siblings who were raised by the anxious mom.
- this effect occurred only if the rat mother was calm during the rat pups’ first week of lfie. Early experiences is important —> Critical Period.
- study suggests t environmental effects of early parenting seem to OVERRIDE any genetic contribution to be anxious, emotional, or reactive to stress.
- anxious born but nonanxious raised rats were also calm when raising their own young, therefore, reversing the genetic contribution to the expression of personality traits.
epigenetics
genes are turned on/off by cellular material that is located just outside of the genome. stress, nutrition, and other factors can affect this epigenome.
- the genome isn’t truly changes, but the type of genome expressed can change depending on the disappearance/appearance of stress.
-strong environmental influences may be sufficient to override genetic diatheses.
the CNS is comprised of the ___ and __ ___
brain and spinal cord.
neurons are connected with each other by a ___ ___ and communicates using ___ ___
connected by a SYNAPTIC CLEFT and communicates using NEUROTRANSMITTERS
two main “structures” of the brain
1) brain stem: handles essential automatic functions: breathing, sleeping, coordinated movement etc.
2) forebrain
5 regions of the brainstem
1) hind brain
2) midbrain
3) thalamus and hypothalamus
4) limbic system
5) basal ganglia.
3 primary structures of the hindbrain and purpose
Medulla, Pons, Cerebellum.
- automatic regulation: heart beat, disgestion, motor (cerebellum), breathing.
structures of the midbrain and the purpose
contains the RETICULAR ACTIVATING SYSTEM:
1) superior colliculus
2) inferior colliculus
3) pineal galnd.
coordinates movement with sensory input. also involved with arousal and tension
purpose of thalamus and hypothalamus
broad regulation of behavior and emotion. relay structures between forebrain and lower brainstem.
structures of the limbic system and pupsoe
1) hippocampus
2) cingulate gyrus
3) septum
4) amygdala.
- regulates emotional experiences and expressions. involved in basic drives of sex, aggression, hunger and thirst.
what nucleus is associated with the basal ganglia?
caudate nucleus. the basal ganglia and caudate nucleus are involved in motor activity.
the forebrain’s cerebral cortex is divided into ___ hemispheres that operate relatively independently. differences between the hemispheres?
2 hemispheres.
right hemisphere: creating images
left hemisphere: verbal and cognitive processess
which lobe is responsible for long term memory storage
temporal
which love is responsible for reasoning abilities and memory, sociality, relation
frontal lobe
two branches of autonomic NS
symp and parasymp
symp ganglia are near the ____, parasymp ganglia are near the ___
symp ganglia are near the SPINAL CORD, parasymp ganglia are near the EFFECTOR ORGAN
preganglionic axons use ____, post ganglionic axons use ___ in symp and ____ in parasymp
preganglionic axons use ACH, post ganglionic axons use NE in symp and ACH in parasymp
the endocrine system is regulated by the ____ nervous system.
PARASYMPATHETIC nervous system. contains glands that each produce its own hormones, which are released into the blood stream.
3 consequences of sympathetic nervous system actvation
1) increased HR: increased blood flow to muscle
2) increased respiration: increased O2 to body
3) adrenal gland stimulation.
the ______ (in brain stem) connects to the ___ gland, which regulates the endocrine system. the ___ gland may stimulated the ___ adrenal gland, which causes the production and release of ___ and ____. This entire system is known as the ___ axis.
the HYPOTHALAUS (in brain stem) connects to the PITUITARY gland, which regulates the endocrine system. the PITUITARY gland may stimulate the CORTICAL adrenal gland, which causes the production and release of CORTISOL and NE This entire system is known as the HYPOTHALAMIC-PITUITARY-ADRENALCORTICAL axis.
T/F: disturbances in funcitoniong are almost never involving problems with a single neurotransmitter
true. they almost always involve various neurotransmitters.
most NTs are ___ or ___ ____
monoamines or amino acids.
____ increase the activity of NT by mimicking its effects
____ decrease the activity of NT by blocking the receptor
____ ____ produce the effects opposite to those produced by the NT
AGONIST increase the activity of NT by mimicking its effects
ANTAGONIST decrease the activity of NT by blocking the receptor
INVERSE AGONIST produce the effects opposite to those produced by the NT
___ and ___ are chemical brothers because they work to balance brain function.
glutamate and GABA
how do benzodiazepines have relaxing effects
makes it easier for GABA molecules to attach themselves to specific receptors. therefore, they are GABA agonists because they increase binding. The more benzodiazepines, the more GABA becomes attached to neuron receptors and the calmer we become
- reduce anxiety and aggression
- possible anti-convulsant effects.
what structure is involved in the 5HT system? what does it do?
dorsal raphe nuclei. it regulates our moods and thought processes. decreased 5HT may result in increased impulsivity, instability, suicide, impulsive overeating, depression.
what happens when you have wayyy too much 5HT?
may interact with GABA to counteract glutamate
NE receptors
alpha and beta. beta is seen in the parasymp NS. Beta blockers results in decreased HR and decreased BP.
2 circuits of NE
1) alarm circuit: influences emergency reactions
2) hindbrain circuit: basic bodily function (ex/ respiration rate)