Chapter 18 - Acne Flashcards

1
Q

What is ance and how does it develop?

A
  • Acne is a disease of the sebaceous hair follicle
  • Sebum is trapped within the follicle unlike normal circumstances where sebum produced by sebaceous glands travels up the hair follicle and out onto the skin surface.
  • Acne develops on areas of the skin where sebaceous glands are most numerous.
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2
Q

What is the common/ordinary acne called?

A

Acne vulgaris

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3
Q

What are the 4 basic factors for the development of acne?

A

(1) Hormones (androgens)
(2) Increased sebum production
(3) Changes inside the follicle
(4) Bacteria

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4
Q

How does hormone aid the development of acne?

A
  • Acne begins when the body starts to produce hormones (androgens) at about age 11 to 14 years
  • Androgens cause sebaceous gland to enlarge
  • Acne develops when sebaceous glands are over-stimulated by androgens
  • Young women have acne flare-ups that coincides with hormonal changes associated with their menstrual cycle.
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5
Q

How does increased sebum production aid the development of acne?

A
  • Androgens stimulate sebaceous gland causing more sebum to be produced.
  • Sebum accumulates in the follicle
  • Sebum travels up the hair follicle and mixes with normal skin bacteria and dead skin cells
  • Greater sebum production, greater the likelihood the follicle will get clogged.
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6
Q

How does changes inside the follicle aid the development of acne?

A
  • As androgen production increases, sebaceous glands enlarge
  • Dead cells inside the follicle shed gradually and are expelled onto the surface.
  • During puberty, these cells shed more rapidly and tend to stick together
  • When the cells mix with sebum, they can clog the follicle
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7
Q

How does bacteria aid the development of acne?

A
  • Clogged follicle becomes a breeding ground for bacteria
  • One type of bacteria specifically involved is Propionibacterium acnes or P. acnes (Normal resident on the skin which ingests the sebum)
  • Follice gets clogged and sebum builds ups inside causing P. acnes to multiply rapidly
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8
Q

How are acne lesions generally defined?

A

1) Size

2) Inflammatory/ non- inflammatory

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9
Q

What are the 2 types of non-inflammatory lesions and what are the general difference between them?

A

(1) Open comedones (Blackheads)
- Contents of the follicle are firmly impacted inside
- Tightly compacted cells and sebum give the follicle its ‘black’ appearance
(2) Closed comedones (Whiteheads)
- White or skin-coloured, small bumps on or under the skin.

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10
Q

What are the 3 types of inflammatory acne lesions?

A

(1) Papules
(2) Pustules
(3) Nodules
- Have a red colour, often making a ring around the pimple itself.
- Result when sebaceous materials from the comedo get into the surrounding tissue and cause an inflammatory reaction

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11
Q

Describe the genetic connection of acne.

A

Similarities in acne among family members regarding the types of acne lesions, duration of acne, severity of acne

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12
Q

How can cosmetics cause acne?

A
  • May be caused by ingredients that clog pores. (known as comedogenic)
  • Should look for non-comedogenic cosmetics and toiletries.
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13
Q

Describe the susceptibility of the public to acne.

A
  • Close to 100% of age 12-17 have at least an acne lesion
  • Most are able to manage with over-the-top counter treatments.
  • Usually occurs between age 11 to 14 and usually last 5 to 10 years. Normally disappears in early 20s
  • Young men more likely to have more severe, longer lasting forms of acne
  • Young women are more likely to have intermittent acne due to the hormonal changes associated with menstrual cycle and acne caused by cosmetics
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14
Q

Describe the process and types of scars from acne.

A
  • Scarring because acne is a skin disease and skin responds by repairing it
  • Repair can produce a scar that looks like a pit in the skin.
  • Red mark on skin called an erythematous macule will fade in 4-6 months after an acne outbreak (red macule not a scar)
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15
Q

When should you seek professional advice for acne lesions?

A
  • Tried OTC products but does not work.
  • Acne interferes with enjoyment of life
  • Acne scars in addition to acne lesions
  • Acne lesion are large and painful
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16
Q

How can acne be treated?

A

By preventing its development.

  • Reduce P.acnes
  • Unplug clogged pores
  • Reduce sebum production
17
Q

What are the general guidelines for acne care?

A
  • Do not pop, squeeze or pick at acne
  • Gently wash your face twice a day with a gentle cleanser that has pH of around 5.5. (Vigorous washing and scrubbing can irritate your skin
  • After washing use appropriate acne products
  • Style hair so that it does not directly touch the forhead and face. (Keep items that directly touch the face and hair very clean)
  • Acne products can increase the skin’s sensitivity to sunlight. Use protective clothing and sunscreens, and avoid tanning booths
  • Reduce stress associated with over-work
18
Q

What are the 3 main functions in acne products and name examples of ingredients from each?

A

(1) Antibacterial - Benzoyl peroxide, sulfur, tea tree oil
(2) Exfoliating - Salicylic acid, glycolic acid, lactic acid
(3) Comedolytic - Benzoyl peroxide, tretinoin (drug)

19
Q

What is HPMC used for?

A

Viscosity controlling agent