Chapter 13 - Roles of Fragrances/Fragrance Ingredients; Fragrance Ingredients - Safety Aspects Flashcards

1
Q

What are the roles of fragrances?

A
  • Influence consumer purchases
  • Mask odours
  • Actual functionality
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2
Q

How do fragrances affect consumer purchases?

A

1) Support product’s function
- Anti-dandruff shampoo - ‘Medicinal smell’
- Baby shampoo - ‘Gentle, soft’ scent
2) Emphasise specific imagery
- Suntan oil products - Coconut scent for tropical holiday theme
3) Emphasise presence of specific ingredients
- Honey moisturizing shampoo - Honey scent
- Tea tree oil shampoo - Tea tree oil scent

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3
Q

How do fragrances help mask odours?

A

1) To alter the product’s smell (Some raw materials inherently have unpleasant odour)
- Thiol compounds in permanent hair-waving products
- Fats and waxes (thickeners, surfactants and emulsifiers) in some skin or hair care products
2) To produce ‘unscented’ products
- Finished product with minimal smell

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4
Q

How do fragrances help achieve its actual functionality?

A

Certain essential oils, such as thyme oil have antimicrobial properties

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5
Q

Define the terminologies ‘hazard’, ‘risk’ and ‘risk assessment’.

A

1) Hazard:
- Potential to cause injury
- Intrinsic properties
- No relation to dose/exposure
2) Risk:
- Probability of harm
- Relation with exposure
3) Risk assessment:
- Evaluates potential of a material to cause harm
- How likely this potential is reached during normal-use condition

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6
Q

What does ‘safety’ mean in cosmetics?

A
  • Relative term that can only estimate probability of harm

- Judgement that a particular exposure to a substance has either no foreseeable risk of harm, or negligible risk

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7
Q

What is the difference between a medicine and a poison?

A

The dose given

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8
Q

What are the 6 components relating to risk assessment?

A

1) Hazard identification
2) Dose-response
3) Exposure assessment
4) Risk characterization
5) Risk management
6) Risk communication

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9
Q

What are the 2 main international fragrance organizations that practice self-regulation?

A

1) International Fragrance Association (IFRA)

2) Research Institute for Fragrance Materials (RIFM)

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10
Q

What is defined according to the IFRA standards?

A

Define safe use levels for individual fragrance ingredients

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11
Q

According to the IFRA standards, what is the difference between ‘Prohibited’, ‘Restricted’ and ‘Specification’?

A

Prohibited - Material cannot be used as a fragrance ingredient
Restricted - Use of the material should be limited quantitatively
Specification - Purity criteria for the materials should be adhered to.

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12
Q

What is fragrance on skin evaluated as?

A

Exposure route

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13
Q

Describe what is skin irritation.

A

Redness (erythema) and/or swelling (oedema):
- Usually disappears after irritant removed
Most fragrance ingredients:
- Mild or moderate irritants when in undiluted forms
- Low levels in consumer products

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14
Q

What is skin sensitization?

A

Some ingredients may penetrate through skin causing immune response (allergic contact dermatitis)
Usually appears some time after contact
More severe upon subsequent exposure

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15
Q

How does photoeffects cause skin sensitization?

A

Some coumarin derivatives cause skin sensitization when exposed to sunlight (E.g 7-methoxycoumarin)

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16
Q

What are the natural phototoxic ingredients in citrus peel oils called?

A

Furocoumarins

E.g (bergaptene/ 5-methoxypsoralen)

17
Q

Who regulates the cosmetic products in Singapore?

A

Health Sciences Authority (HSA)

18
Q

What are the legislations related to HSA?

A
Health Products (Cosmetic Products - ASEAN Cosmetic Directive) Regulations 2007
Health Products Act (Amendment of First Schedule) (No.2) Order 2007
19
Q

When was the ASEAN Cosmetic Directive (ACD) effective and what was new?

A

January 2008
Under the ASEAN Harmonized Cosmetic Regulatory Scheme, one standard scheme for regulating cosmetic products in ASEAN countries

20
Q

What are the ASEAN guidelines for safety assessment of cosmetics?

A

Composition of fragrances generally not available to cosmetics manufacturer, adequate information on fragrance safety to be provided by raw material supplier.

  • Certificate of compliance to the latest IFRA guidelines
  • Maximum safe concentration depending on product type
21
Q

What is Appendix II of the ACD?

A

Cosmetic labelling requirements

- Full ingredient listing

22
Q

What is the difference between the ACD and EU fragrance ingredient labelling?

A

ACD - Perfume/Fragrance

EU - Parfum/aroma

23
Q

How can fragrance ingredient labelling for cosmetic product aid in risk communication?

A
  • Ensure fragrance-sensitive consumers are adequately informed about the presence of these ingredients in cosmetic products
  • Improve diagnosis of contact allergies in such consumers