Chapter 15- The Chromosomal Basis Of Inheritance Flashcards

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1
Q

The chromosome theory of inheritance states:

A

Mendelian genetics have specific loci on chromosomes

Chromosomes undergo segregation and independent assortment

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2
Q

Fruit flies have how many pairs of chromosomes?

A

4

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3
Q

Morgan determine that the white eyed mutant allele must be located on the…

A

X chromosome

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4
Q

Gene On the Y chromosome codes for a protein that directs the development of male anatomical features

A

SRY gene

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5
Q

sperm either contains an ____ or _____ chromosome

A

X, Y

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6
Q

A gene that is located on either sex chromosome is called a

A

Sex-linked gene

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7
Q

_____ chromosomes have genes for many characters unrelated to sex, where as the ______ chromosome mainly encodes genes related to sex determination

A

X, Y

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8
Q

For A recessive X linked trait to be expressed, a female needs……
And a male needs……

A

Two copies of the allele

One copy (hemizygous)

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9
Q

X linked recessive genedisorders are much more common in

A

Males

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10
Q

If a female is heterozygous for a particular gene located on the X chromosome she will be a ________ for that character

A

Mosaic

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11
Q

In mammalian females, one of the two X chromosomes in each cell is randomly inactivated during embryonic development, the inactive X condenses into a….

A

Barr Body

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12
Q

Each chromosome has ___________ genes (except theY chromosome)

A

Hundreds or thousands of genes

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13
Q

What ratios do you see for traits on the same chromosome vs. different chromosomes?

A

Different chromosomes 1:1:1:1

Same chromosome 1:1:0:0

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14
Q

What did Morgan find that was usually inherited together? (Parental phenotypes)
They did not sort independently because they were

A

Body color and Wing size

On the same chromosome

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15
Q

Offsprings with a phenotype matching one of the parental phenotypes are called

A

Parental types

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16
Q

A ______% Frequency of recombination is observed for any two genes on different chromosomes

A

50

17
Q

If the number of recombinations is below 50% it is….

A

One the same chromosome (linked)

18
Q

Who created the genetic map?

A

One of Morgan’s students, Alfred Sturtevant

19
Q

What is an ordered list of the genetic loci along a particular chromosome

A

Genetic map

20
Q

A genetic map of a chromosome based on recombination frequencies

A

Linkage map

21
Q

Distance between genes can be expressed as what units?

A

Map units

One map unit Represents a 1% recombination frequency

22
Q

How do you calculate map distance?

A

Number of recombinants
Divided by
Total number of offspring

x100

23
Q
  • pairs of homologous chromosomes do not separate normally during meiosis
  • as a result, one gamete received two of the same type of chromosome and the other game he receives no copy
A

Nondisjunction

24
Q

This results from the fertilization of gametes in which non-disjunction occurred

Offspring has an abnormal number of a particular chromosome

A

Aneuploidy

Monosomic- zygote has one copy of a particular chromosome

Trisomic- zygote has three copies of a particular chromosome

25
Q

Is a condition in which an organism has more than two complete sets of chromosomes

A

Polyploidy

This is common in plants

26
Q

What causes “cry of the cat”?

A

Deletion in chromosome 5

27
Q

CML leukemia is caused by what?

A

Translocations of chromosomes

28
Q

What is it called when the phenotype depends on which parent passed along the alleles for those traits?
Involves the silencing of certain genes that are “stamped” with an imprint during gamete production

A

Genomic imprinting

They can have the same genotype but the phenotype is different

Methylation makes it inactive