Chapter 15 (Microbial Mechanisms of Pathogenicity) Flashcards
All of the microbes that are associated with a certain organism or environment =
Microbiome
Microbes that come in contact with your body but can’t establish themselves there long-term; often include pathogens =
Transient Microbiota
The microbes that constantly live on one’s body =
Resident Microbiota
Cause disease in the host in almost every case =
Primary Pathogen
Can only cause disease in the host in certain situations =
Opportunistic Pathogen
What specific situations can an opportunistic pathogen affect you?
When your immune defense are weaker, if the host is introduced to a new environment, when bacteria that normally live in the mouth get into a cut in the gums and cause an infection
Condition where the normal structure/functions of the body are damaged/impaired =
Disease
How can diseases be classified?
Taxonomic Categories
The body system they effect
Their longevity + severity
How they are spread to their host
The effects they have on populations
Subjective characteristics of disease felt only by the PT =
Symptoms
Objective manifestations of disease observed or measured by others =
Signs
Infections lack symptoms but may still have signs of infection =
Asymptomatic or Subclinical
Symptoms develop rapidly; runs its course quickly =
Acute Disease
Usually has mild symptoms that develop slowly and last a long time =
Chronic Disease
Disease without symptoms =
Asymptomatic Disease
Disease that appears a long time after infection =
Latent Disease
Can be transferred to one another =
Communicable Disease
A communicable disease that is easily spread =
Contagious Disease
Disease that can’t be spread from person to person =
Noncommunicable Disease
Initial infection within a given PT =
Primary Infection
Infections that follow a primary infection; often opportunistic pathogens =
Secondary Infection
Many infectious diseases have how many stages following an infection?
5
What are the 5 stages following an infection?
Incubation Period, Prodromal Period, Illness, Decline, Convalescence
Can infectious diseases be contagious during any period of the five stages?
Yes, but it depends on the pathogen and the nature of the disease
Interval between initial infection and first signs and symptoms =
Incubation Period
Short period after incubation; early, mild symptoms =
Prodromal Periods
Disease is most severe =
Period of Illness
Signs and symptoms subside =
Period of decline
Body returns to its pre-diseased state =
Period of Convalescence
The manner of developing a disease =
Pathogenesis
What are the 5 steps of pathogenesis in order?
Exposure/Contact
Adhesion
Invasion
Infection
Transmission
Pathogen gains entry to the host =
Exposure/ Contact
Pathogen colonizes the host =
Adhesion
Pathogen evades/ overcomes host immune response =
Invasion
Pathogen spreads, multiplies + causes damages to the host =
Infection
Pathogens leave the original host to infect new susceptible host =
Transmission