Ch 24 Digestive System Infections Flashcards
The digestive system structure is divided into what 2 groups?
Gastrointestinal Tract
Accessory Digestive Organs
The pathway from the mouth to the anus =
GI Tract
Organs involved in grinding food or providing digestive secretions =
Accessory Digestive Organs
The tongue, teeth, and salivary glands are all-
Accessory Digestive Organs
The liver, gallbladder, and pancreas are all-
Accessory Digestive Organs
The esophagus, stomach, and duodenum are all-
Almost free of any microbes
What prevents microbial colonization in the esophagus, stomach, and duodenum?
Peristalsis + the rapid transport of food
What’s the most prevalent microbe on the tongue, teeth, jejunum, ileum, colon, and rectum?
Species of Streptococci
The microbiota in the lower small intestine and colon are-
Microbial Antagonists
The microbial antagonists in the lower small intestine and colon do what for the body?
Protect the body by outcompeting pathogens.
Produce vitamins, folic acid, biotin, and vitamin K.
The mucous membrane does what for the body?
Prevents entry of microbes into the blood stream
Erosions of the linings of either the stomach or small intestine =
Peptic Ulcers
Ulcers that pierce the stomach or intestine are called-
Perforations
A Perforation can cause-
Shock
Abdominal pain is the main symptom of-
Peptic Ulcers
Signs and symptoms of Peptic Ulcers includes:
Abdominal Pain
Nausea
Vomiting (With or Without Blood)
Weight Loss
Burping
Loss of Appetite
Chest Pain
Black Tarlike Stools
Peptic Ulcers are caused by what bacteria?
Helicobacter pylori
How does H. pylori cause Peptic Ulcers?
It invades mucous, its toxins and inflammation cause the layer of mucous to become thin, gastric acid then destroys the epithelial tissue and underlying tissue (Causing an ulcer)
How many people develop Peptic Ulcers per year?
456,000
How much of the population is infected by Peptic Ulcers?
2 thirds of the population
What are some risk factors for Peptic Ulcers?
Aspirin, Ibuprofen, Excessive Alcohol Consumption, Smoking, Family History
What can worsen Ulcer symptoms?
Stress
How can you diagnose Peptic Ulcers?
X-ray to identify Ulcers
Presence of H. pylori in stool
Inflammation of stomach or intestines caused by bacteria =
Bacterial Gastroenteritis
Bacterial Gastroenteritis is associated with-
Contaminated food or water and poor living conditions/lack of sanitation
What are the manifestations of Bacterial Gastroenteritis?
Nausea + Vomiting + Abdominal Pain + Cramps + Malaise + Fever + Dehydration
Treatment of Bacterial Enteritis includes-
Fluid and electrolyte replacement
Most E. coli Gastroenteritis are-
Harmless, but others can cause severe diarrheal illnesses
How does E. coli Gastroenteritis spread?
Contaminated food/water, direct contact with animals/people
What are the risk groups for E. coli Gastroenteritis?
Elderly, Pregnant, Immunocompromised, and Travelers
What are some symptoms of Enterotoxigenic E. coli (ETEC)?
Causes Traveler’s Diarrhea (Common in less developed countries).
It is a relatively mild condition that is self-limiting.
What’s the most dangerous types of E. coli that can cause epidemics?
Enterohemorrhagic E. coli (EHEC)
Manifestations of EHEC are-
Bloody Diarrhea, Severe Cramping, No Fever
EHEC produces a toxin called-
Verotoxin
Verotoxin can cause-
Hemolytic Uremic Syndrome (HUS)
What is HUS?
A type of kidney failure
How can EHEC be diagnosed?
Presence of Verotoxin Genes
Salmonella enterica lives in-
The intestines of virtually all vertebrates, especially reptiles and are eliminated in feces
Can S. enterica be a part of the normal microbiome of some humans?
Yes
How many unique strains of Salmonella are there?
How many species?
2,100 Unique Strands
Just 1 Species (Salmonella enterica)
What strains of Salmonella can cause Salmonellosis?
Enteritidis and Typhimurium
How does Salmonella spread?
Via contaminated food (usually eggs and poultry) and water, direct animal contact, rarely person to person
How does Salmonellosis occur?
Salmonella passes through intestinal cells into the bloodstream where they are phagocytized.
Salmonella can survive phagocytosis, and therefore becomes disseminated throughout the body.
Disruption of the intestinal cells can cause-
Tissue damage and inflammation leading to fluid leakage and diarrhea
Symptoms of Salmonellosis develop within how long after infection?
6-4 Hours
Patients with Salmonellosis experience-
Fever + Headache + Muscle Pain + Loss of Appetite for a week or more
How do you diagnose Salmonellosis?
Finding Salmonella in stool
Symptoms of salmonellosis develop within how long after infection?
6 hours to 4 days