Chapter 14 Flashcards

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1
Q

axillary nodes

A

lymph nodes in the armpit

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2
Q

B cell (B lymphocytes)

A

Lymphocyte that matures into a plasma cell to secrete antibodies. The B refers to the bursa of Fabricius, an organ in birds in which B cell differentiation and growth were first noted to occur.

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3
Q

cell-mediated immunity

A

T cells (cytotoxic, helper T and suppressor) that respond to antigens and destroy them; a type of adapted immunity

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4
Q

cervical nodes

A

lymph nodes in the neck region

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5
Q

complement system

A

proteins in the blood that help antibodies kill their target

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6
Q

cytokines

A

proteins secreted by cytotoxic T cells to aid in antigen destruction. Examples are interferons and interleukins

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7
Q

cytotoxic T crll

A

lymphocyte that directly kills antigens; called CD8-positive T cell

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8
Q

dendritic cell

A

antigen-presenting cell. Shows T and B cells what to attack.

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9
Q

helper T cell

A

lymphocyte that aids B cells and stimulates T cells. Also called CD4-positive T cell

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10
Q

humoral immunity

A

B cells produce antibodies after exposure to specific antigens; type of adaptive immunity

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11
Q

immunity

A

Body’s ability to resist foreign organisms and toxins that damage tissues and organs. This includes immunity and adaptive immunity.

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12
Q

immunoglobulins

A

antibodies secreted by plasma cells (mature B cells) in response to the presence of an antigen

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13
Q

immunotherapy

A

use of immune cells, antibodies, or vaccines to treat or prevent disease.

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14
Q

inguinal nodes

A

lymph nodes in the groin region

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15
Q

interferons

A

proteins (cytokines) secreted by T cells and other cells to aid and regulate the immune response.

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16
Q

interleukins

A

proteins (cytokines) that stimulate the growth of B and T lymphocytes

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17
Q

interstitial fluid

A

fluid in the spaces between cells. This fluid becomes lymph when it enters lymph capillaries.

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18
Q

lymph

A

thin, watery fluid found within lymphatic vessels and collect from tissues throughout the body.

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19
Q

lymph capillaries

A

tiniest lymphatic vessels

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20
Q

lymphoid organs

A

lymph nodes, spleen, and thymus gland

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21
Q

lymph node

A

collection of stationary solid lymphatic tissue along lymph vessels; contains cells (lymphocytes and macrophages) that fight infection.

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22
Q

lymph vessel

A

Carrier of lymph throughout the body; lymphatic vessels empty lymph into veins in the upper part of the chest

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23
Q

macrophage

A

large phagocyte found in lymph nodes and other tissues of the body.

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24
Q

mediastinal nodes

A

lymph nodes in that area between the lungs in the thoracic cavity

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25
Q

mesenteric nodes

A

lymph nodes in the mesentery (intestinal region)

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26
Q

functions of the spleen

A

Destruction of old erythrocytes by macrophages
Filtration of microorganisms and other foreign material from the blood
Activation of lymphocytes
Storage of blood

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27
Q

monoclonal antibody

A

antibody produced in a laboratory to attack antigens and to destroy cells; useful in immunotherapy

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28
Q

natural immunity

A

protection that an individual is born with to fight infection such as neutrophils, monocytes, macrophages, and NK cells. It is not antigen specific and does not elicit memory.

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29
Q

paraaortic nodes

A

lymph nodes near the aorta in the lumbar (waist) area of the body.

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30
Q

plasma cell

A

lymphocyte that secretes antibodies. It matures from B lymphocytes

31
Q

right lymphatic duct

A

lymphatic vessels in the chest that drains lymph from the upper right part of the body, Ig empties lymph into large vein in the neck

32
Q

spleen

A

organ in the upper quadrant of the abdomen that destroys worn-out ref blood cells, activates lymphocytes, and stores blood

33
Q

suppressor T cell

A

lymphocyte that inhibits the activity of B and T cells. Also called a Treg (regulatory T cell)

34
Q

T cell ( T lymphocyte)

A

Lymphocyte that acts directly ok antigens to destroy them or produce chemicals (cytokines) such as interferons and Interleukins that are toxic yo antigens

35
Q

tolerance

A

the ability of T lymphocytes to recognize and accept the body’s own antigens as “self” or friendly. Once tolerance is established, the immune system will not react against the body.

36
Q

thoracic duct

A

large lymphatic vessel that drains lymph from the lower and left side of the body (head, neck, arm, and chest). It empties lymph into large veins in the neck

37
Q

thymus gland

A

lymphoid organ in the mediastinum that conditions T cells to react to foreign cells and aids in the immune response.

38
Q

tonsils

A

masses of lymphatic tissue in the back of the oropharynx

39
Q

toxin

A

poison; a protein produced by certain bacteria, animals, or plants.

40
Q

vaccination

A

exposure of an individual to a foreign protein (antigen) that provokes an immune response. The response will destroy any cell that posses the antigen on its surface and will protect against infection.

41
Q

vaccine

A

weakened or killed microorganisms, toxins m, or other proteins given to induce immunity to infection or disease

42
Q

immun/o

A

protection

43
Q

lymph/o

A

lymph

44
Q

lymphaden/o

A

lymph node (gland)

45
Q

splen/o

A

spleen

46
Q

thym/o

A

thymus gland

47
Q

tox/o

A

poison

48
Q

ana-

A

again, anew

49
Q

inter-

A

between

50
Q

severe combined immunodeficiency disease (SCID)

A

an immunodeficiency disorder presented at birth. Affected infants are born with a deficiency of B cells and T cells, resulting in a lack of immunity

51
Q

acquired immunodeficiency syndrome (AIDS)

A

group of clinical signs and symptoms associated with suppression of the immune system and marked by opportunistic infections, secondary neoplasms, and neurologic problems

52
Q

all/o

A

other

53
Q

allergy

A

abnormal hypersensitivity acquired by exposure to an antigen.

54
Q

lymphoma

A

malignant tumor of lymph nodes and lymph tissue

55
Q

hodgkin disease

A

malignant tumor of lymphoid tissue in the spleen and lymph nodes

56
Q

multiple myeloma

A

malignant tumor of bone marrow

57
Q

thymoma

A

malignant tumor of the thymus gland

58
Q

allergen

A

substance capable if causing a specific hypersensitivity reaction in the body; a type of antigen

59
Q

anaphylaxis

A

exaggerated or unusual hypersensitivity to foreign protein or other substance.

60
Q

atopy

A

hypersensitive or allergic state involving an inherited predisposition.

61
Q

CD4 + cells

A

Helper T cell that carry the CD4 protein antigen on their surface. HIV binds to CD4 and infects and kills T cells bearing this protein. AIDS patients have an inadequate number of CD4+ cells.

62
Q

HIV

A

virus (retrovirus) that cause AIDS

63
Q

kaposi sarcoma

A

malignant lesion associated with AIDS; arises from the lining of capillaries and appears as red, purple, brown, or black skin nodules.

64
Q

non-Hodgkin lymphomas

A

group of malignant tumors involving lymphoid tissue.

65
Q

opportunistic infections

A

infectious diseases associated with AIDS; they occur because HIV infection lowers the body’s resistance and allows infection by bacteria and parasites that normally are easily contained

66
Q

protease inhibitor

A

Drug that treats AIDS by blocking the production of protease, a proteolytic enzyme that helps create new viral pieces for HIV

67
Q

reverse transcriptase inhibitors (RTI)

A

drug that treats AIDS by blocking reverse transcriptase, an enzyme needed to make copies of HIV.

68
Q

wasting syndrome

A

weight loss, disease in muscular strength, appetite, and mental activity; associated with AIDS

69
Q

CD4+ cell count

A

measures the number of CD4+ T cells (helper T cells) in the bloodstream of patients with AIDS

70
Q

ELISA

A

screening test to detect anti-HIV antibodies in the bloodstream

71
Q

immunoelectrophoresis

A

test that separates immunoglobulins

72
Q

viral load count

A

measurement of the amount of AIDS virus (HIV) in the bloodstream

73
Q

computed tomography (CT) scan

A

x-rat imaging produces cross-sectional and other views of anatomic structures