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Microbiology > Chapter 13 > Flashcards

Chapter 13 Flashcards

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Biology 101 flashcards
1
Q

3 diseases caused by Chlamydial infection

A

Chlamydial urethritis, Lymphogranuloma venereum, Trachoma

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2
Q

3 diseases caused by Ricketsial infection

A

Rochey mountain spotted fever, Q fever, Typhus Fever

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3
Q

What kind of parasite is Chlamydiae

A

obligate intracellular parasites

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4
Q

Can Chlamydiae make their own ATP

A

NO

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5
Q

What does Chlamydiae infect?

A

epithelial cells of skin and mucous membranes

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6
Q

Chlamydiae replication cycle

A

spore like metabolically inert Elementary bodies enter the cell, become metabolically active, reticulate body, undergo repeated binary fission, burst and release daughter elementary body

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7
Q

3 types of Chlamydiae

A

Ch. Psittaci, Ch. Pneumoniae, Ch. Trachomatis

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8
Q

How do you get a Ch. Psittaci infection?

A

bird’s disease- inhalation of dried bird’s feces causes human infection, fever and pneumonia

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9
Q

How do you get a Ch. Pneumoniae infection?

A

communicable by aerosol- causes a typical pneumonia in humans

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10
Q

How do you get a Ch. Trachomatis infection?

A

only in humans- causes trachoma, genital tract infection, lymphogranuloma venereum

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11
Q

What is trachoma?

A

chronic infection of conjunctival mucous membrane- common in Africa and Asia- transmitted by fomites and fingers

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12
Q

Who is trachoma highly contagious in?

A

children- transmitted by fomites and fingers

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13
Q

What does late stage trachoma cause?

A

scarring of conjunctiva and opacities in cornea resulting in blindness

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14
Q

What does Type D-K chlamydiae cause?

A

STD of infection through birth canal- world wide distribution- occurs in higher socio-economic group

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15
Q

What does Chlamydial infection cause in new borns?

A

acute purulent conjunctivitis

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16
Q

What does Chlamydial infection cause in adult males?

A

urethritis which may progress to epidedymitis, proctitis or prostitis

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17
Q

What does Chlamydial infection cause in adult women?

A

causes cervicitis (inflammation of cervix) may progress to salphingitis @ PID often sterility/ectopic gestation

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18
Q

What syndrome may patients with genital tract infection develop?

A

Reiter’s Syndrome

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19
Q

What does Ch. Trachomatis L group cause?

A

lymphogranuloma venereum (LGV)

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20
Q

What does LGV cause?

A

painful ulcers on genitals with inguinal node enlargement, no immunity

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21
Q

Lab diagnosis of chlamydial infection?

A

cause characteristic inclusion bodies in cells- Giemsa stain is used to stain urethral/conjunctival smears to demonstrate infection

22
Q

Tests for lab diagnosis of chlamydial infection?

A

immunolflourescent test, DNA probe, ELISA

23
Q

What treatment are all chlamydial infections susceptible to?

A

TC/ Doxy

24
Q

Treatment of chlamydial infection STDS

A

Azithromycin

25
Q

Treatment of Chlamydial ophthalmia neonatorum

A

Erythromycin

26
Q

Prevention for Chamydia

A

no vaccination, erythromycin drops for new borns

27
Q

Define Reiter’s syndrome

A

an autoimmune condition that develops in response to an infection in a part of the body

28
Q

Symptoms of Reiter’s Syndrome

A

an inflammatory arthritis of large joints, inflammation of the eyes, urethritis

29
Q

How is reactive arthritis (reiters syndrome) transmitted?

A

transmitted through sexual transmitted diseases

30
Q

Define Ricketsiae

A

obligate intracellular organisms, lack co enzyme A, NAD, ATP

31
Q

How is Ricketsiae transmitted?

A

arthropod bite

32
Q

Q fever is caused by what organism?

A

Coxiella burnetti

33
Q

What animals is Q fever present in?

A

cattle, sheep, goat- but they do not suffer from disease

34
Q

What is Q fever spread by?

A

animals, amniotic fluid, placenta, urine and feces, aerosol- inhalation even miles from product

35
Q

symptoms of Q fever?

A

flu like symptoms, pneumonia, hepatitis - acute infection, no rash

36
Q

What is rocky mountain spotted fever caused by?

A

ricketti- spread by dog tick

37
Q

Symptoms of rocky mountain spotted fever?

A

flu like symptoms, papulo macular rash, hemorrhages on hand and feet then to trunk, –head ache, delirium, coma in severe cases

38
Q

What is the reservoir and vector of rocky mountain fever?

A

ticks– humans are accidental host– common in children in the spring and early summer

39
Q

3 types of typhus fever

A

epidemic typhus, endemic typhus, scrub typhus

40
Q

What is epidemic typhus spread by?

A

human louse

41
Q

Causative organism of epidemic typhus

A

Ricketsiae Prowazaki

42
Q

Causative organism of endemic typhus

A

Rick. Typhi— flea born

43
Q

Causative organism of scrub typhus

A

mite born- ricketsiae tsutsugamushi

44
Q

What symptoms does Typhus fever begin with?

A

begins with chills, fever, headache, abrupt onset

45
Q

Symptoms of typhus 5 to 9 days after exposure

A

maculo papular rash in trunk and spreading to limbs

46
Q

Symptoms of severe exposure of typhus

A

meningo encephalitis with delirium and coma

47
Q

Where is epidemic typhus most present?

A

associated with poverty, prevalent in under developed countries

48
Q

Recurrent form of epidemic typhus

A

brill zinssar disease

49
Q

Diagnosis of typhus

A

based on serological tests, immunoflourescent , ELISA

50
Q

Treatment for typhus

A

TC is first choice and chloramphenicol is an alternative choice

51
Q

Prevention of typhus

A

protective clothing, insect repellent, delousing DDT

52
Q

what disease have vaccines available?

A

cox burnetti, rick prowazaki

Microbiology (16 decks)

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