Chapter 13

Question 1

3 diseases caused by Chlamydial infection

Answer 1

Chlamydial urethritis, Lymphogranuloma venereum, Trachoma

Question 2

3 diseases caused by Ricketsial infection

Answer 2

Rochey mountain spotted fever, Q fever, Typhus Fever

Question 3

What kind of parasite is Chlamydiae

Answer 3

obligate intracellular parasites

Question 4

Can Chlamydiae make their own ATP

Answer 4

NO

Question 5

What does Chlamydiae infect?

Answer 5

epithelial cells of skin and mucous membranes

Question 6

Chlamydiae replication cycle

Answer 6

spore like metabolically inert Elementary bodies enter the cell, become metabolically active, reticulate body, undergo repeated binary fission, burst and release daughter elementary body

Question 7

3 types of Chlamydiae

Answer 7

Ch. Psittaci, Ch. Pneumoniae, Ch. Trachomatis

Question 8

How do you get a Ch. Psittaci infection?

Answer 8

bird’s disease- inhalation of dried bird’s feces causes human infection, fever and pneumonia

Question 9

How do you get a Ch. Pneumoniae infection?

Answer 9

communicable by aerosol- causes a typical pneumonia in humans

Question 10

How do you get a Ch. Trachomatis infection?

Answer 10

only in humans- causes trachoma, genital tract infection, lymphogranuloma venereum

Question 11

What is trachoma?

Answer 11

chronic infection of conjunctival mucous membrane- common in Africa and Asia- transmitted by fomites and fingers

Question 12

Who is trachoma highly contagious in?

Answer 12

children- transmitted by fomites and fingers

Question 13

What does late stage trachoma cause?

Answer 13

scarring of conjunctiva and opacities in cornea resulting in blindness

Question 14

What does Type D-K chlamydiae cause?

Answer 14

STD of infection through birth canal- world wide distribution- occurs in higher socio-economic group

Question 15

What does Chlamydial infection cause in new borns?

Answer 15

acute purulent conjunctivitis

Question 16

What does Chlamydial infection cause in adult males?

Answer 16

urethritis which may progress to epidedymitis, proctitis or prostitis

Question 17

What does Chlamydial infection cause in adult women?

Answer 17

causes cervicitis (inflammation of cervix) may progress to salphingitis @ PID often sterility/ectopic gestation

Question 18

What syndrome may patients with genital tract infection develop?

Answer 18

Reiter’s Syndrome

Question 19

What does Ch. Trachomatis L group cause?

Answer 19

lymphogranuloma venereum (LGV)

Question 20

What does LGV cause?

Answer 20

painful ulcers on genitals with inguinal node enlargement, no immunity

Question 21

Lab diagnosis of chlamydial infection?

Answer 21

cause characteristic inclusion bodies in cells- Giemsa stain is used to stain urethral/conjunctival smears to demonstrate infection

Question 22

Tests for lab diagnosis of chlamydial infection?

Answer 22

immunolflourescent test, DNA probe, ELISA

Question 23

What treatment are all chlamydial infections susceptible to?

Answer 23

TC/ Doxy

Question 24

Treatment of chlamydial infection STDS

Answer 24

Azithromycin

Question 25

Treatment of Chlamydial ophthalmia neonatorum

Answer 25

Erythromycin

Question 26

Prevention for Chamydia

Answer 26

no vaccination, erythromycin drops for new borns

Question 27

Define Reiter's syndrome

Answer 27

an autoimmune condition that develops in response to an infection in a part of the body

Question 28

Symptoms of Reiter's Syndrome

Answer 28

an inflammatory arthritis of large joints, inflammation of the eyes, urethritis

Question 29

How is reactive arthritis (reiters syndrome) transmitted?

Answer 29

transmitted through sexual transmitted diseases

Question 30

Define Ricketsiae

Answer 30

obligate intracellular organisms, lack co enzyme A, NAD, ATP

Question 31

How is Ricketsiae transmitted?

Answer 31

arthropod bite

Question 32

Q fever is caused by what organism?

Answer 32

Coxiella burnetti

Question 33

What animals is Q fever present in?

Answer 33

cattle, sheep, goat- but they do not suffer from disease

Question 34

What is Q fever spread by?

Answer 34

animals, amniotic fluid, placenta, urine and feces, aerosol- inhalation even miles from product

Question 35

symptoms of Q fever?

Answer 35

flu like symptoms, pneumonia, hepatitis - acute infection, no rash

Question 36

What is rocky mountain spotted fever caused by?

Answer 36

ricketti- spread by dog tick

Question 37

Symptoms of rocky mountain spotted fever?

Answer 37

flu like symptoms, papulo macular rash, hemorrhages on hand and feet then to trunk, --head ache, delirium, coma in severe cases

Question 38

What is the reservoir and vector of rocky mountain fever?

Answer 38

ticks-- humans are accidental host-- common in children in the spring and early summer

Question 39

3 types of typhus fever

Answer 39

epidemic typhus, endemic typhus, scrub typhus

Question 40

What is epidemic typhus spread by?

Answer 40

human louse

Question 41

Causative organism of epidemic typhus

Answer 41

Ricketsiae Prowazaki

Question 42

Causative organism of endemic typhus

Answer 42

Rick. Typhi--- flea born

Question 43

Causative organism of scrub typhus

Answer 43

mite born- ricketsiae tsutsugamushi

Question 44

What symptoms does Typhus fever begin with?

Answer 44

begins with chills, fever, headache, abrupt onset

Question 45

Symptoms of typhus 5 to 9 days after exposure

Answer 45

maculo papular rash in trunk and spreading to limbs

Question 46

Symptoms of severe exposure of typhus

Answer 46

meningo encephalitis with delirium and coma

Question 47

Where is epidemic typhus most present?

Answer 47

associated with poverty, prevalent in under developed countries

Question 48

Recurrent form of epidemic typhus

Answer 48

brill zinssar disease

Question 49

Diagnosis of typhus

Answer 49

based on serological tests, immunoflourescent , ELISA

Question 50

Treatment for typhus

Answer 50

TC is first choice and chloramphenicol is an alternative choice

Question 51

Prevention of typhus

Answer 51

protective clothing, insect repellent, delousing DDT

Question 52

what disease have vaccines available?

Answer 52

cox burnetti, rick prowazaki