Chapter 13 Flashcards

(52 cards)

1
Q

3 diseases caused by Chlamydial infection

A

Chlamydial urethritis, Lymphogranuloma venereum, Trachoma

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2
Q

3 diseases caused by Ricketsial infection

A

Rochey mountain spotted fever, Q fever, Typhus Fever

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3
Q

What kind of parasite is Chlamydiae

A

obligate intracellular parasites

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4
Q

Can Chlamydiae make their own ATP

A

NO

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5
Q

What does Chlamydiae infect?

A

epithelial cells of skin and mucous membranes

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6
Q

Chlamydiae replication cycle

A

spore like metabolically inert Elementary bodies enter the cell, become metabolically active, reticulate body, undergo repeated binary fission, burst and release daughter elementary body

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7
Q

3 types of Chlamydiae

A

Ch. Psittaci, Ch. Pneumoniae, Ch. Trachomatis

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8
Q

How do you get a Ch. Psittaci infection?

A

bird’s disease- inhalation of dried bird’s feces causes human infection, fever and pneumonia

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9
Q

How do you get a Ch. Pneumoniae infection?

A

communicable by aerosol- causes a typical pneumonia in humans

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10
Q

How do you get a Ch. Trachomatis infection?

A

only in humans- causes trachoma, genital tract infection, lymphogranuloma venereum

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11
Q

What is trachoma?

A

chronic infection of conjunctival mucous membrane- common in Africa and Asia- transmitted by fomites and fingers

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12
Q

Who is trachoma highly contagious in?

A

children- transmitted by fomites and fingers

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13
Q

What does late stage trachoma cause?

A

scarring of conjunctiva and opacities in cornea resulting in blindness

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14
Q

What does Type D-K chlamydiae cause?

A

STD of infection through birth canal- world wide distribution- occurs in higher socio-economic group

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15
Q

What does Chlamydial infection cause in new borns?

A

acute purulent conjunctivitis

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16
Q

What does Chlamydial infection cause in adult males?

A

urethritis which may progress to epidedymitis, proctitis or prostitis

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17
Q

What does Chlamydial infection cause in adult women?

A

causes cervicitis (inflammation of cervix) may progress to salphingitis @ PID often sterility/ectopic gestation

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18
Q

What syndrome may patients with genital tract infection develop?

A

Reiter’s Syndrome

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19
Q

What does Ch. Trachomatis L group cause?

A

lymphogranuloma venereum (LGV)

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20
Q

What does LGV cause?

A

painful ulcers on genitals with inguinal node enlargement, no immunity

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21
Q

Lab diagnosis of chlamydial infection?

A

cause characteristic inclusion bodies in cells- Giemsa stain is used to stain urethral/conjunctival smears to demonstrate infection

22
Q

Tests for lab diagnosis of chlamydial infection?

A

immunolflourescent test, DNA probe, ELISA

23
Q

What treatment are all chlamydial infections susceptible to?

24
Q

Treatment of chlamydial infection STDS

25
Treatment of Chlamydial ophthalmia neonatorum
Erythromycin
26
Prevention for Chamydia
no vaccination, erythromycin drops for new borns
27
Define Reiter's syndrome
an autoimmune condition that develops in response to an infection in a part of the body
28
Symptoms of Reiter's Syndrome
an inflammatory arthritis of large joints, inflammation of the eyes, urethritis
29
How is reactive arthritis (reiters syndrome) transmitted?
transmitted through sexual transmitted diseases
30
Define Ricketsiae
obligate intracellular organisms, lack co enzyme A, NAD, ATP
31
How is Ricketsiae transmitted?
arthropod bite
32
Q fever is caused by what organism?
Coxiella burnetti
33
What animals is Q fever present in?
cattle, sheep, goat- but they do not suffer from disease
34
What is Q fever spread by?
animals, amniotic fluid, placenta, urine and feces, aerosol- inhalation even miles from product
35
symptoms of Q fever?
flu like symptoms, pneumonia, hepatitis - acute infection, no rash
36
What is rocky mountain spotted fever caused by?
ricketti- spread by dog tick
37
Symptoms of rocky mountain spotted fever?
flu like symptoms, papulo macular rash, hemorrhages on hand and feet then to trunk, --head ache, delirium, coma in severe cases
38
What is the reservoir and vector of rocky mountain fever?
ticks-- humans are accidental host-- common in children in the spring and early summer
39
3 types of typhus fever
epidemic typhus, endemic typhus, scrub typhus
40
What is epidemic typhus spread by?
human louse
41
Causative organism of epidemic typhus
Ricketsiae Prowazaki
42
Causative organism of endemic typhus
Rick. Typhi--- flea born
43
Causative organism of scrub typhus
mite born- ricketsiae tsutsugamushi
44
What symptoms does Typhus fever begin with?
begins with chills, fever, headache, abrupt onset
45
Symptoms of typhus 5 to 9 days after exposure
maculo papular rash in trunk and spreading to limbs
46
Symptoms of severe exposure of typhus
meningo encephalitis with delirium and coma
47
Where is epidemic typhus most present?
associated with poverty, prevalent in under developed countries
48
Recurrent form of epidemic typhus
brill zinssar disease
49
Diagnosis of typhus
based on serological tests, immunoflourescent , ELISA
50
Treatment for typhus
TC is first choice and chloramphenicol is an alternative choice
51
Prevention of typhus
protective clothing, insect repellent, delousing DDT
52
what disease have vaccines available?
cox burnetti, rick prowazaki