Chapter 1 Brief History Flashcards
Leeuwenhoek
- dutch scientist
- made/used simple microscopes
- discovered “animalcules” aka microorganisms
Carolus Linnaeus
- developed TAXONOMIC SYSTEM
- grouped similar organisms by similar characteristics
- created 6 categories
6 Categories for Microorganisms
1 Bacteria [Pro] 2 Archea [Pro] 3 Fungi [Euk] 4 Protazoa [Euk] 5 Algae + Plants [Euk] 6 Small multicellular animals [Euk]
Prokaryotes
“pro” - primitive; “karyote” - nucleus
- unicellular; lacks a nuclei and most organelles
- much smaller than eukaryotes
- found wherever there’s enough moisture
- reproduce asexually (binary fission)
Eukaryote
“euk” - true; “karyote” - nucleus
- have nucleus w nuclear membrane
- internal membrane-bound organelles
- larger than prokaryotes
- sexual + nonsex reproduction
2 types of Prokaryotes
1 Bacteria (cell walls w/PEPTIDOGLYCAN) 2 Archaea (no peptidoglycan; other POLYMERS)
how do prokaryotes reproduce?
asexually; binary fission
Archaea
- type of prokaryote
- cells walls contain polymers but NOT peptidoglycan
- lives in very harsh environments
- don’t infect humans
4 types of Eukaryotes
1 Fungi
2 Protazoa
3 Algae + plants
4 small multicellular animals
2 types of Fungi
Molds + Yeast
Fungi
- has membrane bound nucleus
- obtain food fr other organisms
- possess cell walls
Molds
- fungi
- multicellular
- filamentous (grows really long; hairy)
- sexual/asexual spores for reproduction
Yeasts
- fungi
- unicellular
- budding/sexual spores for reproduction
Protozoa
- eukaryote
- unicellular
- lives in water/sometimes animals
- mostly asexual reproduction
- mostly capable of locomotion by pseudopodia, cilia, flagella
Protozoa Locomotion
pseudopodia
cilia
flagella
Algae
- eukaryotes
- unicellular or multicellular
- photosynthetic aka AUTOTROPHS
- simple reproductive structures
Autotroph
-organism that can synthesize its own food/ATP by utilizing soil or sun
Parasitic Worms
-multicellular eukaryotes
-
Virus
- not an organism/cell
- infectious agent
- can only survive in other cells
2 types of Virus
Naked Virus - surrounded by protective protein coat [CAPSID]
Enveloped Virus - contains an additional membrane surrounding the capsid
Bacteriophage
- type of virus that infects bacteria
- virus injects their RNA into bacterial cell
- virus uses bacteria’s organelles to replicate itself
Fermentation
bacteria > acid
yeasts > alcohol
Pasteur
germ theory of disease
Robert Koch
- causative agents of disease
- studied anthrax
Koch’s Postulates
1 causative agent must be found in every case of the disease and absent in healthy hosts
2 agent must be isolated and grown in pure culture
3 disease must be reproduced when a pure culture of the agent is introduced to a healthy/susceptible host
3 agent must be recoverable from the experimental host
Hans Christian Gram
- gram staining technique
- selective + differential stain (allows us to distinguish bw two groups of bacteria based on their cell wall
Semmelweis
- hand-washing
- decreased incidence of puerperal fever
Lister
antiseptic technique in surgery
Nightingale
nursing
Microbial Genetics
study how microbes become more virulent
-transfer virulent genes
Molecular Biology
learning how microbes operate and how their cells function
Recombinant DNA technology
- manipulates genes in microbes for practical applications
- synthesis of insulin using E.Coli
Gene Therapy
inserting missing gene or repairing defective ones in humans
Bioremediation
- using living bacteria, fungi, and algae to detoxify polluted environments
- recycles carbon, nitrogen, and sulfur
Serology
- studying of blood serum
- analyze components and chemicals that fight infection
Serum vs Plasma
serum doesn’t contain fibrinogen; plasma does
Immunology
study of body’s defense against pathogens
Chemotherapy
- chem put into body to fight microbes
- Flemings discovered penicillin
- Domagk discovered sulfa drugs
Defense against disease
1 serology
2 immunology
3 chemotherapy
3 Domains of Microorganisms
1 Bacteria
2 Archaea
3 Eukaryotes
Binary Fission
non-sexual reproduction
Chemotrophs
organisms that obtain energy by the oxidation of electron donors in their environments.
ex) sulfur-oxidizing bacteria
Heterotrophs
an organism deriving its nutritional requirements from complex organic substances.