Ch 49 disorders of anterior pituitary Flashcards

1
Q

condition characterized by overproduction of GH from a tumor. can cause gigantism in children. can lead to hyperglycemia and vision changes

A

acromegaly

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2
Q

treatment options acromegaly (3)

A
  • hypophysectomy
  • radiation
  • drug: octreotide
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3
Q

why is hyperglycemia common with acromegaly

A

growth hormone blocks action of insulin, causing glucose intolerance and S+S of diabetes

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4
Q

assessment findings acromegaly (6)

A
  • change in ring size, hat size
  • joint pain
  • change in facial features
  • organomegaly
  • hypertension
  • deepening of voice
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5
Q

treatment of choice for acromegaly

A

hypophysectomy

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6
Q

important nursing considerations for pts after hypophysectomy surgery (4)

A
  • avoid vigorous coughing, sneezing and blowing nose
  • avoid bending over
  • avoid use of toothbrushes until incision heals
  • keep hob atleast 30 degrees
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7
Q

what puts pt at higher risk for developing meningitis after hypophysectomy surgery

A

(fluid with glucose >30=) CSF leakage from open connection with brain through nose

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8
Q

what hormones need to be replaced lifelong after hypophysectomy surgery (3)

A
  • ADH
  • cortisol
  • thyroid
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9
Q

2 potential complications after hypophysectomy surgery

A

diabetes insepidus

meningitis

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10
Q

possible causes SIADH (3)

A
  • head injury
  • cancer
  • anesthesia
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11
Q

S+S SIADH (7)

A
  • less urine output (INCREASED URINE OSMOLALITY)
  • dilutional hyponatremia
  • muscle cramps
  • pain
  • weakness
  • weight gain
  • DECREASED BLOOD OSMOLALITY
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12
Q

treatment mild SIADH (3)

A
  • restrict fluid (800-1000 mL/day)
  • maybe give furosemide
  • maybe give demeclocycline
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13
Q

treatment severe SIADH (2)

A
  • hypertonic IV solution (3%NaCl) at SLOW infusion rate

- restrict fluid (500 mL/day)

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14
Q

treatment chronic SIADH (3)

A
  • give lithium
  • hob <10 degrees
  • restrict fluid (800-1000 mL/day)
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15
Q

is there too much or too little ADH made in SIADH

A

too much

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16
Q

how might demeclocycline help with mild SIADH

A

blocks affect of ADH on renal tubules and results in more dilute urine

17
Q

how might lithium help with chronic SIADH

A

blocks hormone production

18
Q

is there too much or too little ADH made in diabetes insipidus

A

too little

19
Q

how does DI effect urine osmolality and blood osmolality

A

decreases urine osmolality (100-600)

increases blood osmolality

20
Q

how does SIADH effect urine osmolality and blood osmolality

A

increases urine osmolality

decreases blood osmolality

21
Q

three types DI

A
  • nephrogenic (problem with kidneys)
  • central (not enough ADH)
  • primary (excess water intake)
22
Q

S+S DI (3)

A
  • hypernatremia
  • polydipsia
  • nocturia
23
Q

treatment central DI (3)

A
  • D5W titrated to replace urine output
  • DDAVP (or vasopressin - synthetic ADH)
  • chlorpropamide (decreases thirst)
24
Q

hormone replacement of choice for central DI

A

DDAVP

25
Q

routes of admin for DDAVP (4)

A
  • po
  • IV
  • subq
  • nasal spray
26
Q

treatment nephrogenic DI (3)

A
  • low sodium diet
  • thiazide diuretics
  • indomethacin (NSAID increases renal responsiveness to ADH)
27
Q

possible causes hypopituitarism (3)

A
  • tumor
  • stroke
  • autoimmune
28
Q

condition caused by severe postpartum hemorrhaging that can result in hypopituitarism

A

sheehan syndrome

29
Q

very rare total failure of pituitary gland resulting in deficiency in all pituitary hormones

A

panhypopituitarism

30
Q

treatment hypopituitarism (2)

A
  • replace hormones (somatropin)

- surgery/radiation

31
Q

various manifestations of hypopituitarism (4)

A
  • dry and pale skin
  • fatigue
  • decreased facial hair, muscle mass, libido
  • cold intolerance