ch 33 coronary artery disease and acute coronary syndrome Flashcards
nonmodifiable risk factors for CAD (4)
- increasing age
- gender (most = middle aged men)
- ethnicity (white)
- genetic predisposition and family history
modifiable risk factors for CAD (9)
- increased serum lipids (diet and exercise)
- smoking
- obesity
- metabolic syndrome
- HTN
- physical immobility
- diabetes
- psychologic states
- hemocysteine level
examples of beginning injuries that cause atherosclerosis (3)
- HTN
- T2 DM
- smoking
recommended HDL levels for male and female
M >40
F>50
HDL levels that indicate low risk CAD
> 60
HDL levels that indicate high risk CAD
<40
recommended LDL levels
<100
LDL levels that indicate moderate risk CAD
130-159
LDL levels that indicate high risk CAD
> 160
first line meds for high cholesterol
antihyperlipidemics (statins)
purpose of statins (2)
lowers cholesterol
lowers risk MI and stroke
what should you monitor in pts on statins
liver enzymes (creatinine)
common side effects of statins
muscle soreness/aches
complication of statins
rhabdomylosis: breakdown of skeletal muscle, leads to renal failure
med: cholesterol absorption inhibitor
inhibits absorption cholesterol in GI
side effect: diarrhea
ezetimibe
side effect of niacin and how to prevent it
severe facial flushing after taking
-prevent: take 81 mg aspirin 30 mins before
med that reduces triglyceride levels (fibrates)
fenofibrate
med that inhibits absorption cholesterol in intestines (bile acid sequestrant). usually given to prevent diarrhea after cholecystectomy
cholestyramine
2 alternative therapies for treating high LDLs
high doses garlic
red yeast rice
what should you watch for with pt taking high doses garlic supplements
increased bleeding time
lack of bloodflow to area of heart, demand O2>supply
ischemia
what diseases are associated with silent ischemia (2)
- HTN
- T2 DM