Ch 18 (test 4) Flashcards
Sympathetic nervous system is part of the
autonomic nervous system
counter-part of SNS is
parasympathetic nervous system
Receptor sites for catecholamines are
adrenergic receptors
adrenergic receptors are divided into
alpha receptors: cause vasoconstriction (-GI)
beta receptors: inhibitory/cause dilation (except stimulation of cardiac contractions)
Beta receptors types
Beta 1: produce cardiac stimulation
Beta 2: cause bronchodilation.
responses to catecholamine binding to receptor sites.
- smooth muscle constriction
- heart rate increase
- blood vessel constriction
MAO and COMT
enzymes that stop the action of catecholamines.
Sympathetic nervous system is responsible for
fight or flight response
Parasympathetic nervous system responsible for
rest and digest response
Receptor sites for acetylcholine
nicotinic and muscarinic receptors
acetylcholine is inactivated by
acetylcholinesterase
andrenergic drugs/sympathomimetic drugs
stimulate the sympathetic nervous system and its functions.
mimic norepinephrine, epinephrine and dopamine. Bathe synapse to produce a neurological response.
Therapeutic uses for adrenergic drugs
- Asthma/Bronchodilator
- Glaucoma/decreases IOP
- Heart failure/support
- hypotension/vasopressor(vasoactive drug)
Proventil (albuterol)
Brochodilator
inhalation, oral, injection
Adrenalin (epinephrine)
bronchodilator
anaphylaxis treatment