Ch 12 Nervous System - Neurophysiology Flashcards

1
Q

what happens when neurotransmitters are released so we get different outcomes?

A

synaptic transmission

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2
Q

what makes electricity flow in the axon?

A

actions potentials

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3
Q

how do dendrites governs whether an axon will fire?

A

integration of signals

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4
Q

excitable/input

A

graded action potentials convert into action potentials
few voltage gated Na+ and K+ channels
many ligand gated mechano gated channels (depending on location)

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5
Q

conductive

A

action potentials
only Na+ and K+ voltage gated channels

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6
Q

transmissive

A

Ca++ voltage gated channels
vesicles containing neurotransmitter
release of neurotransmitter

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7
Q

polarization

A

charge differential

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8
Q

is there a higher charge inside or outside cell

A

outside cell

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9
Q

what is resting membrane potential

A

-70mV

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10
Q

hyperpolarization

A

more + ions leaking out than coming back in

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11
Q

depolarization

A

more + ions leaking in than coming back out

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12
Q

how does a neuron regulate its charge?

A

K+ and Na+ voltage gated channels and K+ and Na+ leak channels

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13
Q

explain one action potential

A

Na+ begins to move into neuron and raises the charge to -55mV. at this threshold, voltage gated Na+ channels open, and Na+ rushes into the cell. the charge is raised to +30mV, and channels close. at this point, the voltage gated K+ channels open, and K+ rushes out of the neuron, lowering the charge. at -70mV, these channels close, but slowly, so the charge lowers to -90, the channels finishing closing, and neuron returns to normal charge through leak channels.

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14
Q

explain graded potentials

A

ligand binds to a ligand gated K+ channel. this causes the channel to open, and K+ to move out of the cell, lowering the charge. the ligand quickly falls off, and the channel closes. the cell returns back to -70mV due to the K+/Na+ pump. called inhibitory
for Na+, same process except Na+ pours into cell and raises the charge closer to the threshold. this is called excitatory

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15
Q

electrical synapses

A

less common than chemical synapses
correspond to gap junctions found in other cells types
important in CNS for arousal from sleep, mental attention, emotions and memory, and ion and H2O homeostasis

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16
Q

chemical synapses

A

specialized for the release and reception of neurotransmitters
composed of axon terminal of the presynaptic neuron, which contains synaptic vessels, and reception region on dendrite(s) or soma of the postsynaptic neuron

17
Q

chemical synapse process

A

when +30mV is reached at the synapse, it will open Ca++ voltage gated channels. this causes the vesicles to move to surface of cell and release neurotransmitters

18
Q

cleaning up neurotransmitters

A

reuptake (resorbed by astrocytes or presynaptic terminals)
enzymatic breakdown
diffusion (slowest)