Ch 12 Nervous System - Neurophysiology Flashcards
what happens when neurotransmitters are released so we get different outcomes?
synaptic transmission
what makes electricity flow in the axon?
actions potentials
how do dendrites governs whether an axon will fire?
integration of signals
excitable/input
graded action potentials convert into action potentials
few voltage gated Na+ and K+ channels
many ligand gated mechano gated channels (depending on location)
conductive
action potentials
only Na+ and K+ voltage gated channels
transmissive
Ca++ voltage gated channels
vesicles containing neurotransmitter
release of neurotransmitter
polarization
charge differential
is there a higher charge inside or outside cell
outside cell
what is resting membrane potential
-70mV
hyperpolarization
more + ions leaking out than coming back in
depolarization
more + ions leaking in than coming back out
how does a neuron regulate its charge?
K+ and Na+ voltage gated channels and K+ and Na+ leak channels
explain one action potential
Na+ begins to move into neuron and raises the charge to -55mV. at this threshold, voltage gated Na+ channels open, and Na+ rushes into the cell. the charge is raised to +30mV, and channels close. at this point, the voltage gated K+ channels open, and K+ rushes out of the neuron, lowering the charge. at -70mV, these channels close, but slowly, so the charge lowers to -90, the channels finishing closing, and neuron returns to normal charge through leak channels.
explain graded potentials
ligand binds to a ligand gated K+ channel. this causes the channel to open, and K+ to move out of the cell, lowering the charge. the ligand quickly falls off, and the channel closes. the cell returns back to -70mV due to the K+/Na+ pump. called inhibitory
for Na+, same process except Na+ pours into cell and raises the charge closer to the threshold. this is called excitatory
electrical synapses
less common than chemical synapses
correspond to gap junctions found in other cells types
important in CNS for arousal from sleep, mental attention, emotions and memory, and ion and H2O homeostasis