Cardiovascular disease Flashcards
What are cardiovascular diseases
Disorders of coagulation and also problems caused to other organs due to issues with blood supply
Main types of cardiovascular diseases
- Coronary heart disease - Angina (Not enough oxygen), Myocardial infraction (death of muscle)
- Stroke and transient ischemic attack
- Peripheral arterial disease
- Aortic disease
Epidemology of CVD
- 7 mil people living with it
- Cause 1/4 of deaths and premature
Diabetes
- Blood sugar levels are elevated for a prolonged period of time causing damage to inner lining of blood vessel
- Risk factor for CVD
High cholesterol
- High levels of LDL is associated in risk factor for CVD
- Lower target cholesterol levels
Air pollution
- Risk factor significantly impacting circulatory health
Smoking
- 1 in 8 adults smoke cigarettes
- Risk factor to CVD
Overweight and obesity
- 1 in 6 heart and circulatory disease deaths related to BMI
PRIMARY prevention
- Alter modifiable risks
to reduce incidence in disease-free individuals or in the population. - Discuss lifestyle repeat check ups
SECONDARY prevention
strategies target individuals with established disease has an ‘event’, to reduce morbidity and mortality
Non-acquired CVD
- Due to lifestyle can be preventable
- Influenced by non-modifiable risk factor
Risk Stratification
- Early intervention for patients over the age of 40 record in medical notes
Hypertension with type 2 diabetes OR without type 2 and not African (<55)
Step 1 - ACEi/ARB
Step 2 - + CCB/Thiazide -like diuretic
Step 3 - both Thiazide and Calcium CB
Hypertension and type 2 >55 and African
Step 1 - CCB
Step 2 - + ACEi/ARB or Thiazide -like diuretic
Step 3 - both Thiazide and CCB
Q-risk
- 10% chance carry out treatment effect in the next 10 yrs
Hyperlipidemia with risk assessment
- Assess using Q-risk for the next 10 yrs
With type 2 higher dose
Hyperlipidemia without risk assessment
- Primary prevention for those with type 1 diabetes
Secondary prevention CHD
- Coronary arteries become narrowed build of atheroma
- Pain and angina
- CHD and MI twice likely for stroke
Acute Coronary Syndrome
- Rupture/erosion of an
atherosclerotic plaque and subsequent thrombus formation
Thrombus PRIMARY treatment
- Primarily due to platelet aggregation under high stress
- Immediate treatment will often involve PCI or CABG
Secondary treatment thrombus
antiplatelet therapy – aspirin, clopidogrel, ticagrelor,
prasugrel
ISCHAEMIC STROKE
- A blockage where a small blood clot lodges in a vessel narrowed by an atheroma
- Blocks oxygenation of the affected part of the brain
PERIPHERAL ARTERY
DISEASE
- Build up of fatty deposits restrict blood supply to legs
- Tiredness of legs due to restricted blood flow
- second p
rev antiplatelets aspirin
ARRYTHMIAS
- Control heart rate and rhythm to prevent arrest
- Prophylactic medication required to prevent stroke as primary prevention
- Incomplete ventricular
emptying leads to clot formation, which can travel to the brain and cause a stroke