Cardiorespiratory responses to exercise (Year 2) Flashcards

1
Q

Respiratory Volume Parameters:

A
  • Tidal Volume(TV)-Volume inspired or expired per breath
  • Inspiratory Reserve Volume(IRV)-Maximum inspiration at end of TV
  • Expiratory Reserve Volume (ERV)-Maximum expiration at end of TV
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Ventilation during Exercise:

A
  • Resting minute ventilation:5 –6 l/min
  • Maximal minute ventilation:>100l/min
  • Linear increase at submaximal intensities

•Breathing capacity does not reach maximal regardless
of exercise intensity

•Not the factor limiting O2 delivery during exercise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Cause of hypoxemia in Athletes

A
  • IncreasedO2extraction→decreasedPO2invenous blood
  • Increased cardiac output→decreased transit time
  • CombinedeffectismoreO2needs to be taken up in less time
  • If this isn’t achieved→hypoxemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Adaptions to endurance training?

A
  • Little effect on lung structure or function at rest
  • Decreased submaximal ventilation
  • Increased pulmonary ventilation during maximal exercise:
  • Increased respiratory rate
  • Increased tidal volume
  • Increased pulmonary diffusion:
  • Increased ventilation
  • Increased perfusion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Respiratory Muscle Fatigue and exercise tolerance?

A
  • Study explored the effects of increasing and decreasing inspiratory muscle work on quadriceps muscle fatigue
  • Percent change in twitch force: the reduction in the average quadriceps force output
  • Equal cycle ergometer work rates and durations
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Respiratory Muscle Training:

A
  • Utilises restricted airflow breathing exercise to increase the mechanical load on the respiratory muscles
  • Provides a stimulus to elicit a hypertrophic response
  • Resistive training -muscles subjected to an external load
  • Inspiratory flow resistive loading
  • Inspiratory threshold loading
  • Expiratory threshold
  • Endurance training-high target levels of ventilation for up to 30 minutes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Heart rate Variability?

A

• Analysis of variability in consecutive RR
intervals

  • Insight into autonomic nervous system control
  • Central to physiological coordination
  • High variability is healthy
  • Sensitive to numerous factors
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Factors affecting heart rate variability: Non-Influenceable Physiological parameters

A

Age, gender, circadian rhythm, genetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Factors affecting heart rate variability: Diseases

A

Sepsis, heart disease, lung diseases,
renal diseases, psychiatric diseases,
metabolic diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Factors affecting heart rate variability: Influenceable Lifestyle Factors

A

Physical fitness, sporting activity, increased

body weight, smoking, alcohol abuse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Factors affecting heart rate variability: External Factors

A

Noise, night shift work, harmful

substances, medications

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Heart rate variability and posture: standing up?

A

decrease venous return–>

decrease end-diastolic volume–>

decrease stroke volume–>

decrease cardiac output–>

decrease blood pressure–>

baroreceptors–sensory neurons–>

Medulla oblongata increases sympathetic input and decrease parasympathetic input–>

increase in cardiac rate and vasoconstriction of arterioles–>

increase in peripheral resistance and cardiac output–>

increase blood pressure (negative feedback response)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Cardiovascular hemodynamics?

A

Cardiac output= stroke volume x heart rate

CO (Q) – volume of blood pumped by one ventricle in a given period
- Typically ~5L∙min-1

SV – volume of blood pumped by one ventricle in one contraction
- Typically ~70mL at rest

HR – rate of contraction of the heart
- Typically ~70-75 bpm but innate HR is 90-100 bpm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Effect of pH, CO2 and O2 on the CV system?

A
  • Effect of each related through detection by chemoreceptors and by relationship with respiratory system
  • Two sets of chemoreceptors

• Peripheral – sensitive to pH, CO2
, O2

• Central – sensitive CO2

• Increases in CO2
concentration decrease pH because CO2
is mainly
transported as carbonic acid

  • Parasympathetic withdrawal and sympathetic stimulation
  • Increased HR contractility -> increased Q

• Greater blood flow through the lungs so CO2
is expired

• Negative feedback loop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Stroke volume

A

Stroke Volume (SV) = EDV – ESV

  • Frank Starling Mechanism
  • EDV increases with venous return
  • ESV decreases due to stretch
  • Increase in SV with exercise intensity until:
  • 40-60% VO2max (Wilmore and Costill, 1994)
  • Or 120-140 bpm (McArdle et al, 1995)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Heart rate?

A
  • Submaximal work rates
  • Linear increase proportional to oxygen consumption
  • Conconi deflection

• Point at which HR tends to increase at a reduced
rate

17
Q

Blood Composition Changes During Exercise: Blood pH

A
  • Lowered due to dissociation of lactate and transport of CO2
  • Arterial blood: rest ~7.4 to exercise ~7.1 (Cheetham et al., 1986)
18
Q

Blood Composition Changes During Exercise: Oxygen Content

A
  • Increased arteriovenous oxygen difference
  • Decreased venous oxygen content
  • Oxyhaemoglobin dissociation curve shifts right
19
Q

Blood Composition Changes During Exercise: Plasma Volume

A
  • Exercise decreases blood plasma volume and increases haematocrit
  • Initially due to an increase in blood pressure and osmatic pressure
  • Later, increased by sweating
20
Q

Influence of Training on Hemodynamics

A
  • Training is a potent stimulus to the cardiovascular system
  • Endurance training is associated with:
  • Increased SV at rest and peak
  • Decreased resting, unchanged peak HR
  • Increased Q at peak – rest?
  • Influence of resistance training less clear but likely similar

• Influence of training in children controversial but likely similar on a
smaller magnitude

21
Q

Mechanistic Basis for Increased Peak VO2: Morphological

A
  • Increased left ventricular dimension and mass
  • Increased intraventricular wall thickness?
  • Increased posterior wall thickness?

Peak VO2 = cardiac output (Q) * arterio-venous O2 difference (a-vO2 diff)= stroke volume (SV) * heart rate (HR)

22
Q

Mechanistic Basis for Increased Peak VO2: Functional

A

• Altered SV response pattern

• No influence of training status at rest or
maximal exercise

• Right shifted response pattern

Peak VO2 = cardiac output (Q) * arterio-venous O2 difference (a-vO2 diff)
Balance between O2 delivery and O2 utilisation; can be assessed using NIRS

23
Q

Athlete’s heart: Characterised by?

A
  • Characterised by:
  • Bradycardia
  • Cardiac hypertrophy
  • Cardiomegaly
24
Q

Athlete’s heart: Hypertrophic cardiomyopathy is characterised by:

A
  • Thickening of heart’s walls
  • Similar ECG pattern
  • 1 in 500 – leading cause of sudden cardiac death in young athletes