Acid/Base Balance Flashcards

1
Q

strenuous exercise does not produces lactic acid, what does it actually produce?

A

it produces lactate

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2
Q

lactate does not what?

A

cause a decrease in pH

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3
Q

what are the parts of atom?

A

proton +
Neutron
Electron -
and the orbital

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4
Q

what does Hydrogen does NOT occur as:

A

–H (hydrogen atom)

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5
Q

what does Hydrogen occurs as:

A

–H2 (hydrogen gas)

–H+ (hydrogen ion / proton)

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6
Q

Acids:

A

–Molecules able to donate a hydrogen ion (H+)

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7
Q

Bases:

A

–Molecules able to accept a H+

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8
Q

Strong acids (like HCl):

A

–dissociate completely
•All protons are released into solution

–HCl = H+ + Cl-

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9
Q

Weak acids (like lactic acid):

A

–dissociate partly
•Some of the protons are released into solution

–lactic acid=H+ + lactate-

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10
Q

The more the H+ is in the solution, the more what?

A

The more H+ is in solution, the more acidic the solution

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11
Q

The concentration of H+ is presented as pH:

A

pH = -log[H+]

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12
Q

The concentration of H+ in pure water is:

A
  • 0.0000001 mol·L-1
  • 10-7 mol·L-1
  • -log[10-7 ] = 7
  • This is called ‘neutral’
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13
Q

Pure water has a neutral pH:

A

10-7 mol·L-1 or pH = 7

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14
Q

Acidic solutions have a lower pH:

A

[H+] > 10-7 mol·L-1 or pH < 7

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15
Q

Alkaline solutions have a higher pH:

A

[H+] < 10-7 mol·L-1 or pH > 7

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16
Q

The scale is logarithmic:

A

pH = 6 has ten times more H+ than pH = 7

17
Q

what is the resting blood muscle and cytoplasm pH?

A
  1. 4 (blood)
  2. 2 (muscle)
  3. 8 (cytoplasm)
18
Q

what is the stomach pH?

A

1.2

19
Q

why is it crucial to regulate pH?

A

Enzymes require a narrow pH range to function

20
Q

Buffers limit changes in [H+] and thus pH

Required in the body to regulate pH

A

–To ensure optimal functioning of enzymes

21
Q

what are buffers?

A

Buffers are weak acids

22
Q

If [H+] increases, some of it will bind to B-

A

–Therefore, it limits the drop in pH!
–If you increase [BH], [H+] will increase too
–If you increase [B-], [H+] will decrease

23
Q

If an acid / additional protons are added:BufferH Buffer- + H+ + 100 H+, then what?

A

•Then some of these will bind to the buffer
•The increase in protons is reduced
•The drop in pH is reduced:
BufferH

24
Q

If an acid / additional protons are added:H2CO3 HCO3- + H++ 100 H+, then what?

A
  • Then some of these will bind to bicarbonate
  • The increase in protons is reduced
  • The drop in pH is reduced:H2CO3
25
Q

Bicarbonic acid can split into what?

A

water and CO2:H2O + CO2 H2CO3 HCO3- + H+

26
Q

•CO2 can be exhaled, doing what?

A

shifting the balance

Removing CO2 means more bicarbonic acid will be split into water and CO2 and more protons will combine with bicarbonate

27
Q

•If [H+] rises:

A

–The reaction will shift to produce more H2CO3

–H2CO3 dissociates to produce H2O and CO2

–CO2 is expired

28
Q

•If [H+] drops:

A

–The reverse happens: CO2 combines with H2O

–Bicarbonate dissociates to raise [H+]

29
Q

Drop in blood pH with intense exercise:

A

–7.4 to ~7.0

30
Q

Drop in muscle pH with intense exercise:

A

–7.2 to 6.4