cardiac conductive physiology Flashcards

1
Q

What is the rate of the SA node?

A

60-100, starts the impulse here

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2
Q

Which artery supplies the SA note?

A

Right Coronary

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3
Q

What is the cardiac conduction velocity? of the tissue

A

Purkinje fibers> atrial myocytes > ventricular myocytes > AV node

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4
Q

What is the rate of the AV node?

A

45-55

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5
Q

What are the two types of cells in the heart?

A

pacemaker cells and non pacemaker cells

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6
Q

What are the pacemakers cells?

A

SA node/ AV node

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7
Q

Why is there no resting potential in the pacemaker cell

A

because of the Na influx current

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8
Q

Which ions are responsible for depolarization in terms of pacemaker potential?

A

1) permeability of the Na current (slow)
2) permeability of T type (transient) and L type Ca, make it more depolarized

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9
Q

What drives the action potential depolarization in the pacemaker?

A

Calcium (L type)

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10
Q

Pacemaker action potential refers to what heart rate or contractility?

A

heart rate

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11
Q

Non pacemaker cell refers to HR or contractility?

A

contractility

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12
Q

Which cells of the heart do not present with automaticity?

A

non pacemaker cells

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13
Q

do not exihibit automacity, Phases 0-4 present, resting potential phase present- which cells

A

non pacemaker action potential

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14
Q

Which ion is responsible for action potential depolarization (non pacemaker)

A

Fast Na

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15
Q

What is responsible for plateau non pacemaker action potential?

A

Ca (in) and K (efflux)

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16
Q

ventricular systole begins at which part of the action potential

A

phase 2

17
Q

What is the ddx for QT interval prolongation?

A

drugs
A- antiarrhytmics quinidine
B- macrolide (fluoroquinolones)
C- psyChotics- haloperidol
D- antiDEPRESSANTs: TCA
E- antiememtics: ondansetron
F- antifungals: azoles

Romano Ward Syndrome
Jervell and Lange Nielsen Syndrome

18
Q

What is long QT syndrome

A

delayed ventricular depolarization
impair the potassium channels

19
Q

What is Brugada syndrome

A

autosomal dominant condition from sodium channelopathy of non pacemaker cells.

20
Q

What can lead to increased torsades de pointe

A

increased QT interval

20
Q
A