Antiarthymics

Question 1

Antihistone antibodies are associated with what pathology?

Answer 1

drug induced lupus

Question 2

Drug induced lupus- which drugs

Answer 2

INH, hydrazaline, procainamide

Question 3

When do you use class IB antiarrhythmics?

Answer 3

in recent MIs, increased efficacy in ischemic purkinje and ventricular myocardial cells

Question 4

Which class is contraindicated in ischemic heart disease?

Answer 4

class IC, flecainide, propafenone.

Question 5

What is use dependence?

Answer 5

heart rate increases, sodium channels of the spend less time at rest - at higher heart rates this means more time for class IC to bind and block sodium channels and less time to dissociate from sodium channels

Question 6

Which class as the strongest binding and slowest dissociation

Answer 6

Class IC

Question 7

Contraindications to beta blockers

Answer 7

ashtma, cocaine use, hypoglycemia

Question 8

When do you give adenosine?

Answer 8

superventricular tachycardia

Question 9

Which substances attenuate adenosine?

Answer 9

Caffeine, Theophylline