Carbohydrates 1 Flashcards

1
Q

What is stage 1 of catabolism?

A

food –> building blocks

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2
Q

What is stage 2 of catabolism?

A

building blocks–> simpler molecules

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3
Q

What is stage 3 of catabolism?

A

Krebs

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4
Q

What is stage 4 of catabolism?

A

electron transport chain and oxidative phosphorylation

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5
Q

What enzymes breakdown carbohydrates?

A

glycosidase enzymes

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6
Q

What transporter activley absorbs sugars from SI?

A

Na- dependent glucose transporter 1 (SGLT1)

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7
Q

What transporter passively absorbs glucose?

A

GLUT2

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8
Q

How does glucose reach target cells?

A

GLUT 1-5

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9
Q

What is primary lactase deficiency? Who does it effect?

A

absence of lactase persistence allele

ADULTS

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10
Q

What is secondary lactase deficiency?

A

occurs as a result of injury to SI generally reversible

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11
Q

What is the autosomal recessive form of lactose deficiency?

A

congential lactase deficiency

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12
Q

Why can cellulose not be digested by the body?

A

contains beta 1-4 glycosidic bond which the enzymes cannot digest

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13
Q

Why are some tissue glucose dependent? Give examples

A

no mitochondria to carry out pathways other than glycolysis

RBCs, neutrophils

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14
Q

What are the key features of glycolysis?

A

C6 glucose to 2 c3 pyruvate

net production 2 ATP, 2 NADH

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15
Q

What enzyme allows glycolysis to work anaerobically?

A

lactate dehydrogenase

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16
Q

What enzyme is key in the regulation of glycolysis? What step does it catalyse?

A

phosphofructokinase-1

fructose-6-phosphate –> fructose 1,6- bisphosphate

17
Q

What step does hexokinase catalyse?

A

glucose –> glucose-6-phosphate

18
Q

What product does RBC use from 1,3 bisphosphoglycerate and what enzyme catalyses the reaction?

A

2,3 bisphosphoglycerate
allows o2 release from Hb
bisphosphoglycerate mutase