Candidiasis Flashcards
What is candidiasis?
oral infection, resulting from yeasts
What yeast is usually responsible for candidiasis?
yeasts of the genus Candida, mostly C albicans
What sort of infection is candidiasis?
superficial local mucosal infection, capable of focal invasion and dissemination
What are RF for candidiasis?
- HIV infection
- Xerostomia
- use of dentures
- malnutrition
- advanced malignancy
- cancer chemotherapy or radiotherapy
- pregnancy
- recent immunosuppressive
- antibiotic therapy
What is the presentation for thrush?
creamy white or yellowish plaques, fairly adherent to oral mucosa
What is the presentation for angular chelitis?
cracks, ulcers or crusted fissures radiating from angles of the mouth (angular cheilitis)
What investigations are done for candidiasis?
- Clinical diagnosis
2. Superficial smear of lesion for microscopy
What is 1st line treatment for mild candidiasis?
topical antifungal e.g.. clotrimazole ororpharyngeal 10mg
What is the treatment for severe candidiasis?
Systemic antifungal treatment e.g. fluconazole 200mg
What is the 1st line treatment for angular chelitis?
antifungal cream or ointment
Where is candidia albicans?
commensal in mouth, GI tract, and vagina
