Cáncer Flashcards

1
Q

P53 es un supresor que al estar mutado no logra unirse al

A

ADN.

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2
Q

Cuál es el efecto Warburg

A

Células hipoxicas utilizan la glucosa y generan lactato como desecho, el cual será utilizado por células normoxicas como energía.

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3
Q

Apoptosis y autofagia son……1…… y la necrosis ….2….

A

1 Enemigos de la neoplasia
2 Panas de la neoplasia

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4
Q

Bax y Bak

A

Proapoptóticos (malo para el ca)

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5
Q

BCLongi2 y BCLongiX

A

Antiapoptótico.

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6
Q

Inmortalidad replicativa

A

Inhibe telomerasa

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7
Q

Antiinflamatorio selectivo

A

Inflamación promovida por el tumor

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8
Q

Inhibe señalización VEGF

A

Inducción de angiogénesis

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9
Q

Inhibe parp

A

Genera mutación e inestabilidad

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10
Q

Inhibe EGF

A

Proliferación sostenida

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11
Q

Miméticos BH3 proapoptóticos

A

Evade apoptosis

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12
Q

Inhibe HGF

A

Invasión y metástasis

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