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Fisiopatología > Aterotomatosis > Flashcards

Aterotomatosis Flashcards

1
Q

Ros

A

Radical dañino
Descomposicion via catalasa y glutation peroxidasa
Reaccionan con carbohidratos lipidos de membrana
Altera síntesis de proteínas a nivel de ADN (ruptuta)

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2
Q

Ateroesclerosis

A

Acumulacion de grasa en capa intima de vasos
Predisposicion genética

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3
Q

Fase de desarrollo de aterosclerosis

A

Fase lipidica
Progresion de la placa
Rotura de placa aterosclerótica (formación de trombos)

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4
Q

Formacion de placa aterosclerótica

A

Etapa1: acumulacion de lipoproteínas LDL, estres oxidativo
Etapa 5: macrófago incorpora lipido al citoplasma (liberación de citoquinas)
Etapa 7: formacion de celula espumosa (célula de la aterosclerosis) que forma la placa (funcion inflamatoria)

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5
Q

Pricipal lugsr de formacion de placa aterosclerotica

A

Bifurcacion carotidia por flujo turbulento (estimulacion mecánica)

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6
Q

Placa estable y placa vulnerable

A
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7
Q

Factores de riesgo

A

Ser hombre (menos estrógeno)
Aumento de LDL

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8
Q

Glutation es un antioxidante

A

Enzimático

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9
Q

Fuentes enzimáticas

A

xantina oxidasa
NADPH
Nos

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Fisiopatología (17 decks)

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