C5: Nervous System Flashcards
neuron
the functional unit of the nervous system
- synapse
- what are the 2 types of synapse?
- a junction between the axon terminus of a neuron and the dendrites, soma, or axon of a second neuron
- electrical and chemical
- electrical synapse
- what happens to action potential as a result of an electrical synapse?
- occur when the cytoplasms of two cells are joined by gap junctions
- it will spread directly from one cell to the other
- chemical synapse
- what happens to action potential as a result of an chemical synapse?
- found at the ends of axons where they meet their target cell
- it is converted to a chemical signal
what are the 8 steps required in order for a signal to be transmitted across a a chemical synapse?
- an AP reaches the end of an axon (synaptic knob)
- depolarization of the presynaptic membrane opens voltage gated calcium channels
- calcium influx into the presynaptic cell causes exocytosis of neurotransmitter stored in secretory vesicles
- neurotransmitter molecules diffuse across the narrow synaptic cleft
- neurotransmitter binds to receptor proteins in the postsynaptic membrane. these receptors are ligand gated ion channels
- the opening of these ion channels in the post synaptic cell alters the membrane polarization
- if the membrane depolarization of the postsynaptic cell reaches the threshold of voltage gated sodium channels, an AP is initiated
- neurotransmitter in the synaptic cleft is degraded and/or removed to terminate the signal
- what is a common example of a chemical synapse?
- what neurotransmitter is involved here?
- neuromuscular junction (is between neurons and skeletal muscle)
- acetylcholine (ACh) is released
what are 4 other common neurotransmitters (besides ACh)?
- gamma-aminobutyric acid (GABA)
- serotonin
- dopamine
- norepinephrine
excitatory neurotransmitter
- ex?
a neurotransmitter that opens a channel that depolarizes the postsynaptic membrane
- acetylcholine
inhibitory neurotransmitter
a neurotransmitter that induces hyperpolarization of the postsynaptic membrane
synaptic transmission
when an action potential reaches the end of an axon at a synapse, the signal is transformed into a chemical signal with the release of a neurotransmitter into the synaptic cleft
describe a neuron’s structure
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within a neuron,
what do dendrites do?
collect incoming signals
within a neuron,
the cell body/soma contains ____
organelles
within a neuron,
the axon hillock is where ____
summation occurs
summation
decides whether an action potential is fired or not
within a neuron,
a myelin sheath is made of?
schwann cells in the PNS and olgiodendrocytes in the CNS
saltatory conduction
when the myelin sheath speeds up the movement of action potentials by forcing the action potential to jump from node to node
in the sodium potassium ATPase pump,
- what ions are transported?
- active/ voltage-gated regulation?
- active/passive transport?
- function?
- 3 Na+ ions out, 2 K+ ions in
- no regulation, always active
- primary active transport
- maintains resting membrane potential