C3.2 Defense against disease Flashcards
Pathogens
Organisms that cause disease (Bacteria, Fungi, Virus, Prions)
Commensal bacteria
Bacteria residing in the human body that are not harmful
Platelets
Small fragments of blood cells that form clots to stop bleeding
Innate immunity
Rapid non-specific response to pathogens - attempts to prevent entry in the first place (mucous membranes, skin..)
Adaptive immunity
Slower specific response regulated by lymphocytes - stronger and longer lasting
Lymphocytes
White blood cells produced in bone marrow which regulate adaptive immunity
Helper T-Lymphocytes
Recognizes antigens and begins immune response: increases the number of T-cells, activates B-cells (specific to antigen), and activates cytotoxic T-cells
Antigen
a toxin or other foreign substance which induces an immune response in the body
Cytotoxic T-Lymphocytes
Kill antigens by producing antibodies
B-Lymphocytes
Once activated (by T-cells) undergo mitosis, differentiating into plasma cells which release anti-bodies and memory cells
HIV
Attacks helper-T-cells inhibiting the activation of cytotoxic T-cells and activation of B-cells
Penicillin
Kills bacteria by inhibiting production of peptidoglycan (maintains rigid of cell wall), causing bacteria cells to leak.
Function of vaccinations
Creates memory B cells specific to targeted antigen