Blood Vessels Flashcards

1
Q

types of blood vessels (and diameters)

A
elastic arteries (1 - 2.5cm)
muscular arteries (0.3 mm - 1 cm)
arterioles (10 um - 0.3 mm)
capillaries (8 - 10 um)
venules (8 - 100 um)
veins
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2
Q

layers of arteries

A

lumen - blood filled inner space
tunica intima
tunica media
tunica externa

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3
Q

tunica intima

A

endothelium made up of simple squamous epithelium
subendothelial layer
internal elastic membrane

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4
Q

tunica media

A

sheets of smooth muscle and elastic fibers
external elastic membrane
contraction causes vasoconstriction, relaxation causes vasodilation

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5
Q

tunica externa

A

composed of collagen fibers

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6
Q

elastic arteries

A

for conducting blood
largest arteries
diameter 1-2.5 cm
high elastin content: dampens surge of blood pressure
walls of vessels supplied by vasa vasorum
proximal to muscular arteries

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7
Q

muscular arteries

A

for distributing blood
lie distal to elastic arteries
diameter 0.3 mm - 1 cm
tunica media is thick, smooth muscle and elastin fibers
unique feature: internal and external elastic membranes that dampen the pulsatile pressure produced by the heartbeat

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8
Q

arterioles

A

smallest arteries
diameters 10 um - 0.3 mm
larger arterioles possess the same tunics
diameter of arterioles controlled by: local factors in the tissues, autonomic nervous system

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9
Q

capillaries

A

smallest blood vessels
diameter 8 - 10 um
red blood cells pass through single file
site specific functions

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10
Q

site-specific functions of capillaries

A

lungs: oxygen enters blood, carbon dioxide leaves blood
other tissues: oxygen leaves blood, carbon dioxide enters blood
small intestines: receive digested nutrients
endocrine glands: pick up hormones
kidneys: remove nitrogenous and other wastes

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11
Q

poorly vascularized tissues

A

tendons and ligaments are poorly vascularized

epithelia and cartilage are avascular

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12
Q

precapillary sphincters

A

regulate the flow of blood to tissues
when relaxed, sphincters are open and blood flows to true capillaries
when constricted, sphincters are closed and blood flows to metarteriole thoroughfare channel and bypasses the capillaries

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13
Q

types of capillaries

A

continuous capillaries - the least permeable type of capillaries
fenestrated capillary - large fenestrations (pores) increase permeability in small intestines and kidneys
sinusoidal capillary - most permeable with wide intercellular clefts in bone marrow, liver, and spleen

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14
Q

continuous capillaries

A

most common type
relatively low permeability
found in skin, muscle, blood-brain barrier
capillaries have complete tight junctions of endothelial cells which prevent movement
vital molecules pass through via highly selective transport mechanisms (endothelial cell membranes and pinocytotic vesicles)
not a barrier against: oxygen, carbon dioxide, some drugs

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15
Q

where are continuous capillaries found?

A

skin, muscle, blood-brain barrier

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16
Q

pericytes around continuous capillaries

A

contractile cells that wrap around endothelial cells, embedded in basement membrane
communicate with and help sustain endothelial cells

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17
Q

fenestrated capillaries

A
large fenestrations (pores) result in increased permeability
found in kidneys and small intestines
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18
Q

sinusoidal capillaries

A
most permeable capillaries
wide open intercellular clefts (gaps of unjoined membrane through which small molecules can enter and exit)
usually also fenestrated
incomplete basement membrane
have a large diameter and twisted course
found in bone marrow, liver, and spleen
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19
Q

where are fenestrated capillaries found?

A

small intestine, kidneys

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20
Q

where are sinusoidal capillaries found?

A

liver, bone marrow, spleen

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21
Q

routes of permeability in capillaries

A
  1. endothelial cell membranes
  2. pinocytotic vesicles
  3. fenestrations (fenestrated capillaries)
  4. intercellular clefts (sinusoidal capillaries)
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22
Q

smallest venules are called

A

postcapillary venules

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23
Q

thickest tunic in veins

A

tunica externa

rich in collagen fibers

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24
Q

mechanisms to move venous blood

A

valves - in some valves, prevent backflow of blood, particularly in limbs
skeletal muscles - press against vein walls and help pump blood toward the heart

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25
vascular anastomoses
vessels interconnect to form vascular anastomoses that enable organs to receive blood from more than one blood vessel veins anastomose more than arteries
26
vasa vasorum
vessel of vessels tiny arteries, capillaries, and veins nourish outer region (tunica externa) of large vessel walls the inner half of large vessels receive nutrients from luminal blood
27
pulmonary circulation
pulmonary trunk extends from right ventricle, divides into right and left pulmonary arteries, and carries deoxygenated blood to the lungs superior and inferior pulmonary veins carry oxygenated blood into the left atrium
28
systemic arteries
carry oxygenated blood away from the heart | the aorta, for example
29
aorta
largest artery in the body ascending aorta arises from the left ventricle and early branches form coronary arteries aortic arch lies posterior to manubrium descending aorta continues from the aortic arch divides into right and left common iliac arteries
30
aortic arch
lies posterior to the manubrium brachiocephalic trunk: right subclavian and common carotid arteries left common carotid artery left subclavian
31
descending aorta
continues from the aortic arch thoracic aorta in the region of T15-T12 abdominal aorta ends at L4
32
common carotid arteries
located in anterior triangle of neck | 2 branches: external and internal
33
external common carotid artery branches
``` maxillary artery facial artery lingual artery superficial temporal artery occipital artery superior thyroid artery ```
34
internal common carotid artery branches
ophthalmic artery middle cerebral artery anterior cerebral artery posterior communicating artery
35
cerebral artery circle (circle of Willis)
forms a loop around pituitary gland and optic chiasm anterior blood supply from internal carotids posterior blood supply from vertebral arteries
36
vertebral arteries
supply blood to posterior part of brain extend off subclavian artery and ascend through foramina in transverse processes of cervical vertebrae C1-C6 merge to form basilar artery, splits into posterior cerebral arteries
37
arteries of the arm
subclavian --> axillary --> brachial --> radial/ulnar --> superficial/deep palmar arch, digital arteries
38
axillary artery becomes the brachial artery at the
inferior border of teres major muscle
39
arteries of the thorax
anterior and posterior intercostal arteries | lateral and internal thoracic arteries
40
arteries of the abdominal aorta
``` inferior phrenic celiac trunk superior mesenteric suprarenal renal gonadal inferior mesenteric common iliac ```
41
celiac trunk
main branches supply the viscera in superior abdomen | 3 main branches: left gastric, splenic, common hepatic
42
superior mesenteric artery
arteries extend to jejunum, ileum, proximal half of colon (cecum, appendix, ascending colon, first half of transverse colon)
43
inferior mesenteric artery
arteries extend to distal half of colon (second half of transverse colon, descending colon, sigmoid colon, rectum)
44
artery branches off the internal iliac
``` gluteal obturar internal pudendal middle rectum visceral uterine ```
45
arteries of the pelvis and lower limbs
``` internal iliac external iliac femoral popliteal anterior tibial posterior tibial fibular dorsalis pedalis plantar plantar arch ```
46
3 major veins enter the right atrium
``` superior vena cava (returns blood from structures superior to diaphragm) inferior vena cava (returns blood from structures inferior to diaphragm) coronary sinus (returns blood from cardiac muscle) ```
47
coronary sinus
supplies right atrium receives blood via coronary sinus in posterior coronary sulcus drains from great, middle, and small cardiac veins
48
dural sinuses in brain
venous channels found between periosteal dura and the brain walls of the dural venous sinuses are lined with endothelium internal jugular vein drains the venous sinuses
49
dural sinuses in the head and neck
``` super and inferior sagittal sinuses straight sinus cavernous sinus transverse sinus sigmoid sinus ```
50
deep veins of the upper limbs
``` subclavian axillary brachial basilic cephalic radial ulnar deep palmar arch digital ```
51
superficial veins of the upper limbs
basilic cephalic median cubital (site of blood draw) median antebrachial
52
veins of the thorax
azygos hemiazygos accessory hemiazygos intercostals
53
veins of the abdomen
``` inferior phrenic hepatic suprarenal renal lumbar gonadal ```
54
hepatic portal system
specialized part of the vascular circuit picks up digested nutrients from the stomach and intestine and delivers nutrients to the liver for processing and storage
55
veins that supply the hepatic portal system
``` gastric gastroepiploic splenic inferior mesenteric superior mesenteric ```
56
first capillary bed of hepatic portal system
in the stomach and intestines | receives digested nutrients and then drains into hepatic portal veins
57
second capillary bed of hepatic portal system
liver sinusoids nutrients reach liver cells for processing (still oxygen-poor) blood then reenters systemic circulation
58
superficial veins of the pelvis and lower limbs
small saphenous great saphenous arise from the dorsal venous arch
59
deep veins of the pelvis and lower limbs
``` iliac femoral popliteal anterior tibial posterior tibial fibular dorsalis pedalis plantar plantar arch digital ```
60
aneurysm
dilation of blood vessel wall that may burst
61
example of venous disease
varicose veins
62
atherosclerosis
fat deposits in arteries