Blood Glucose Homeostasis Flashcards

1
Q

What is hypoglycemia and hyperglycemia?

A

Low and high sugar

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2
Q

True or false: blood sugar/ glucose regulates many pathways in our body

A

True

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3
Q

Why do we want glucose to be in a normal range in our body?

A

It keeps our body in homeostasis. Glucose provides energy to our cells.

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4
Q

Why do they look for sugar concentration at doctors office?

A

To see if you’re at risk for diabetes.

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5
Q

What is the normal glucose concentration in blood? (In mmol )

A

5 mmol

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6
Q

Why is glucose in the blood so important to think about?

A
  • muscles use glucose during exercise
  • when glucose gets to cells, it produces ATP
  • our brains cannot function without glucose.
  • glucose is critical for muscle and the muscle uses a ton of it.
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7
Q

How do we get glucose in our bloodstream?

A

We consume carbohydrates, and if we don’t, our liver can make glucose from protein

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8
Q

What muscle is constantly burning glucose?

A

The brain. it doesn’t burn fat or protein.

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9
Q

What will happen to your brain with no glucose?

A

Groggy and tired first. Then we get weak, loss of consciousness and then death.

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10
Q

What is the brains emergency fuel?

A

Ketones. But prefers glucose. Won’t consume anything else.

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11
Q

Every muscle except the brain requires what hormone to get to the muscle cells?

A

Insulin.

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12
Q

What does a PET scan do?

A

Uses isotopes to measure glucose uptake into the cell.

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13
Q

Where does the most glucose uptake occur in the body during exercise?

A

The part you are using most (ex. Sprinters will be legs).

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14
Q

What is the amount of glucose in the blood stream before a meal vs. After a meal?

A

Before: 4 grams. After: 7.3 grams.

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15
Q

How many litres of blood does the average adult have?

A

4.5L of blood

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16
Q

What is the glucose homeostatic range in mmol?

A

4-9 mmol/L

17
Q

Why is high blood sugar not good?

A

Many bad things like amputation and blindness can happen. Too much high blood sugar overtime predicts all sorts of bad outcomes. Predicts CVD and cancer.

18
Q

Why is low blood sugar not good?

A

You can’t feed brain and you can pass out if it’s low enough, even die.

19
Q

True or false: over time, hyperglycema is damaging to cells.

A

True.

20
Q

True or false: hypoglycemia is not dangerous immediately.

A

False, dangerous immediately.

21
Q

Where is the glucose sensor needle measuring from?

A

The interstitial fluid.

22
Q

What causes an elite level athlete who doesn’t have diabetes to have high sugar when they’re in competition?

A

Adrenaline, stress, other hormones. Fueling.

23
Q

What does eating vs. exercising do to glucose levels?

A

Eating highers it, exercising lowers it.

24
Q

What are the main hormones that affect our blood sugar levels?

A

Lower: insulin, higher: glucagon.

25
Q

What hormone takes glucose out of the bloodstream, out of the fluid, and pushes it into the cells, muscle cells, fat cells, liver cells

A

Insulin

26
Q

Where does glucagon come from?

A

The pancreas.

27
Q

What organ is so important in maintaining glucose homeostasis?

A

The liver.it holds glucose in the form of glycogen

28
Q

What happens when insulin goes up?

A

Glucose is pushed into the liver and muscles

29
Q

What happens when insulin goes down?

A

Squeezes glucose out the liver to keep blood sugar up.

30
Q

True or false: insulin brings sugar up and glucagon brings sugar down.

A

False. Vice versa.

31
Q

True or false: insulin brings sugar up and glucagon brings sugar down.

A

False. Vice versa.