Blood Ch15 Flashcards
Hematology
Study of Blood
Functions of blood
Transport-O, CO2, nutrients, waste
Regulation-fluid+electrolyte balance, thermoreg.
Protection-Pathogens, blood loss
Blood composed of ______ and ______
Plasma and cells
Pale, yellowish fluid, has water and proteins (albumin), gasses, ions, waste
Plasma
_____ is plasma w/o proteins; after clotting
Serum
Cells consist of ____ ______ _____
Erythrocytes (RBC), Leukocytes (WBC), Thrombocytes (platelets)
Percentage of blood cells in a sample of blood
Hematocrit 45% blood 55% plasma
Layer of WBC and platelets that sits on RBCs in a hematocrit
Buffycoat
The formation of blood cells
Hematopoiesis
Differentiates between RBC WBC and platelets under different growth factors
Stem Cells
Stem cells can’t differentiate, can’t produce enough blood cells, bone marrow is suppressed
Marrow Suppression / Myelo suppression
Deficiency of RBC
Anemia
Deficiency of WBC
Leukopenia
Thrombocytopenia
Deficiency of thrombocytes
Polycythemia
overproduction of RBC
Leukocytosis
Overproduction of WBC
Thrombocytosis
Overproduction of thrombocytes
4.5-6.0 million in one microliter
RBC
Immature RBC; response of blood loss; net-like appearance
Reticulocyte
Loses its nucleus as it matures; bend and twist to fit through the capillaries
RBC
HEMoglobin
Iron and oxygen
HemoGLOBIN
CO2
Oxygenated hemoglobin
Oxyhemoglobin (bright red)
Unoxygenated hemoglobin
Hemoglobin (blue-red)
Body requires ____ _____ _____ for hemoglobin synthesis
Iron, Folic Acid, B12
Stimulates bone marrow to produce additional RBCs
Erythropoietin (EPO)
RBC live ____ days
120
Phagocytize materials (clean up;uses pseudopods); Protect from infection
WBC
Dead tissue damaged by bacteria; dead WBC
Pus
WBC containing granules
Granulocytes
Granuclocytes:___ ____ _____
WBC containing granules
Neutrophil
Eosinophil
Basophils
Neutrophil
don’t stain 55-75% of WBC; seg=mature, bands=mature; phagocytosis
Eosinophil
stain red; inflammatory response;^ in parasitic infections
Basophils
blue; inflammatory resp.;produce heparin(reduce clotting)
Agranulocytes
WBC w/ no granules
Lymphocytes
Monocytes
Lymphocytes
1/3 of WBCs; immune response
Monocytes
phagocytotic macophage, fixed and wandering`
Platelets
control blood loss
Differential White Count
Number of each whites and percentage
Complete Blood Count
Bloodtest gives info on # of RBC, WBC, platelets, hemoglobin, hematocrit, maturity of cells
Hemostasis & 4 steps
stops bleeding
vessel spasm-vessel constricts
platelet plug- stick to eachother/damaged tissue
clot-chemical reaction=fibrin(net of rbcs&platelets)
Clot contraction
Edges of clot pull together; water is squeezed out
Pulmonary Embolism
Clot breaks off and gets stuck in lungs
Coumadin
Prevents clot formation
Thrombus
blood clot
Embolus
Traveling Blood clot
Blood types based on ___
Antigens in blood
Aglutination & Hemolysis & caused by
Clumping of RBCs & RBCs burst caused by bad match in blood
Erythroblastosis fetalis
When a 2nd time pregnant woman develops RH antibodies in the first pregnancy and problem lies in 2nd pregnancy