25 electrolyte balance acid/base Flashcards
Intracellular
inside cells, 2/3 of water found here; K+, PO4-, Mg+
Extracellular
outside of cells 1/3 of water; ^Na+, Cl-, HCO3-; interstitial fluid, blood vessesl (plasma), lymphatic vessels (lymph); cavities: cerebral spinal fluid, glandular secretions
Water electrolytes move through:
filtration, osmosis, diffusion, active transport pump- move against concentration gradient [atp]
Water balance- input has to equal
output; 2500 ml/day
Fluid intake from
60% fluid/drink, 30% food, 10% water from metabolism (breakdown of glucose=water&glucose, )
Primary indicator of need for water intake
Thirst
Fluid excreted by
kidneys/urine (primary regulator adh [in] aldosterone [out], skin/lungs 28%, feces/sweat 12%
Dehydration
v blood volume/pressure=hypovolemic shock
Electrolytes
produce cations+ and anions- when dissolved
Sodium
chief extracellular cation 90% of cations in extracellular fluid
Hyper/hypo natremic
too much/little sodium in the blood-controlled by aldosterone secreted by adrenal cortex
Hypernatremic
lose water, not sodium high concentration of Na; diuretics- lose water through urine; diabetes- lose glucose in urine that takes water with it
Hyponatremic
^water intake vNa concentration
Potassium
chief intracellular cation; regulated by aldosterone- stimulates distal tubule of kidney to excrete potassium into urine
Hyperkalemic
malfunctioning kidneys unable to excrete K; excess Potassium in the blood
Hypokalemic
Prolonged use of Diuretics=loss of potassium; caused by vomiting/diarrhea
Calcium
regulated by vCalcitonin and parathyroid hormone^
Chloride
chief extracellular anion
Bicarbonate HCO3-
alkaline anion that removes excess acidity from the body; excreted by kidneys as the body needs it
Normal pH of blood
acidosis 7.35-7.45 alkalosis
___ governs ph
H+; ^-lower number acidic; v higher number alkaline
Metabolization of carbs, proteins, lipids effect on H+
Increase
Mechanisms to regulate acid/base balance
1) Buffers
2) Respirations
3) Kidneys
Mechanisms to regulate acid/base balance:
Buffers
quick, limited capacity; accept H+ when acidic/low ph; donate H+ when alkaline/high ph
Mechanisms to regulate acid/base balance:
Respirations
moderate, moderate capacity; ^CO2=^H+=acidic; v CO2=v H+ = alkaline
Mechanisms to regulate acid/base balance:
Kidneys
slow; high capacity; retain or excrete H+/HCO3- in forming urine
Acidosis
ph below 7.35
Respiratory caused Acidosis
hypoventilation; emphysema, chest injury where it hurts to breathe; buffers accept H+; renal compensation of respiratory acidosis- excrete H+
Metabolic caused Acidosis
diarrhea=loss of alkaline bicarbonate/vomitting/->respiratory compensation of metabolic acidosis
Alkalosis
ph greater than 7.45
Respiratory caused alkalosis=
renal compensation of respiratory alkalosis-donate H+
Metabolic caused alkalosis
vomiting of acid stomach contents -respiratory compensation of metabolic alkalosis-breathing slows = H+^
Buffers
immediate response then respiratory, kidney step in after