Blood cancer histology Flashcards

1
Q

What does this histology depict?

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia

A

What does this histology depict?

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia

prominent myeloid hyperplasia without significant increase in blasts

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2
Q

Which of the following is the most common leukemia in the pediatric population

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia

A

Which of the following is the most common leukemia in the pediatric population

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia: accounting for up to 80% of cases in this group vs. 20% of cases in adults.

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3
Q

Which of the following is the most aggressive cancer with a variable prognosis

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia

A

Which of the following is the most aggressive cancer with a variable prognosis

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia

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4
Q

Which of the following typically arises from reciprocal translocation and fusion of BCR on chromosome 22 and ABL1 on chromosome 9

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia

A

Which of the following typically arises from reciprocal translocation and fusion of BCR on chromosome 22 and ABL1 on chromosome 9

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia

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5
Q

This slide depicts which of the following

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia

A

This slide depicts which of the following

Chronic myeloid leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia
Acute lymphocytic leukemia

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6
Q

A 65-year-old male with hypertension presented to his primary care provider for a regular check-up. A complete blood picture revealed a white blood cell count of 100,000/mm^3. The patient is asymptomatic. A peripheral smear shows significant lymphocytosis. What is the most likely diagnosis?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

A 65-year-old male with hypertension presented to his primary care provider for a regular check-up. A complete blood picture revealed a white blood cell count of 100,000/mm^3. The patient is asymptomatic. A peripheral smear shows significant lymphocytosis. What is the most likely diagnosis?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

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7
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

C. Acute lymphocytic leukemia

In acute lymphoblastic leukemia (ALL), too many immature lymphocytes are present in the bone marrow and the blood. Normally, these cells are relatively rare, but in ALL, they continuously multiply and are overproduced by the bone marrow, causing fatigue, anemia, fever, and bone pain due to the spread of these cells into the bone and joint surfaces. This slide shows many more immature lymphocytes than you would typically expect to see in a blood smear.

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8
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

B. Chronic myelogenous leukemia

Chronic Myelogenous Leukemia (CML) is a form of leukemia caused by a chromosomal translocation known as the Philadelphia chromosome, which you will study in detail in Genetics. It is characterized by the unregulated growth of myeloid cells in the bone marrow, resulting in the presence of large numbers of mature and immature granulocytes in both the bone marrow and the blood.

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9
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

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9
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

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10
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

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11
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

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12
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

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13
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

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14
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

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15
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

16
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

Lymphocytes are small, mature without nucleoli, several smudged cells are present (high power).

17
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

18
Q

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia

A

What does this slide depict?

A. Acute myelogenous leukemia
B. Chronic myelogenous leukemia
C. Acute lymphocytic leukemia
D. Chronic lymphocytic leukemia