blood 1 Flashcards
how much of blood is plasma
3 L
what is blood
a connective tissue composed of cellular elements suspended in a fluid matrix
whats the primary difference between plasma and the interstitial fluid
plasma proteins
whats the most abundant type of plasma proteins
albumins
what are albumins good for
they are good carriers for various substances
how much blood does cellular elements take up
2L
whats the most abundant cellular element
erythrocyte
what c causes filtration
hydrostatic pressure
whats our normal blood volume
5L
which sex has more blood ? how much?
males have more with about 80ml/kg
females have about 70ml/kg
what causes the difference in volume of blood between sexes?
its usually a difference in red blood cell numbers
what are the three components of blood
hematocrit
buffy coat
plasma
what is one way clinicians look if you have a disease
look at the hematocrit layer
what is the hematocrit
volume occupied by RBCs
what is the buffy coat layer
WBC and platelets
what is the plasma layer
plasma proteins
electrolytes
lipids
which layer takes up the most space
plasma with 60%
what is hematopoiesis
production of blood cells
where does it happen in adults
pelvis, spine, ribs, cranium, and proximal end of long bones
where does hematopoiesis happen?
in bone marrow
what are the cells produced the most (75%)? why?
WBCs - they have a very short lifespan
what can hematopoiesis stem cells do
specialized stem cells that are capable of regenerating themselves and then transform into basically any cell
how long to RBCs normally last
about 4 months
what is hemopoiesis guided by
cell signalling molecules (cytokines)