block c lecture 3 Flashcards

reproduction

1
Q

2 functions of testes

A

gametogenesis
endocrine

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2
Q

5 functions of sertoli cells

A

-phagocytosis of defective sperm
-nourish sperm
-paracrine function (growth factors, androgen binding protein)
-barrier function (blood/seminiferous epithelium)
-endocrine function (inhibin, oestrogens, MIF (AMF))

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3
Q

what is the temp requirement for spermatogenesis

A

~34 degrees cel (2-3 degrees below body temp)

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4
Q

what is the temperature for spermatogenesis determined by

A

function of scrotum
blood supply

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5
Q

how is the scrotum adapted to lose heat

A

large surface area
abundant sweat glands

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6
Q

name of the vein that takes deoxygenated blood back to the heart

A

pampiniform plexus

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6
Q

name of the vein that takes deoxygenated blood back to the heart

A

pampiniform plexus

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7
Q

where are testes developed

A

intra-abdominally

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8
Q

what occurs if the testes fail to descend

A

cryptochidism
sterility

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9
Q

4 hormones requires for spermatogenesis

A

GnRH
FSH
LH
testosterone

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10
Q

3 actions of androgens

A

spermatogenesis
external genitalia
ducts and glands

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11
Q

4 actions of androgens

A

spermatogenesis
external genitalia
ducts and glands
2 sexual characteristics

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12
Q

4 main ducts

A

ejaculatory duct
vans deferens
epididymis
urethra

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13
Q

3 accessory glands

A

seminal vesicle
prostate
bulbourethral gland

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14
Q

examples of 2 sex characteristics

A

male pattern baldness
aggressiveness
enlarged larynx - deeper voice
muscle mass

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15
Q

the female duct in early foetal reproductive system

A

mullerian

16
Q

the male duct in early foetal reproductive system

A

wolffian

17
Q

what does failure of foetal testis- no androgen secretion or no androgen receptors result in

A

external genitalia develop along female lines

18
Q

the 3 phases of menstrual phase

A

menstrual phase
follicular phase
luteal phase

19
Q

what days does the menstrual phase occur

A

1-5

20
Q

what days does the follicular phase occur

A

5-14

21
Q

on what day does ovulation occur

A

14

22
Q

what days does the luteal phase occur

A

14-28

23
Q

ovarian events controlled by hormones

A

follicle development
ovulation
corpus luteum development

24
Q

uterine events controlled by hormones

A

endometrium
cervix
motility

25
Q

when does oogenesis occur

A

during intrauterine development in female foetus

26
Q

at birth how many primary oocytes are present

A

2-4 million

27
Q

what occurs during follicular phase

A

endometrium thickens
glands grow
blood vessels grow

28
Q

what occurs during luteal phase

A

thickening of endometrium declines
glands branch, secrete

29
Q

what occurs when spiral arteries dilate

A

inner endometrium becomes ischaemic and tissue dies

30
Q

what changes in the cervix around the time of ovulation

A

thin watery secretion
allows sperm penetration

31
Q

what phases do uterine peristaltic contractions increase

A

increase as follicular phase progresses
increase during menstrual phase

32
Q

what phase do uterine peristaltic contractions decrease

A

during luteal phase

33
Q

in which phase is oestrogen more prominent

A

follicular phase

34
Q

in which phase is progesterone more prominent

A

progesterone

35
Q

in which phase is there reduced levels of oestrogen and progesterone

A

menstrual phase

36
Q

what occurs as a result of increase in oestrogen during follicular phase

A

endometrial development
cervical mucus
increase in contractions

37
Q

what occurs as a result of increase in progesterone during luteal phase

A

gland development and secretion
cervical mucus
decrease in contractions

38
Q

what occurs as a result of reduced levels of oestrogen and progesterone during menstrual phase

A

constriction of spiral arteries
endometrial shedding