block e lecture 3 Flashcards
most important function of the kidneys
regulation of H2O and inorganic ion balance
the 2 components of nephrons
tubular components (contains what will be urine)
vascular components (blood supply)
where does glomerular filtrate drain into
bowmans space
then proximal convoluted tubule
charge of podocytes
-ve
what does the macula sense
GFR by Na
what does the juxtaglomerular (JG) secrete
includes JG cells that secrete renin
what does JGA regulate
renal blood flow, GFR and indirectly Na balance and systemic BP
what is high hydrostatic pressue at glomerular capill due to
short, wide afferent arteriole
(low R to flow) and the long narrow efferent arteriole (high R)
what is GFR controlled by
diameters of aff and efferent arterioles
what does ang II constrict and stimulate
direct constriction of renal arterioles
stimulation of aldosterone synthesis
what is RAAS primary importance
bp
when is RAAS activated
in response to reduced blood flow
what is principle factor in controlling ang II levels
renin release
what makes macula densa more sensitive
enhanced tubuloglomerular feedback
what does aldosterone stimulate
Na reabsorption and K excretion by the renal tube
