block c lecture 2 Flashcards
endo hormonal control of growth development
name of growth hormone
somatotrophin
5 things growth hormone effects
-growth
-Ca2 and phosphate retention
-increased protein synthesis
-increased blood glucose
-increased circulating FFA
where does cartilage forms
epiphyseal plate
what is cartilage converted to bone by
osteoblasts
what are actively proliferating cartilage tissue
chondrocytes
4 steps to growth of bone
-production of cartilage by chondrocytes of epiphyseal plate
-conversion of cartilage to bone at shaft edge of plate
-epyphyseal plate becomes converted to bone
-growth plates
what promotes the conversions required to grow bone
growth hormone
what is liver a source of
glucose
what does growth hormone in adipose tissue do
accelerated lipolysis
what does increased circulating FFA lead to a reduction in
tissue glucose uptake
what does growth hormone act indirectly on
liver
IGF1
growth
what does ghrelin promote
eating
2 ways in which dwarfism is caused
-growth hormone deficiency before epiphyseal closure
-IGF-1 deficiency
what does growth hormone excess before growth cessation cause
gigantism
what does growth hormone excess aftergrowth cessation cause
acromegaly
