Biochemistry: Workshop Flashcards

1
Q

a chemical reaction with a positive enthalpy change may occur spontaneously when

A

coupled to a bigger reaction with a negative enthalpy change

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2
Q

a chemical reaction with a large and negative free energy change

A

is likely to be irreversible in the cell

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3
Q

hydrolysis of ATP is a strong

A

exergonic reaction

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4
Q

if a reaction has a large negative free energy change its likely to happen to a _ extent with _ amounts of product formed

A

large

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5
Q

at Keq the change in free energy of a reaction is

A

zero

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6
Q

a polar molecule is

A

a molecule with opposite charges at opposite ends

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7
Q

amino acids are classified according to

A

their strictures and properties of side chains

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8
Q

hydrophobic means

A

no net charge - non-polar

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9
Q

peptide bonds are (non/planar)

A

planar

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10
Q

peptide bond formation is a _ reactions

A

hydrolysis

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11
Q

what two groups of two amino acids form a peptide bond

A

an amino group and hydroxyl group

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12
Q

what type of bonding is responsible for the secondary structures of proteins

A

H bonding between C=O and N-H groups of peptide bonds

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13
Q

what is quaternary structure

A

spatial arrangement of 2+ polypeptide subunits into a single functioning complex

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14
Q

what is a protein domain

A

discrete region of polypeptide chain that has folded into a self-contained 3D structure

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15
Q

new nucleotides are added to the _ end of growing nucleic acids

A

3’

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16
Q

introns are

A

non-coding sequences

17
Q

splicing occurs in the

A

nucleus

18
Q

proteins are synthesised from the _ terminus to the _ terminus

A

N to C

19
Q

nonsense mutations do what

A

introduce a stop codon

20
Q

what do buffers do

A

control the pH of a reaction mixture

21
Q

what reactions in a protein are disrupted by the extremes of pH

A

hydrophobic interactions